Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Horacio Domene"'
Autor:
Clara Guida, Hui Sun, Mitchell B. Schaffler, Oran D. Kennedy, Jelena Basta-Pljakic, Hector G. Jasper, Shoshana Yakar, Yingjie Wu, Horacio Domene, Liliana Karabatas, Luis Cardoso, Clifford J. Rosen
Publikováno v:
Journal of Bone and Mineral Research. 28:1575-1586
States of growth hormone (GH) resistance, such those observed in Laron dwarf patients, are characterized by mutations in the GH receptor (GHR), decreased serum and tissue IGF-1 levels, impaired glucose tolerance, and impaired skeletal acquisition. IG
Autor:
Horacio Domene, María Gabriela Ropelato, Rodolfo Rey, Alicia Martínez, Silvia Gottlieb, Ana Keselman, María Gabriela Ballerini, Romina P Grinspon
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 95:2811-2818
Context: Differential diagnosis between hypogonadotropic hypogonadism (HH) and constitutional delay of puberty in boys is challenging. Most tests use an acute GnRH stimulus, allowing only the release of previously synthesized gonadotropins. A constan
Autor:
Naseem Malik, Juan J. Heinrich, Ana Chiesa, Jean-Marc Vuissoz, Horacio Domene, Johnny Deladoëy, Laura Gruñeiro-Papendieck, Primus E. Mullis
Publikováno v:
Thyroid. 13:553-559
We identified five patients with congenital secondary hypothyroidism with isolated thyrotropin (TSH) deficiency originating from three and two unrelated Argentinean and Swiss families, respectively. The affected patients presented with both low TSH a
Autor:
Alicia Martínez, Patricia Pennisi, M E Escobar, Hector Jasper, M. Gabriela Ropelato, Horacio Domene, Juan J. Heinrich
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 85:4168-4172
We have studied the effect of estradiol (E2)on the GH-insulin-like growth factor (GH-IGF) axis in 15 prepubertal GH deficiency (GHD) children and 44 prepubertal or early pubertal children with idiopathic short stature (SS). All of them received a dai
Autor:
Horacio Domene, R. Rey, S. Bengolea, Martinez A, H. Jasper, Pipman, Keselman A, Ropelato M G, Ballerini M G, J. Heinrich, Scaglia R
Publikováno v:
Ожирение и метаболизм, Vol 8, Iss 4 (2011)
Autor:
Luis Cardoso, Hui Sun, Jan Frystyk, Hayden William Courtland, Liliana Karabatas, Chengyu Liu, Sebastien Elis, Jelena Basta-Pljakic, Shoshana Yakar, Mordechay Beth-On, Hector Jasper, Yingjie Wu, Clifford J. Rosen, Horacio Domene, Dara Cannata, Clara Guida
Publikováno v:
Elis, S, Wu, Y, Courtland, H-W, Cannata, D, Sun, H, Beth-On, M, Liu, C, Jasper, H, Domené, H, Karabatas, L, Guida, C, Basta-Pljakic, J, Cardoso, L, Rosen, C J, Frystyk, J & Yakar, S 2011, ' Unbound (bioavailable) IGF1 enhances somatic growth ', Disease Models and Mechanisms, vol. 4, no. 5, pp. 649-58 . https://doi.org/10.1242/dmm.006775
Disease Models & Mechanisms
Disease Models & Mechanisms, Cambridge Company of Biologists, 2011, 4 (5), pp.649-658. ⟨10.1242/dmm.006775⟩
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Disease Models and Mechanisms 5 (4), 649-658. (2011)
Disease Models & Mechanisms, Vol 4, Iss 5, Pp 649-658 (2011)
Disease Models & Mechanisms
Disease Models & Mechanisms, Cambridge Company of Biologists, 2011, 4 (5), pp.649-658. ⟨10.1242/dmm.006775⟩
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Disease Models and Mechanisms 5 (4), 649-658. (2011)
Disease Models & Mechanisms, Vol 4, Iss 5, Pp 649-658 (2011)
Understanding insulin-like growth factor-1 (IGF1) biology is of particular importance because, apart from its role in mediating growth, it plays key roles in cellular transformation, organ regeneration, immune function, development of the musculoskel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a330c66aae55d6f63bb78ba11cd6836
https://pure.au.dk/portal/da/publications/unbound-bioavailable-igf1-enhances-somatic-growth(3ce07b3a-f2cf-4047-b28f-c726071bc520).html
https://pure.au.dk/portal/da/publications/unbound-bioavailable-igf1-enhances-somatic-growth(3ce07b3a-f2cf-4047-b28f-c726071bc520).html
Autor:
Laurie E. Cohen, Jesús Pozo, Peter Bang, Gabriele Haeusler, Jan M. Wit, Hector G. Jasper, Catherine Pihoker, Jesús Argente, Elena Gallego-Gomez, Angel Campos-Barros, Christina Jacobsen, Ron G. Rosenfeld, Hermine A. van Duyvenvoorde, Wolfgang Högler, Susan Kirsch, Ricardo Gracia-Bouthelier, Horacio Domene, Vivian Hwa, Harvey K. Chiu, Olga V. Fofanova-Gambetti
Publikováno v:
Journal of Clinical Endocrinology and Metabolism, 95(9), 4184-4191
Context: To date, 16 IGFALS mutations in 21 patients with acid-labile subunit (ALS) deficiency have been reported. The impact of heterozygosity for IGFALS mutations on growth is unknown. Objective: The study evaluates the impact of heterozygous expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f87d1498128dcbfb4d55a2c630ab595
https://hdl.handle.net/1887/110452
https://hdl.handle.net/1887/110452
Autor:
Jan Frystyk, Mariana Gutierrez, Salman Kirmani, Hector Jasper, Aida N. Lteif, Patricia Bedecarrás, Farid H. Mahmud, Horacio Domene, Paula Scaglia
Publikováno v:
The Journal of clinical endocrinology and metabolism. 92(11)
IGF-I deficiency may result from impairment of GH secretion or action, or from defects in IGF-I synthesis, transport, or action. Complete deficiency of the acid-labile subunit (ALS), previously described in two male patients, the only known inherited
Autor:
Sonia Bengolea, Jian-Wen Chen, Alicia Martínez, Jan Frystyk, Hector Jasper, Horacio Domene, Paula Scaglia, Juan J. Heinrich, Ole D. Wolthers, Carsten Heuck, María Gabriela Ropelato
Publikováno v:
Domené, H M, Martínez, A S, Frystyk, J, Bengolea, S V, Ropelato, M G, Scaglia, P A, Chen, J-W, Heuck, C, Wolthers, O D, Heinrich, J J & Jasper, H G 2007, ' Normal growth spurt and final height despite low levels of all forms of circulating insulin-like growth factor-I in a patient with acid-labile subunit deficiency. ', Hormone Research, vol. 67, no. 5, pp. 243-9 . https://doi.org/10.1159/000098479
Background: In a recently described patient with acid-labile subunit (ALS) deficiency, the inability to form ternary complexes resulted in a marked reduction in circulating total insulin-like growth factor (IGF)-I, whereas skeletal growth was only ma