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Identification of Drug Transporter Genomic Variants and Inhibitors That Protect Against Doxorubicin-Induced Cardiotoxicity

Autor: Tarek Magdy, Mariam Jouni, Hui-Hsuan Kuo, Carly J. Weddle, Davi Lyra-Leite, Hananeh Fonoudi, Marisol Romero-Tejeda, Mennat Gharib, Hoor Javed, Giovanni Fajardo, Colin J.D. Ross, Bruce C. Carleton, Daniel Bernstein, Paul W. Burridge

Publikováno v: Circulation. 145:279-294

Background: Multiple pharmacogenomic studies have identified the synonymous genomic variant rs7853758 (G > A, L461L) and the intronic variant rs885004 in SLC28A3 (solute carrier family 28 member 3) as statistically associated with a lower incidence o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f2e1d7d7e9fec71b08d4f4bc1a69b7a
https://doi.org/10.1161/circulationaha.121.055801

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