Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Hoonsik Cho"'
Autor:
Quanjiang Ji, Peter J. Chen, Guangrong Qin, Xin Deng, Ziyang Hao, Zdzislaw Wawrzak, Won-Sik Yeo, Jenny Winjing Quang, Hoonsik Cho, Guan-Zheng Luo, Xiaocheng Weng, Qiancheng You, Chi-Hao Luan, Xiaojing Yang, Taeok Bae, Kunqian Yu, Hualiang Jiang, Chuan He
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
The WalKR signal transduction system is involved in extracellular signal recognition, but the details of this function are not well established. Here, the authors report the crystal structure of this two-component system alongside the characterisatio
Externí odkaz:
https://doaj.org/article/982278f7c02745b09c2db25ee3867b43
Autor:
Hoonsik Cho, Do-Won Jeong, Qian Liu, Won-Sik Yeo, Thomas Vogl, Eric P Skaar, Walter J Chazin, Taeok Bae
Publikováno v:
PLoS Pathogens, Vol 11, Iss 7, p e1005026 (2015)
Calprotectin, the most abundant cytoplasmic protein in neutrophils, suppresses the growth of Staphylococcus aureus by sequestering the nutrient metal ions Zn and Mn. Here we show that calprotectin can also enhance the activity of the SaeRS two compon
Externí odkaz:
https://doaj.org/article/349ff11bb06640ceb144321bf27eab97
Publikováno v:
PLoS Pathogens, Vol 11, Iss 4, p e1004799 (2015)
Bacterial pathogens often employ two-component systems (TCSs), typically consisting of a sensor kinase and a response regulator, to control expression of a set of virulence genes in response to changing host environments. In Staphylococcus aureus, th
Externí odkaz:
https://doaj.org/article/f6eadff4bb9e414897d22592042ac700
Autor:
Quanjiang Ji, Peter J. Chen, Guangrong Qin, Xin Deng, Ziyang Hao, Zdzislaw Wawrzak, Won-sik Yeo, Jenny Winjing Quang, Hoonsik Cho, Guan-Zheng Luo, Xiaocheng Weng, Qiancheng You, Chi-Hao Luan, Xiaojing Yang, Taeok Bae, Kunqian Yu, Hualiang Jiang, Chuan He
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-1 (2017)
Nature Communications 7: Article number:11000 (2016); Published 18 March 2016: Updated 6 February 2017 In this Article, we presented a structural and functional characterization of the WalKR two-component system for signal transduction and a small mo
Externí odkaz:
https://doaj.org/article/2233302e69b14a45af7c67bc327b8c11
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15703 (2010)
Recently, dipeptide aureusimines were reported to activate expression of staphylococcal virulence genes, such as alpha-hemolysin, and increase S. aureus virulence. Surprisingly, most of the virulence genes affected by aureusimines form part of the re
Externí odkaz:
https://doaj.org/article/1c5372913f4f49c5a14a2eb1077b5332
Autor:
Guan Zheng Luo, Jenny Winjing Quang, Quanjiang Ji, Hoonsik Cho, Taeok Bae, Kunqian Yu, Qiancheng You, Guangrong Qin, Xiaocheng Weng, Xin Deng, Peter J. Chen, Zdzislaw Wawrzak, Ziyang Hao, Won Sik Yeo, Chi Hao Luan, Xiaojing Yang, Hualiang Jiang, Chuan He
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-1 (2017)
Nature Communications, Vol 8, Iss 1, Pp 1-1 (2017)
Most low GC Gram-positive bacteria possess an essential walKR two-component system (TCS) for signal transduction involved in regulating cell wall homoeostasis. Despite the well-established intracellular regulatory mechanism, the role of this TCS in e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fbc18519bae13a6e80b4f391584fa0f
https://doi.org/10.1038/ncomms14331
https://doi.org/10.1038/ncomms14331
Autor:
Zdzislaw Wawrzak, Jenny Winjing Quang, Kunqian Yu, Peter J. Chen, Xiaojing Yang, Guangrong Qin, Chuan He, Won Sik Yeo, Hoonsik Cho, Taeok Bae, Guan Zheng Luo, Ziyang Hao, Xiaocheng Weng, Chi Hao Luan, Quanjiang Ji, Hualiang Jiang, Qiancheng You, Xin Deng
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Nature Communications
Nature Communications
Most low GC Gram-positive bacteria possess an essential walKR two-component system (TCS) for signal transduction involved in regulating cell wall homoeostasis. Despite the well-established intracellular regulatory mechanism, the role of this TCS in e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38779fbe4618074f4ba7596ae36446b5
https://doi.org/10.1038/ncomms11000
https://doi.org/10.1038/ncomms11000
Publikováno v:
The Journal of Immunology. 189:4787-4796
H2-M3–restricted T cells have a preactivated surface phenotype, rapidly expand, and produce cytokines upon stimulation, and, as such, are classified as innate T cells. Unlike most innate T cells, M3-restricted T cells also express CD8αβ corecepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c005149a3bc57bb27c8d6eb42aba69d
https://doi.org/10.4049/jimmunol.1200579
https://doi.org/10.4049/jimmunol.1200579
Autor:
Chuan He, Marcus B. Jones, Kenneth Shatzkes, Do Won Jeong, Taeok Bae, Quanjiang Ji, Qian Liu, Scott N. Peterson, Fei Sun, Hoonsik Cho
Publikováno v:
Molecular Microbiology. 86:331-348
In bacterial two-component regulatory systems (TCSs), dephosphorylation of phosphorylated response regulators is essential for resetting the activated systems to the pre-activation state. However, in the SaeRS TCS, a major virulence TCS of Staphyloco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8ba62ac95b2935b6e258c3a55f85cbd
https://doi.org/10.1111/j.1365-2958.2012.08198.x
https://doi.org/10.1111/j.1365-2958.2012.08198.x
Autor:
Leslie M. Hicks, Sherrie Xie, Xiangqian Kong, Haiyan Zhang, Taeok Bae, Chuan He, Quanjiang Ji, Xin Deng, Hualiang Jiang, Haihua Liang, Fei Sun, Sophie Alvarez, Hoonsik Cho, Cheng Luo
Publikováno v:
Proceedings of the National Academy of Sciences. 109:9095-9100
Oxidation sensing and quorum sensing significantly affect bacterial physiology and host–pathogen interactions. However, little attention has been paid to the cross-talk between these two seemingly orthogonal signaling pathways. Here we show that th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d67e3110dab9749c70c962558e9234cc
https://doi.org/10.1073/pnas.1200603109
https://doi.org/10.1073/pnas.1200603109