Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Hoon Jae Jeong"'
Autor:
Mi Jin Kim, Hoon Jae Jeong, Dae Won Kim, Eun Jeong Sohn, Hyo Sang Jo, Duk-Soo Kim, Hyun Ah Kim, Eun Young Park, Jong Hoon Park, Ora Son, Kyu Hyung Han, Jinseu Park, Won Sik Eum, Soo Young Choi
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86034 (2014)
Paraoxonase 1 (PON1) is an antioxidant enzyme which plays a central role in various diseases. However, the mechanism and function of PON1 protein in inflammation are poorly understood. Since PON1 protein alone cannot be delivered into cells, we gener
Externí odkaz:
https://doaj.org/article/4fcab1c9b34a488a8f2b8fcd5f1b162b
Autor:
Hoon Jae Jeong, In Koo Hwang, Sung Min Nam, Jong Hwi Kim, Hyo Young Jung, Jung Hoon Choi, Seung Myung Moon, Soo Young Choi, Dae Young Yoo, Moo Ho Won, Dae-Won Kim, Woosuk Kim, Yeo Sung Yoon
Publikováno v:
Neurochemical Research. 39:187-193
The DJ-1 gene is highly conserved in diverse species and DJ-1 is known as an anti-oxidative stress factor. In this study, we investigated the neuroprotective effects of DJ-1 against ischemic damage in the rabbit spinal cord. Tat-DJ-1 fusion proteins
Autor:
Hoon Jae Jeong, Jong Hwi Kim, Jung Hoon Choi, Dae Won Kim, In Koo Hwang, Soo Young Choi, Woosuk Kim, Dae Young Yoo, Yeo Sung Yoon, Sung Min Nam, Hyo Young Jung
Publikováno v:
Neurochemical Research. 38:2046-2055
Oxidative stress initiates age-related reduction in hippocampal neurogenesis and the use of antioxidants has been proposed as an effective strategy to prevent or attenuate the reduction of neurogenesis in the hippocampus. In the present study, we inv
Autor:
Sung-Woo Cho, Yeom Pyo Lee, Tae-Cheon Kang, Soo Young Choi, Mi Jin Kim, Hoon Jae Jeong, Duk-Soo Kim, Jae Hyeok Hwang, Eun Hee Ahn, Oh-Shin Kwon, Eun Jeong Sohn, Hye Won Kang, Jinseu Park, Dae Won Kim, Won Sik Eum, Min Jea Shin
Publikováno v:
FEBS Journal. 279:1929-1942
Heat shock proteins (HSPs) are a highly conserved family of proteins that are induced in response to various environmental stressors including reactive oxygen species. HSP27 is a chaperone protein with the ability to increase cell survival in respons
Autor:
Soo Young Choi, Joon Kim, Dae Won Kim, Moo Ho Won, Eun Jeong Sohn, Sung-Woo Cho, Hoon Jae Jeong, Min Jung Lee, Soon Won Kwon, Won Sik Eum, Hye Won Kang, Young Nam Kim, Tae-Cheon Kang, Min Jea Shin, Kyu Hyung Han, Eun Hee Ahn, Jinseu Park
Publikováno v:
Life Sciences. 89:896-904
Aims Cyclophilin A (CypA) is an immunophilin that acts as a receptor for the immunosuppressant drug cyclosporine A (CsA). CypA has emerged as a potential drug target for several inflammatory diseases, although the details of its mechanism are unclear
Autor:
Sung-Woo Cho, Hoon Jae Jeong, Mi Jin Kim, Dae Won Kim, Jinseu Park, Duk-Soo Kim, Soon Sung Lim, Eun Jeong Sohn, Won Sik Eum, Hyun Sook Hwang, Suman Dutta, Soon Won Kwon, Eun Hee Ahn, Soo Young Choi, Kil Soo Lee
Publikováno v:
BMB Reports. 44:647-652
The protein transduction domains have been reported to have potential to deliver the exogenous molecules, including proteins, to living cells. However, poor transduction of proteins limits therapeutic application. In this study, we examined whether i
Autor:
Hoon Jae Jeong, Suman Dutta, Dae Won Kim, Eun Jeong Sohn, Duk-Soo Kim, Young Nam Kim, Hyun Sook Hwang, Soon Won Kwon, Jinseu Park, Eun Hee Ahn, Mi Jin Kim, Won Sik Eum, Soo Young Choi
Publikováno v:
Biochemical and Biophysical Research Communications. 411:354-359
Highlights: {yields} Recombinant PEP-1 heme oxygenase-1 expression vector was constructed and overexpressed. {yields} We investigated transduction efficiency of PEP-1-HO-1 protein in Raw 264.7 cells. {yields} PEP-1-HO-1 was efficiently transduced int
Autor:
Tae-Cheon Kang, Dae-Won Kim, Kil Soo Lee, Hoon Jae Jeong, Jinseu Park, Duk Soo Kim, Soo Young Choi, Eun Jeong Sohn, Sung-Woo Cho, Mi Jin Kim, Il Jun Kang, Soon Sung Lim, Sun Hwa Lee, Won Sik Eum
Publikováno v:
BMB Reports. 43:561-566
Though protein transduction domains (PTDs) are well known for the delivery of exogenous therapeutic proteins into living cells, the overall low efficiency of transduction is a serious obstacle. We investigated the effect of bog blueberry anthocyanins
Autor:
In Koo Hwang, Moo Ho Won, Jae Jin An, Ki-Yeon Yoo, Kil Soo Lee, Sun Hwa Lee, Min Seop Jeong, Won Sik Eum, Sung-Woo Cho, Sang Ho Jang, Eun Jeong Sohn, Mi Jin Kim, Hoon Jae Jeong, Dae Won Kim, Soo Young Choi, Jinseu Park, Tae-Cheon Kang
Publikováno v:
Free Radical Biology and Medicine. 48:969-977
Reactive oxygen species (ROS) have been implicated in the pathogenesis of ischemic brain injury. Sensitive to apoptosis gene (SAG) is a RING-finger protein that exhibits antioxidant activity against a variety of redox reagents. However, the protectiv
Autor:
Jae Jin An, Moo Ho Won, Tae-Cheon Kang, Won Sik Eum, Dae Won Kim, Oh-Shin Kwon, In Koo Hwang, Eun Jeong Sohn, Sung-Woo Cho, Hye Won Kang, Ki-Yeon Yoo, Hoon Jae Jeong, Eun Hee Ahn, Min Jea Shin, Jinseu Park, Soo Young Choi, Sang Ho Jang, Mi Jin Kim
Publikováno v:
Free Radical Biology and Medicine. 47:941-952
Antioxidant enzymes are considered to have beneficial effects against various diseases mediated by reactive oxygen species (ROS). Ischemia is characterized by both oxidative stress and changes in the antioxidant defense system. Catalase (CAT) and sup