Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Hope Needham"'
Autor:
Panagiotis A. Konstantinopoulos, Niya Xiong, Carolyn Krasner, Joyce F. Liu, Hannah Sawyer, Madeline Polak, Hope Needham, Megan Geddes, Lani Koppermann, Meghan Shea, Cesar Castro, Su-Chun Cheng, Ursula A. Matulonis, Elizabeth K. Lee
Publikováno v:
Gynecologic Oncology Reports, Vol 52, Iss , Pp 101348- (2024)
Several lines of preclinical evidence indicate that combining PI3K and CDK4/6 inhibitors may further enhance the efficacy of hormonal therapy by overcoming de novo and acquired resistance to PI3K and CDK4/6 blockade. We evaluated the combination of a
Externí odkaz:
https://doaj.org/article/a58a03d3330d4b9d9bd8d84d99a74acc
Autor:
Hope Needham, Grace Torpey, Carlos C. Flores, Christopher J. Davis, William M. Vanderheyden, Jason R. Gerstner
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Fatty acid binding proteins (FABPs) are a family of intracellular lipid chaperone proteins known to play critical roles in the regulation of fatty acid uptake and transport as well as gene expression. Brain-type fatty acid binding protein (FABP7) is
Externí odkaz:
https://doaj.org/article/d03fa62519b34b85a599cd9e3d6810db
Autor:
Panagiotis A. Konstantinopoulos, Elizabeth K. Lee, Niya Xiong, Carolyn Krasner, Susana Campos, David L. Kolin, Joyce F. Liu, Neil Horowitz, Alexi A. Wright, Sara Bouberhan, Richard T. Penson, Oladapo Yeku, Brittany Bowes, Hope Needham, Martin Hayes, Hannah Sawyer, Madeline Polak, Meghan Shea, Su-Chun Cheng, Cesar Castro, Ursula A. Matulonis
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
PURPOSE Estrogen receptor (ER)–positive endometrial cancers (ECs) are characterized by phosphatidylinositol 3-kinase (PI3K) and receptor tyrosine kinase (RTK)/RAS/β-catenin (CTNNB1) pathway alterations in approximately 90% and 80% of cases, respec