Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Horia N. Roman"'
Autor:
Roozbeh Siavash Moakhar, Sebastian Wachsmann-Hogiu, Sara Mahshid, Ayyappasamy Sudalaiyadum Perumal, Juanjuan Liu, Horia N. Roman
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
We developed an inexpensive, portable platform for urea detection via electrochemistry by depositing silver nanoparticles (AgNPs) on a commercial glucose test strip. We modified this strip by first removing the enzymes from the surface, followed by e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fafa92515708e1249d7707845c949bed
https://doaj.org/article/910cf3e8f24e4231904570fcf8ae4def
https://doaj.org/article/910cf3e8f24e4231904570fcf8ae4def
Autor:
Lennart Hilbert, Genevieve Bates, Horia N Roman, Jenna L Blumenthal, Nedjma B Zitouni, Apolinary Sobieszek, Michael C Mackey, Anne-Marie Lauzon
Publikováno v:
PLoS Computational Biology, Vol 9, Iss 10, p e1003273 (2013)
The proteins involved in smooth muscle's molecular contractile mechanism - the anti-parallel motion of actin and myosin filaments driven by myosin heads interacting with actin - are found as different isoforms. While their expression levels are alter
Externí odkaz:
https://doaj.org/article/494dcae7d24f47eea35101091263a3f4
Autor:
Saba Al Heialy, Paul-André Risse, Anne-Marie Lauzon, Toby K. McGovern, James G. Martin, Mauro Novali, Soroor Farahnak, Melissa A. Zeroual, Horia N. Roman
Publikováno v:
The Journal of Immunology. 194:5626-5634
Contact between airway smooth muscle (ASM) cells and activated CD4+ T cells, a key interaction in diseases such as asthma, triggers ASM cell proliferation and enhances T cell survival. We hypothesized that direct contact between ASM and CD4+ T cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9406a53c695bb07f2942afc838a4b6d
https://doi.org/10.4049/jimmunol.1401718
https://doi.org/10.4049/jimmunol.1401718
Publikováno v:
Analytical Chemistry. 87:2582-2587
In vitro motility and laser trap assays are commonly used for molecular mechanics measurements. However, chemicals cannot be added during these measurements, because they create flows that alter the molecular mechanics. Thus, we designed a microfluid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49d1ed2cc9f10a547b6a6847491d10b8
https://doi.org/10.1021/ac503963r
https://doi.org/10.1021/ac503963r
Autor:
Oleg S. Matusovsky, Horia N. Roman, Nedjma B. Zitouni, Anne-Marie Lauzon, Andrea Benedetti, Apolinary Sobieszek, Lennart Hilbert, Linda Kachmar, Gijs Ijpma
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1830:4634-4641
Smooth muscle has the distinctive ability to maintain force for long periods of time and at low energy costs. While it is generally agreed that this property, called the latch-state, is due to the dephosphorylation of myosin while attached to actin,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3313b7d99097de806da6048bd63aad9e
https://doi.org/10.1016/j.bbagen.2013.05.042
https://doi.org/10.1016/j.bbagen.2013.05.042
Autor:
Berndt Nilius, Luke J. Janssen, Peter Dyrda, Horia N. Roman, Lindsay DoHarris, Dusan Lukic, Tariq Aziz, Tracy Tazzeo, Anne-Marie Lauzon
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 44:213-221
Despite the emerging use of bronchial thermoplasty in asthma therapy, the response of airway smooth muscle (ASM) to extreme temperatures is unknown. We investigated the immediate effects of exposing ASM to supraphysiologic temperatures. Isometric con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a49936a140d845818d3822505a506c9e
https://doi.org/10.1165/rcmb.2009-0259oc
https://doi.org/10.1165/rcmb.2009-0259oc
Autor:
Horia N. Roman, Nedjma B. Zitouni, Apolinary Sobieszek, Andrea Benedetti, Anne-Marie Lauzon, Linda Kachmar
Smooth muscle has the unique property of maintaining tension with low ATP consumption. It is generally accepted that this property, called the latch-state, results from the dephosphorylation of myosin while attached to actin. However, detached dephos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04d508aa9a0da2eb25855d76db49f675
https://europepmc.org/articles/PMC4165515/
https://europepmc.org/articles/PMC4165515/
Autor:
Anne-Marie Lauzon, Jenna L. Blumenthal, Nedjma B. Zitouni, Apolinary Sobieszek, Genevieve Bates, Lennart Hilbert, Horia N. Roman, Michael C. Mackey
Publikováno v:
PLoS Computational Biology, Vol 9, Iss 10, p e1003273 (2013)
PLoS Computational Biology
PLoS Computational Biology
The proteins involved in smooth muscle's molecular contractile mechanism – the anti-parallel motion of actin and myosin filaments driven by myosin heads interacting with actin – are found as different isoforms. While their expression levels are a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c194ccfd452fc7dfb68793f88f80a493
http://europepmc.org/articles/PMC3812040?pdf=render
http://europepmc.org/articles/PMC3812040?pdf=render
Autor:
Paul-André Risse, Stephane A. Laporte, Kimitake Tsuchiya, Saba Al Heialy, Sana Siddiqui, Melissa A. Zeroual, Horia N. Roman, James G. Martin
Publikováno v:
American journal of respiratory cell and molecular biology. 49(4)
Allergic asthma is a heterogeneous disease with no curative therapies. T cells infiltrate the airway smooth muscle (ASM) layer and may be implicated in airway remodeling and the increase of ASM mass, a cardinal feature of asthma. The mechanism by whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a9762edd5a9e20520266b4d82fd9f64
https://pubmed.ncbi.nlm.nih.gov/23656597
https://pubmed.ncbi.nlm.nih.gov/23656597
Autor:
Nedjma B. Zitouni, Horia N. Roman, Genevieve Bates, Jenna L. Blumenthal, Anne-Marie Lauzon, Michael C. Mackey, Lennart Hilbert
Publikováno v:
Biophysical Journal. 104(2)
Molecular mechanical differences between actin isoforms remain elusive potentially because their sequence differences are limited to the actin regulatory protein binding sites[1]. We executed in vitro motility measurements of smooth muscle myosin wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c32d2ce27c2f966c16e4e52fc635a979