Výsledky vyhledávání - "Hooymans, P. M."

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Morphometric analyses of the visual pathways in macular degeneration

Autor: Hernowo, Aditya T., Prins, Doety, Baseler, Heidi A., Plank, Tina, Gouws, Andre, Hooymans, Johanna M. M., Morland, Antony B., Greenlee, Mark W., Cornelissen, Frans W.

Introduction. Macular degeneration (MD) causes central visual field loss. When field defects occur in both eyes and overlap, parts of the visual pathways are no longer stimulated. Previous reports have shown that this affects the grey matter of the p

Externí odkaz: http://arxiv.org/abs/1501.05391

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The glutathione transferase Mu null genotype leads to lower 6-MMPR levels in patients treated with azathioprine but not with mercaptopurine

Autor: Broekman, M M T J, Wong, D R, Wanten, G J A, Roelofs, H M, van Marrewijk, C J, Klungel, O H, Verbeek, A L M, Hooymans, P M, Guchelaar, H-J, Scheffer, H, Derijks, L J J, Coenen, M J H, de Jong, D J

The conversion of azathioprine (AZA) to mercaptopurine (MP) is mediated by glutathione transferase Mu1 (GSTM1), alpha1 (GSTA1) and alpha2 (GSTA2). We designed a case-control study with data from the TOPIC trial to explore the effects of genetic varia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______101::18fa247c7726e9689f4ab8a01d7d9b1b
https://dspace.library.uu.nl/handle/1874/375235

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Akademický článek

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Early prediction of thiopurine-induced hepatotoxicity in inflammatory bowel disease

Autor: Wong, D R, Coenen, M J H, Derijks, L J J, Vermeulen, S H, van Marrewijk, Corine J, Klungel, O H, Scheffer, H, Franke, B, Guchelaar, H-J, de Jong, Dirk J., Engels, L G J B, Verbeek, A.L., Hooymans, P M, Afd Pharmacoepi & Clinical Pharmacology, Pharmacoepidemiology and Clinical Pharmacology

Publikováno v: Alimentary Pharmacology & Therapeutics, 45(3), 391-402. Wiley
Alimentary Pharmacology & Therapeutics, 45, 3, pp. 391-402
Alimentary Pharmacology & Therapeutics, 45(3), 391. Wiley-Blackwell
Alimentary Pharmacology and Therapeutics, 45(3), 391-402
Alimentary Pharmacology and Therapeutics, 45(3), 391. Wiley-Blackwell
Alimentary Pharmacology & Therapeutics, 45, 391-402

Contains fulltext : 169966.pdf (Publisher’s version ) (Closed access) BACKGROUND: Hepatotoxicity, gastrointestinal complaints and general malaise are common limiting adverse reactions of azathioprine and mercaptopurine in IBD patients, often relate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90f213ead12f93dc042a14238ff91c22
https://cris.maastrichtuniversity.nl/en/publications/86066f25-a222-4a52-8d27-76358e5f09a3

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