Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Horacio J. Novaira"'
Autor:
Silvia Capellino, Horacio J. Novaira, Sally Radovick, Fredric E. Wondisford, Andrew Schoeffield, Jon E. Levine, Ariel L Negron, Jones Bernardes Graceli, Gloria E. Hoffman, Andrew Wolfe
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 315:E1019-E1033
The effect of estrogen on the differentiation and maintenance of reproductive tissues is mediated by two nuclear estrogen receptors (ERs), ERα, and ERβ. Lack of functional ERα and ERβ genes in vivo significantly affects reproductive function; how
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d52f2adb42f6ec18ea7c7ec1fedbea07
https://doi.org/10.1152/ajpendo.00173.2018
https://doi.org/10.1152/ajpendo.00173.2018
Publikováno v:
J Vis Exp
The intestine is the home to the largest number of immune cells in the body. The small and large intestinal immune systems police exposure to exogenous antigens and modulate responses to potent microbially derived immune stimuli. For this reason, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b5afe2ec34df4f9a96fc1a8036d690a
https://pubmed.ncbi.nlm.nih.gov/31609324
https://pubmed.ncbi.nlm.nih.gov/31609324
Autor:
Horacio J. Novaira, Fredric E. Wondisford, Sally Radovick, Andrew Schoeffield, Jones Bernardes Graceli, S. Capellino, Gloria E. Hoffman, Andrew Wolfe
Publikováno v:
Endocrinology. 157:2844-2852
Estrogens regulate normal sexual and reproductive development in females. Their actions are mediated mainly by estrogen receptor (ER)α and ERβ. Understanding the function of ERs necessitates knowing their cellular location and protein partners, whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63a9c177f33a7e7cea8d8f155af5fd47
https://doi.org/10.1210/en.2016-1122
https://doi.org/10.1210/en.2016-1122
Publikováno v:
Molecular Neurobiology. 53:3315-3325
In vitro studies have demonstrated an increase in GnRH gene expression associated with an elevated secretory response to kisspeptin administration, suggesting that kisspeptin mediates GnRH expression at both the secretory and pretranslational levels.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4895f9d1866536559e7183862b4b06b5
https://doi.org/10.1007/s12035-015-9269-0
https://doi.org/10.1007/s12035-015-9269-0
Autor:
Andrew Wolfe, Mehboob A. Hussain, Prosenjit Mondal, Woo Jin Song, Horacio J. Novaira, Stephen D. Turner, Emily Farber, Owen C. Lim, Kil S. Yang, Laura C. Alonso, Benny W.T. Ong, Rachel E. Stamateris, Sally Radovick, Charles R. Farber
Publikováno v:
Cell Metabolism. 19(4):667-681
SummaryEarly in the pathogenesis of type 2 diabetes mellitus (T2DM), dysregulated glucagon secretion from pancreatic α cells occurs prior to impaired glucose-stimulated insulin secretion (GSIS) from β cells. However, whether hyperglucagonemia is ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5af3e9900e69e45da9f605156a316ce
Autor:
Sheng Wu, Dimiter Avtanski, Christopher J. Romero, Raúl M. Luque, Rhonda D. Kineman, Sally Radovick, Horacio J. Novaira, Fredric E. Wondisford
Publikováno v:
Molecular Endocrinology. 28:40-52
Although sex steroids have been implicated in the control of mammalian growth, their direct effect on GH synthesis is less clear. The aim of this study was to establish whether estradiol (E2) directly affects GH synthesis in somatotrophs. Somatotroph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4a6e3fb73e9520648900722956fb2de
https://doi.org/10.1210/me.2013-1245
https://doi.org/10.1210/me.2013-1245
Publikováno v:
Molecular and Cellular Endocrinology. 311:126-134
Kisspeptins, and their G-protein coupled receptor 54 (GPR54), are key components in the regulation of gonadotropin-releasing hormone (GnRH) secretion in humans and other mammals. Several studies demonstrate that the central or systemic administration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cbbf980d14305beb4f17e03d0dbf806
https://doi.org/10.1016/j.mce.2009.06.011
https://doi.org/10.1016/j.mce.2009.06.011
Autor:
William B. Guggino, Deepali N. Tukaye, Marcelo M. Morales, Horacio J. Novaira, Jackson Souza-Menezes
Publikováno v:
Cellular Physiology and Biochemistry. 22:093-100
TNR-CFTR, discovered as a splice variant of CFTR (Cystic Fibrosis Transmembrane conductance Regulator), is distributed in different tissues such as human and rat kidney, trachea, lungs etc and is a functional chloride channel. In Kidneys, our finding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d75b6da091775d89d8d16353aed8660
https://doi.org/10.1159/000149786
https://doi.org/10.1159/000149786
Autor:
Tania M. Ortiga-Carvalho, Horacio J. Novaira, Marcelo M. Morales, Carolina M.L. Barbosa, Debora S. Ornellas, Peying Fong, Jackson Souza-Menezes, Ana Carolina de Andrade Pinto
Publikováno v:
Cellular Physiology and Biochemistry. 20:083-090
CFTR is a multifunctional protein of the ATP binding cassette family that may contribute to overall electrolyte homeostasis by acting as a chloride channel in the kidney. In renal tissues CFTR does not exists only in its full-length form, but also as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ffa58a5f9c0eff4a011e175b56f04a0
https://doi.org/10.1159/000104156
https://doi.org/10.1159/000104156
Autor:
Gloria E. Hoffman, Sally Radovick, Kelley J. Murphy, Horacio J. Novaira, Andrew Wolfe, Sheng Wu
Publikováno v:
The FASEB Journal. 29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90ca0b5d51737bc122b3d4edb3df5014
https://doi.org/10.1096/fasebj.29.1_supplement.lb419
https://doi.org/10.1096/fasebj.29.1_supplement.lb419