Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Hoong Chuin, Lim"'
Publikováno v:
mBio, Vol 12, Iss 3 (2021)
The Corynebacterineae
Externí odkaz:
https://doaj.org/article/213ab4ab0dc145978f1c5730178607e5
Publikováno v:
eLife, Vol 9 (2020)
Members of the Corynebacterineae suborder of Actinobacteria have a unique cell surface architecture and, unlike most well-studied bacteria, grow by tip-extension. To investigate the distinct morphogenic mechanisms shared by these organisms, we perfor
Externí odkaz:
https://doaj.org/article/6279c6f82552406fb15eb30355933fca
Autor:
Hoong Chuin Lim, Joel W Sher, Frances P Rodriguez-Rivera, Coralie Fumeaux, Carolyn R Bertozzi, Thomas G Bernhardt
Publikováno v:
PLoS Genetics, Vol 15, Iss 8, p e1008284 (2019)
Several important human pathogens are represented in the Corynebacterineae suborder, including Mycobacterium tuberculosis and Corynebacterium diphtheriae. These bacteria are surrounded by a multilayered cell envelope composed of a cytoplasmic membran
Externí odkaz:
https://doaj.org/article/504315a977924ac69705e989bad6664c
Autor:
Catherine Baranowski, Michael A Welsh, Lok-To Sham, Haig A Eskandarian, Hoong Chuin Lim, Karen J Kieser, Jeffrey C Wagner, John D McKinney, Georg E Fantner, Thomas R Ioerger, Suzanne Walker, Thomas G Bernhardt, Eric J Rubin, E Hesper Rego
Publikováno v:
eLife, Vol 7 (2018)
In most well-studied rod-shaped bacteria, peptidoglycan is primarily crosslinked by penicillin-binding proteins (PBPs). However, in mycobacteria, crosslinks formed by L,D-transpeptidases (LDTs) are highly abundant. To elucidate the role of these unus
Externí odkaz:
https://doaj.org/article/6695fdf7fa9f4cceb2741307353a71cf
Autor:
Alam García-Heredia, Amol Arunrao Pohane, Emily S Melzer, Caleb R Carr, Taylor J Fiolek, Sarah R Rundell, Hoong Chuin Lim, Jeffrey C Wagner, Yasu S Morita, Benjamin M Swarts, M Sloan Siegrist
Publikováno v:
eLife, Vol 7 (2018)
Rod-shaped mycobacteria expand from their poles, yet d-amino acid probes label cell wall peptidoglycan in this genus at both the poles and sidewall. We sought to clarify the metabolic fates of these probes. Monopeptide incorporation was decreased by
Externí odkaz:
https://doaj.org/article/d8126d86165d48daa68baa4773114a87
Publikováno v:
PLoS Genetics, Vol 13, Iss 7, p e1006908 (2017)
Successive division events in the spherically shaped bacterium Staphylococcus aureus are oriented in three alternating perpendicular planes. The mechanisms that underlie this relatively unique pattern of division and coordinate it with chromosome seg
Externí odkaz:
https://doaj.org/article/8c79858ea6dd4534b4056da43a242fe9
Autor:
Alexander J Meeske, Christopher D A Rodrigues, Jacqueline Brady, Hoong Chuin Lim, Thomas G Bernhardt, David Z Rudner
Publikováno v:
PLoS Biology, Vol 14, Iss 1, p e1002341 (2016)
The differentiation of the bacterium Bacillus subtilis into a dormant spore is among the most well-characterized developmental pathways in biology. Classical genetic screens performed over the past half century identified scores of factors involved i
Externí odkaz:
https://doaj.org/article/8600f8d59f384a9e8ee133b9b4204e0b
Autor:
Hoong Chuin Lim, Thomas G. Bernhardt
Publikováno v:
Mol Microbiol
Most bacteria are surrounded by a complex cell envelope. As with many biological processes, studies of envelope assembly have benefited from cell-based assays for detecting protein-protein interactions. These assays use simple readouts and lack a pro
Autor:
Carolyn R. Bertozzi, Xiaoxue Zhou, Julie A. Theriot, Thomas G. Bernhardt, Hoong Chuin Lim, Frances P. Rodriguez-Rivera, Jason C. Bell
Publikováno v:
Nature Chemical Biology. 15:221-231
Members of the Corynebacterineae, including Corynebacterium and Mycobacterium, have an atypical cell envelope characterized by an additional mycomembrane outside of the peptidoglycan layer. How this multilayered cell envelope is assembled remains unc
Autor:
Hoong Chuin Lim, Ivan Vladimirovich Surovtsev, Bruno Gabriel Beltran, Fang Huang, Jörg Bewersdorf, Christine Jacobs-Wagner
Publikováno v:
eLife, Vol 3 (2014)
The widely conserved ParABS system plays a major role in bacterial chromosome segregation. How the components of this system work together to generate translocation force and directional motion remains uncertain. Here, we combine biochemical approach
Externí odkaz:
https://doaj.org/article/8382d710a2154f7199553491e7ba7859