Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Horacio Lazaro"'
Autor:
Chloe D. Wong, Kimiya Ganjooi, Maetja Verbarendse, Jessica M. Travis, Mark H. S. Troftgruben, Hannah R. Mora, Isabella Oldenburg, Robert Lammert, Horacio Lazaro, Scott Eagon
Publikováno v:
Synthetic Communications. 53:32-39
A silver carbonate-based method to synthesize benzoxazoles from imines has been developed. The reaction is extremely mild, tolerates several heterocycles and functional groups, and provides highly functionalized benzoxazoles in modest to good yields.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89af733cb3a39f41d22a98320ace50d7
https://doi.org/10.1080/00397911.2022.2148223
https://doi.org/10.1080/00397911.2022.2148223
Autor:
Marc O. Anderson, Martina Sigal, Ashley Cheung, Jared T. Hammill, Anna S Kashtanova, Korina Eribez, Lauren Loop, Horacio Lazaro, Irene García-Barbazán, Cory A. Chaplan, Kenya Yniguez, Benigno Crespo, Alisje Churchyard, Mofolusho O. Falade, Grant Koch, Briana Belanger, Celine DiBernardo, Jake Baum, Julia E Tryhorn, Amy L. Rice, Katie Kim, Joshua J. Kimball, R. Kiplin Guy, Steven Wilkinson, Benoît Laleu, Nimisha Mittal, Rei Takahashi, Elizabeth A. Winzeler, Francisco-Javier Gamo, Scott Eagon, Kevin J Ahn
Publikováno v:
Journal of Medicinal Chemistry. 63:11902-11919
Malaria remains one of the most deadly infectious diseases, causing hundreds of thousands of deaths each year, primarily in young children and pregnant mothers. Here, we report the discovery and derivatization of a series of pyrazolo[3,4-b]pyridines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b79d343cc463a5cc1561c5e53694b2dc
https://doi.org/10.1021/acs.jmedchem.0c01152
https://doi.org/10.1021/acs.jmedchem.0c01152
Autor:
Scott, Eagon, Jared T, Hammill, Martina, Sigal, Kevin J, Ahn, Julia E, Tryhorn, Grant, Koch, Briana, Belanger, Cory A, Chaplan, Lauren, Loop, Anna S, Kashtanova, Kenya, Yniguez, Horacio, Lazaro, Steven P, Wilkinson, Amy L, Rice, Mofolusho O, Falade, Rei, Takahashi, Katie, Kim, Ashley, Cheung, Celine, DiBernardo, Joshua J, Kimball, Elizabeth A, Winzeler, Korina, Eribez, Nimisha, Mittal, Francisco-Javier, Gamo, Benigno, Crespo, Alisje, Churchyard, Irene, García-Barbazán, Jake, Baum, Marc O, Anderson, Benoît, Laleu, R Kiplin, Guy
Publikováno v:
Journal of medicinal chemistry. 63(20)
Malaria remains one of the most deadly infectious diseases, causing hundreds of thousands of deaths each year, primarily in young children and pregnant mothers. Here, we report the discovery and derivatization of a series of pyrazolo[3,4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7e9b7615d65f5856c40bca0cc86bf7b8
https://pubmed.ncbi.nlm.nih.gov/32945666
https://pubmed.ncbi.nlm.nih.gov/32945666
Autor:
Amy L. Rice, Celine DiBernardo, Jordan Bach, Tyler A Sisley, Scott Eagon, R. Kiplin Guy, Mofolusho O. Falade, Sierra D. Durham, Nikalet Everson, Joshua J. Kimball, Dylan R. Pillai, Michael J. Walls, Jared T. Hammill, Horacio Lazaro
Publikováno v:
Bioorganicmedicinal chemistry letters. 30(21)
A series of tetrahydro-β-carboline derivatives of a lead compound known to target the heat shock 90 protein of Plasmodium falciparum were synthesized and assayed for both potency against the parasite and toxicity against a human cell line. Using a r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae6e24616f77f17e1ad702d12cbcb3db
https://pubmed.ncbi.nlm.nih.gov/32822760
https://pubmed.ncbi.nlm.nih.gov/32822760
Autor:
Aashrita Manjunath, Hunter Johnson, Trevan Klug, Nathan Soderberg, Ryan Schioldager, Connor Schmid, Cameron Gleason, Scott Eagon, Horacio Lazaro, Eli O'Brien, Adam Cronin, Duminda Liyanage, Joshua J. Kimball
Publikováno v:
Tetrahedron Letters. 88:153555
A microwave mediated synthesis of 2-aminooxazoles at 150 °C was developed, providing products with a variety of functional groups. The reaction takes 5 minutes and provides product with a simple precipitation at moderate to good yields without the n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7cd651fbf98004aa3e4777d9f56fe04
https://doi.org/10.1016/j.tetlet.2021.153555
https://doi.org/10.1016/j.tetlet.2021.153555
Autor:
Jordan Bach, Scott Eagon, Kenya Yniguez, Ryan Schioldager, Lauren Loop, Nikalet Everson, Aashrita Manjunath, Megan Grabenauer, Horacio Lazaro, Briana Belanger, Grant Koch, Jarvis Law
Publikováno v:
Tetrahedron Letters. 60:72-74
A microwave-mediated synthesis of 1H-pyrazole-5-amines utilizing 1 M HCl at 150 °C was developed in order to provide products in a matter of minutes with minimal purification. Most reactions are complete in only 10 min and can be isolated via a simp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::396a39230c6c4ba7dbed65c7ea0dfca7
https://doi.org/10.1016/j.tetlet.2018.11.060
https://doi.org/10.1016/j.tetlet.2018.11.060