Supramolecular Cylinders Target Bulge Structures in the 5' UTR of the RNA Genome of SARS-CoV-2 and Inhibit Viral Replication*.

Autor: Melidis L; Physical Sciences for Health Centre, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK., Hill HJ; Institute of Immunology and Immunotherapy, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK., Coltman NJ; School of Biosciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK., Davies SP; Institute of Immunology and Immunotherapy, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK., Winczura K; School of Biosciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK., Chauhan T; Physical Sciences for Health Centre, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK., Craig JS; Physical Sciences for Health Centre, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK., Garai A; School of Chemistry, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK., Hooper CAJ; School of Chemistry, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK., Egan RT; School of Chemistry, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK., McKeating JA; Nuffield Department of Medicine & Chinese Academy of Medical Sciences (CAMS) Oxford Institute (COI), Oxford University, Oxford, OX3 7BN, UK., Hodges NJ; School of Biosciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK., Stamataki Z; Institute of Immunology and Immunotherapy, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK., Grzechnik P; School of Biosciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK., Hannon MJ; Physical Sciences for Health Centre, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.; School of Chemistry, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.

Publikováno v: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2021 Aug 09; Vol. 60 (33), pp. 18144-18151. Date of Electronic Publication: 2021 Jul 09.

Rotaxanating Metallo-supramolecular Nano-cylinder Helicates to Switch DNA Junction Binding.

Autor: Hooper CAJ; School of Chemistry, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom., Cardo L; School of Chemistry, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom., Craig JS; Physical Sciences for Health Centre, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom., Melidis L; Physical Sciences for Health Centre, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom., Garai A; School of Chemistry, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom., Egan RT; School of Chemistry, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom., Sadovnikova V; School of Chemistry, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom., Burkert F; School of Chemistry, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom., Male L; School of Chemistry, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom., Hodges NJ; School of Biosciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom., Browning DF; School of Biosciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom., Rosas R; Aix Marseille Univ, CNRS, Centrale Marseille, FSCM, Spectropole, Marseille 13007, France., Liu F; The State Key Laboratory of Refractories and Metallurgy, School of Chemistry and Chemical Engineering, Wuhan University of Science and Technology, Wuhan 430081, P. R. China., Rocha FV; Department of Chemistry, Federal University of São Carlos, São Carlos 13565-905, Brazil., Lima MA; Department of Chemistry, Federal University of São Carlos, São Carlos 13565-905, Brazil., Liu S; The State Key Laboratory of Refractories and Metallurgy, School of Chemistry and Chemical Engineering, Wuhan University of Science and Technology, Wuhan 430081, P. R. China., Bardelang D; Aix Marseille Univ, CNRS, ICR, Marseille 13013, France., Hannon MJ; School of Chemistry, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom.; Physical Sciences for Health Centre, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom.

Publikováno v: Journal of the American Chemical Society [J Am Chem Soc] 2020 Dec 09; Vol. 142 (49), pp. 20651-20660. Date of Electronic Publication: 2020 Nov 20.