Zobrazeno 1 - 10
of 337
pro vyhledávání: '"Hoon Chul Kang"'
Autor:
Eul Sik Jung, Ji Hun Kim, Mi-Yoon Chang, Wonjun Hong, Zhejiu Quan, Seung Hyun Kim, Seungkwon You, Dae-Sung Kim, Jiho Jang, Sang-Hun Lee, Hyongbum Henry Kim, Hoon Chul Kang
Publikováno v:
Stem Cell Research, Vol 59, Iss , Pp 102664- (2022)
X-linked adrenoleukodystrophy (ALD) caused by the ABCD1 mutation, is the most common inherited peroxisomal disease. Previously, we generated an ALD patient-derived SCHi001-A iPSC model. In this study, we have performed the first genome editing of ALD
Externí odkaz:
https://doaj.org/article/5d11b80c4cb347fb883062844b1ab6e8
Autor:
Sangbo Lee, Ara Ko, In Sook Sol, Kyung Won Kim, Hoon Chul Kang, Joon Soo Lee, Heung Dong Kim, Se Hee Kim
Publikováno v:
Annals of Child Neurology, Vol 27, Iss 1, Pp 13-21 (2019)
Purpose Electroencephalography (EEG) is an effective test in predicting severe cortical dysfunction associated with poor outcomes in adult patients, but its value in pediatric patients remains incomplete. Here, we assessed the prognostic value of EEG
Externí odkaz:
https://doaj.org/article/a01939179781418f9ec8b053e3da6447
Autor:
Daeahn Cho, Myeong-Sang Yu, Jeongyoon Shin, Jingyu Lee, Yubin Kim, Hoon-Chul Kang, Se Hee Kim, Dokyun Na
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 24, Iss S2, Pp 1-9 (2024)
Abstract Background Epilepsy, a chronic brain disorder characterized by abnormal brain activity that causes seizures and other symptoms, is typically treated using anti-epileptic drugs (AEDs) as the first-line therapy. However, due to the variations
Externí odkaz:
https://doaj.org/article/46bc8951cf4c4a839acfdfc13e3e88e4
Publikováno v:
Korean Journal of Pediatrics, Vol 54, Iss 1, Pp 22-28 (2011)
PurposeTo investigate the clinical characteristics of late-onset epilepsy combined with autism spectrum disorder (ASD), and the relationship between certain types of electroencephalography (EEG) abnormalities in ASD and associated neuropsychological
Externí odkaz:
https://doaj.org/article/b7a3bd82853a430c9f064164b5561450
Autor:
Jung Hyun Chae, Jung Hun Lee, Kyo Ryung Kim, Suk Ho Byeon, Young Mock Lee, Hoon Chul Kang, Joon Soo Lee, Heung Dong Kim
Publikováno v:
Korean Journal of Pediatrics, Vol 53, Iss 12, Pp 994-999 (2010)
PurposeMitochondrial dysfunction can present with various symptoms depending on the organ it has affected. This research tried to analyze the ophthalmologic symptoms and ophthalmologic examination (OE) results in patients with mitochondrial disease (
Externí odkaz:
https://doaj.org/article/1f31bb9c5113427daabd0abcab36a367
Publikováno v:
Korean Journal of Pediatrics, Vol 53, Iss 5, Pp 644-647 (2010)
PurposeTo evaluate myocardial conductivity to understand cardiac involvement in patients with mitochondrial disease.MethodsWe performed retrospective study on fifty-seven nonspecific mitochondrial encephalopathy patients with no clinical cardiac mani
Externí odkaz:
https://doaj.org/article/d22a8ade247942fbbb8c5785e700950b
Publikováno v:
Korean Journal of Pediatrics, Vol 53, Iss 2, Pp 163-166 (2010)
Purpose : Leigh syndrome is a typical type of mitochondrial disease. This study was conducted to analyze the types of ophthalmologic symptoms and results of funduscopy conducted in the ophthalmologic examination of patients with Leigh syndrome. Metho
Externí odkaz:
https://doaj.org/article/8fdb88cd17aa47979c363c8b43f43dc3
Autor:
Soyoung Park, Hye Eun Kwon, Chung Mo Koo, Yun Jung Hur, Hoon-Chul Kang, Joon Soo Lee, Heung Dong Kim
Publikováno v:
Annals of Child Neurology, Vol 32, Iss 1, Pp 13-20 (2024)
Purpose This study examined the characteristics and outcomes of resective epilepsy surgery following corpus callosotomy (CC) in children with Lennox-Gastaut syndrome (LGS). Methods We retrospectively analyzed 17 children with LGS who underwent resect
Externí odkaz:
https://doaj.org/article/3d103029c19242229177680e3e4c018f
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract This study determined the 24-month outcomes of perampanel treatment in children and adolescents with epilepsy. The percentage of ≥ 50% responders was 47.3% (139/294) at 12 months and 49.0% (144/294) at 24 months. A 100% reduction in seizur
Externí odkaz:
https://doaj.org/article/38574e96024141f292977da9741a4de3
Publikováno v:
Annals of Child Neurology, Vol 31, Iss 2, Pp 91-96 (2023)
Purpose Lamotrigine (LTG) is often used as adjunctive therapy in Lennox-Gastaut syndrome (LGS); however, it may worsen myoclonic and atypical absence seizures in LGS patients. This study reviewed the overall efficacy and safety of LTG in children wit
Externí odkaz:
https://doaj.org/article/208445f513a94b3a9aac7a724a86ae1a