Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Horan Lucas"'
Autor:
Horan, Lucas H., Noller, Harry F.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2007 Mar . 104(12), 4881-4885.
Externí odkaz:
https://www.jstor.org/stable/25427113
Autor:
Stephan A. Grupp, Cheng Liu, Bryan Zimdahl, Horan Lucas, Pengbo Zhang, Hong Liu, David M. Barrett, Yiyang Xu, Jingwei Lu, Liu Lianxing, Vivien W. Chan, Shon Green, Javier Morales, Zhiyuan Yang
Publikováno v:
Cell Discovery
Cell Discovery, Vol 4, Iss 1, Pp 1-13 (2018)
Cell Discovery, Vol 4, Iss 1, Pp 1-13 (2018)
The clinical use of genetically modified T-cell therapies has led to unprecedented response rates in leukemia and lymphoma patients treated with anti-CD19 chimeric antigen receptor (CAR)-T. Despite this clinical success, FDA-approved T-cell therapies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3de2015dc40ad01037abb39b3302cbc1
https://pubmed.ncbi.nlm.nih.gov/30479831
https://pubmed.ncbi.nlm.nih.gov/30479831
Autor:
Lily Zhang, Troy N. Trevino, Suzanne Fischer, Aaron M. Ring, Camillia S. Azimi, Weiwen Deng, David H. Raulet, Michele Ardolino, Horan Lucas, Alexandre Iannello, K. Christopher Garcia
Publikováno v:
Ardolino, M; Azimi, CS; Iannello, A; Trevino, TN; Horan, L; Zhang, L; et al.(2014). Cytokine therapy reverses NK cell anergy in MHC-deficient tumors. Journal of Clinical Investigation, 124(11), 4781-4794. doi: 10.1172/JCI74337. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/3vf1m33v
BASE-Bielefeld Academic Search Engine
BASE-Bielefeld Academic Search Engine
Various cytokines have been evaluated as potential anticancer drugs; however, most cytokine trials have shown relatively low efficacy. Here, we found that treatments with IL-12 and IL-18 or with a mutant form of IL-2 (the “superkine” called H9) p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b44a8c3324f779af320bcec513a90982
https://doi.org/10.1172/jci74337
https://doi.org/10.1172/jci74337
Publikováno v:
Nature. 8/14/2008, Vol. 454 Issue 7206, p899-902. 4p. 2 Black and White Photographs, 1 Diagram, 1 Graph.
Akademický článek
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Autor:
Sun Yan, Hong Liu, Horan Lucas, Juan E. Diaz, Jingwei Lu, Saul J. Priceman, Lu Jin, Cheng Liu, Javier Morales, Binnaz K. Staley, Zhiyuan Yang, Jingyi Xiang, Liu Lianxing, Christine E. Brown, Bin Liu, Yiyang Xu, Li Long, Neal Cheng, Yoko Nakano, Pei Wang, Stephen J. Forman, Vivien W. Chan, Shon Green, Pengbo Zhang, Bryan Zimdahl
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 23(2)
Purpose: The majority of tumor-specific antigens are intracellular and/or secreted and therefore inaccessible by conventional chimeric antigen receptor (CAR) T-cell therapy. Given that all intracellular/secreted proteins are processed into peptides a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c444ad4eb6d9a748f1de84ce55cb8576
https://pubmed.ncbi.nlm.nih.gov/27535982
https://pubmed.ncbi.nlm.nih.gov/27535982
Publikováno v:
Cancer Research. 78:1537-1537
We designed the ARTEMISTM T-cell signaling platform to be a safer ACT therapy by relying on endogenous T-cell signaling factors. We show evidence that the ARTEMISTM receptor disentangles efficacy from CRS and holds the potential to be a clinically sa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b988a9f245a58bd5799feda4ac6d49a
https://doi.org/10.1158/1538-7445.am2018-1537
https://doi.org/10.1158/1538-7445.am2018-1537
Publikováno v:
Nature, vol 454, iss 7206
Martick, M; Horan, LH; Noller, HF; & Scott, WG. (2008). A discontinuous hammerhead ribozyme embedded in a mammalian messenger RNA. Nature, 454(7206), 899-902. doi: 10.1038/nature07117. UC Santa Cruz: Retrieved from: http://www.escholarship.org/uc/item/0s61d1kb
Martick, M; Horan, LH; Noller, HF; & Scott, WG. (2008). A discontinuous hammerhead ribozyme embedded in a mammalian messenger RNA. Nature, 454(7206), 899-902. doi: 10.1038/nature07117. UC Santa Cruz: Retrieved from: http://www.escholarship.org/uc/item/0s61d1kb
Structured RNAs embedded in the untranslated regions (UTRs) of messenger RNAs can regulate gene expression. In bacteria, control of a metabolite gene is mediated by the self-cleaving activity of a ribozyme embedded in its 5′ UTR. This discovery has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d15940cf368ac0ddf539f6c4a106efd6
https://doi.org/10.1038/nature07117
https://doi.org/10.1038/nature07117
Publikováno v:
Genes & development, vol 29, iss 21
Splicing of the Drosophila P-element third intron (IVS3) is repressed in somatic tissues due to the function of an exonic splicing silencer (ESS) complex present on the 5′ exon RNA. To comprehensively characterize the mechanisms of this alternative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b94eec2bac707a76528a64fd653070c
https://escholarship.org/uc/item/2vr3q032
https://escholarship.org/uc/item/2vr3q032
Akademický článek
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