Zobrazeno 1 - 10
of 4 737
pro vyhledávání: '"Horiike A"'
Autor:
Narufumi Kameya, Itsuki Sakai, Kengo Saito, Toshihide Hamabe-Horiike, Yohei Shinmyo, Mitsutoshi Nakada, Satoru Okuda, Hiroshi Kawasaki
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract The functional significance of the morphological and genetic changes that occurred in the brain during evolution is not fully understood. Here we show the relationships between evolutionary changes of the brain and glymphatic circulation. We
Externí odkaz:
https://doaj.org/article/6f6cecad1451490db85a17a8b3a8a03f
Autor:
Hitoshi Toyoda, Atsuo Kuramasu, Masahiro Hosonuma, Masakazu Murayama, Yoichiro Narikawa, Junya Isobe, Yuta Baba, Kohei Tajima, Eiji Funayama, Midori Shida, Yuki Maruyama, Aya Sasaki, Yuya Hirasawa, Toshiaki Tsurui, Hirotsugu Ariizumi, Tomoyuki Ishiguro, Risako Suzuki, Sei Kobayashi, Atsushi Horiike, Noriko Hida, Takehiko Sambe, Koji Nobe, Satoshi Wada, Hitome Kobayashi, Mayumi Tsuji, Shinichi Kobayashi, Takuya Tsunoda, Yoshifumi Kudo, Yuji Kiuchi, Kiyoshi Yoshimura
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Natural killer group 2 member D ligands (NKG2DLs) are expressed as stress response proteins in cancer cells. NKG2DLs induce immune cell activation or tumor escape responses, depending on their expression. Human pancreatic cancer cells, PANC-
Externí odkaz:
https://doaj.org/article/9cc18d13b98e4eae855bec63d4c5642c
Autor:
Saeko Kashimura, Miki Sato, Takahito Inagaki, Masaoki Kin, Ryo Manabe, Sojiro Kusumoto, Atsushi Horiike, Takuya Tsunoda, Mari Kogo
Publikováno v:
Thoracic Cancer, Vol 15, Iss 28, Pp 2049-2060 (2024)
Abstract Background The relationship between the combination of platelet count and neutrophil‐lymphocyte ratio (COP‐NLR) and prognosis in patients with advanced non‐small cell lung cancer (NSCLC) treated with immune checkpoint inhibitor (ICI) c
Externí odkaz:
https://doaj.org/article/fcaaca174d4f4c25a101f80f1ed991cb
Autor:
Yuya Hirasawa, Yutaro Kubota, Emiko Mura, Risako Suzuki, Toshiaki Tsurui, Nana Iriguchi, Tomoyuki Ishiguro, Ryotaro Ohkuma, Masahiro Shimokawa, Hirotsugu Ariizumi, Atsushi Horiike, Satoshi Wada, Takeshi Yamashita, Tomotake Ariyoshi, Satoru Goto, Koji Otsuka, Masahiko Murakami, Yuji Kiuchi, Kiyoshi Yoshimura, Takuya Tsunoda
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionImmune checkpoint inhibitors (ICIs) have emerged as a promising treatment option for esophageal cancer (EC). Although ICIs enable long-term survival in some patients, the efficacy of ICIs varies widely among patients. Therefore, predictiv
Externí odkaz:
https://doaj.org/article/ec9c13c60c4d45eb834f44c57b5372fe
Publikováno v:
Regenerative Therapy, Vol 26, Iss , Pp 811-818 (2024)
Calcium oscillations are rhythmic fluctuations of the intracellular concentration of calcium ions (Ca2+). As Ca2+ evokes various cellular processes, its intracellular concentration is tightly regulated. Ca2+ oscillations control biological events, in
Externí odkaz:
https://doaj.org/article/6f7e5e396b0f41739290d73800c7aa52
Autor:
Masakazu Murayama, Masahiro Hosonuma, Atsuo Kuramasu, Sei Kobayashi, Akiko Sasaki, Yuta Baba, Yoichiro Narikawa, Hitoshi Toyoda, Junya Isobe, Eiji Funayama, Kohei Tajima, Aya Sasaki, Yuki Maruyama, Yoshitaka Yamazaki, Midori Shida, Kazuyuki Hamada, Yuya Hirasawa, Toshiaki Tsurui, Hirotsugu Ariizumi, Tomoyuki Ishiguro, Risako Suzuki, Ryotaro Ohkuma, Yutaro Kubota, Atsushi Horiike, Takehiko Sambe, Mayumi Tsuji, Satoshi Wada, Shinichi Kobayashi, Toshikazu Shimane, Takuya Tsunoda, Hitome Kobayashi, Yuji Kiuchi, Kiyoshi Yoshimura
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract The low response rate of immune checkpoint inhibitors (ICIs) is a challenge. The efficacy of ICIs is influenced by the tumour microenvironment, which is controlled by the gut microbiota. In particular, intestinal bacteria and their metabolit
Externí odkaz:
https://doaj.org/article/7f87f822bfdf411aabf1cc2f6ca5007b
Publikováno v:
In Surface Science March 2025 753
Autor:
Mayuko Yoshino, Yoshitake Shiraishi, Kengo Saito, Narufumi Kameya, Toshihide Hamabe-Horiike, Yohei Shinmyo, Mitsutoshi Nakada, Noriyuki Ozaki, Hiroshi Kawasaki
Publikováno v:
Neuroscience Research, Vol 200, Iss , Pp 1-7 (2024)
The human cerebrum contains a large amount of cortico-cortical association fibers. Among them, U-fibers are short-range association fibers located in white matter immediately deep to gray matter. Although U-fibers are thought to be crucial for higher
Externí odkaz:
https://doaj.org/article/aa9bc166c4a74d2382f6c0b1f6cf157b
Autor:
Yasufumi Katanasaka, Harumi Yabe, Noriyuki Murata, Minori Sobukawa, Yuga Sugiyama, Hikaru Sato, Hiroki Honda, Yoichi Sunagawa, Masafumi Funamoto, Satoshi Shimizu, Kana Shimizu, Toshihide Hamabe-Horiike, Philip Hawke, Maki Komiyama, Kiyoshi Mori, Koji Hasegawa, Tatsuya Morimoto
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Protein arginine methyltransferase 5 (PRMT5) is a well-known epigenetic regulatory enzyme. However, the role of PRMT5-mediated arginine methylation in gene transcription related to cardiac fibrosis is unknown. Here we show that fibroblast-sp
Externí odkaz:
https://doaj.org/article/c2bc5c10072540838079235756f4f6b3
Publikováno v:
In Regenerative Therapy June 2024 26:811-818