Zobrazeno 1 - 10 of 213 pro vyhledávání: '"Hook LM"'
1
Akademický článek
A Trivalent HSV-2 gC2, gD2, gE2 Nucleoside-Modified mRNA-LNP Vaccine Provides Outstanding Protection in Mice against Genital and Non-Genital HSV-1 Infection, Comparable to the Same Antigens Derived from HSV-1.
Autor: Egan KP; Infectious Disease Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Awasthi S; Infectious Disease Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Tebaldi G; Infectious Disease Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Hook LM; Infectious Disease Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Naughton AM; Infectious Disease Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Fowler BT; Infectious Disease Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Beattie M; Acuitas Therapeutics Inc., Vancouver, BC V6T 1Z3, Canada., Alameh MG; Infectious Disease Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Weissman D; Infectious Disease Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Cohen GH; Department of Basic and Translational Sciences, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Friedman HM; Infectious Disease Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Publikováno v: Viruses [Viruses] 2023 Jun 30; Vol. 15 (7). Date of Electronic Publication: 2023 Jun 30.
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2
Akademický článek
Novel Adjuvant S-540956 Targets Lymph Nodes and Reduces Genital Recurrences and Vaginal Shedding of HSV-2 DNA When Administered with HSV-2 Glycoprotein D as a Therapeutic Vaccine in Guinea Pigs.
Autor: Awasthi S; Infectious Disease Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104-6073, USA., Onishi M; Pharmaceutical Research Division, Shionogi & Co., Ltd., Osaka 561-0825, Japan., Lubinski JM; Infectious Disease Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104-6073, USA., Fowler BT; Infectious Disease Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104-6073, USA., Naughton AM; Infectious Disease Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104-6073, USA., Hook LM; Infectious Disease Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104-6073, USA., Egan KP; Infectious Disease Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104-6073, USA., Hagiwara M; Pharmaceutical Research Division, Shionogi & Co., Ltd., Osaka 561-0825, Japan., Shirai S; Pharmaceutical Research Division, Shionogi & Co., Ltd., Osaka 561-0825, Japan., Sakai A; Pharmaceutical Research Division, Shionogi & Co., Ltd., Osaka 561-0825, Japan., Nakagawa T; Pharmaceutical Research Division, Shionogi & Co., Ltd., Osaka 561-0825, Japan., Goto K; Pharmaceutical Research Division, Shionogi & Co., Ltd., Osaka 561-0825, Japan., Yoshida O; Pharmaceutical Research Division, Shionogi & Co., Ltd., Osaka 561-0825, Japan., Stephens AJ; Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104-6073, USA., Choi G; Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104-6073, USA., Cohen GH; Department of Basic and Translational Sciences, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104-6073, USA., Katayama K; Pharmaceutical Research Division, Shionogi & Co., Ltd., Osaka 561-0825, Japan., Friedman HM; Infectious Disease Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104-6073, USA.
Publikováno v: Viruses [Viruses] 2023 May 10; Vol. 15 (5). Date of Electronic Publication: 2023 May 10.
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3
Akademický článek
Techniques for Characterizing Cytomegalovirus-Encoded miRNAs.
Autor: Diggins NL; Vaccine and Gene Therapy Institute, Oregon Health and Sciences University, Beaverton, OR, USA., Crawford LB; Vaccine and Gene Therapy Institute, Oregon Health and Sciences University, Beaverton, OR, USA., Struthers HM; Vaccine and Gene Therapy Institute, Oregon Health and Sciences University, Beaverton, OR, USA., Hook LM; Vaccine and Gene Therapy Institute, Oregon Health and Sciences University, Beaverton, OR, USA., Landais I; Vaccine and Gene Therapy Institute, Oregon Health and Sciences University, Beaverton, OR, USA., Skalsky RL; Vaccine and Gene Therapy Institute, Oregon Health and Sciences University, Beaverton, OR, USA., Hancock MH; Vaccine and Gene Therapy Institute, Oregon Health and Sciences University, Beaverton, OR, USA. hancocme@ohsu.edu.
Publikováno v: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2021; Vol. 2244, pp. 301-342.
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4
Akademický článek
Antibodies to Crucial Epitopes on HSV-2 Glycoprotein D as a Guide to Dosing an mRNA Genital Herpes Vaccine.
Autor: Hook LM; Infectious Disease Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Awasthi S; Infectious Disease Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Cairns TM; Department of Basic and Translational Sciences, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Alameh MG; Infectious Disease Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Fowler BT; Infectious Disease Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Egan KP; Infectious Disease Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Sung MMH; Acuitas Therapeutics Inc., Vancouver, BC V6T 1Z3, Canada., Weissman D; Infectious Disease Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Cohen GH; Department of Basic and Translational Sciences, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Friedman HM; Infectious Disease Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Publikováno v: Viruses [Viruses] 2022 Mar 05; Vol. 14 (3). Date of Electronic Publication: 2022 Mar 05.
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5
Akademický článek
Trivalent nucleoside-modified mRNA vaccine yields durable memory B cell protection against genital herpes in preclinical models.
Autor: Awasthi S; Infectious Disease Division, Department of Medicine and., Knox JJ; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Desmond A; Infectious Disease Division, Department of Medicine and.; Infectious Disease Division, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., Alameh MG; Infectious Disease Division, Department of Medicine and., Gaudette BT; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Lubinski JM; Infectious Disease Division, Department of Medicine and., Naughton A; Infectious Disease Division, Department of Medicine and., Hook LM; Infectious Disease Division, Department of Medicine and., Egan KP; Infectious Disease Division, Department of Medicine and., Tam YK; Acuitas Therapeutics Inc., Vancouver, British Columbia, Canada., Pardi N; Infectious Disease Division, Department of Medicine and., Allman D; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Luning Prak ET; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Cancro MP; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Weissman D; Infectious Disease Division, Department of Medicine and., Cohen GH; Department of Basic and Translational Sciences, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Friedman HM; Infectious Disease Division, Department of Medicine and.
Publikováno v: The Journal of clinical investigation [J Clin Invest] 2021 Dec 01; Vol. 131 (23).
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6
Akademický článek
Guinea Pig and Mouse Models for Genital Herpes Infection.
Autor: Hook LM; Infectious Disease Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Friedman HM; Infectious Disease Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Awasthi S; Infectious Disease Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Publikováno v: Current protocols [Curr Protoc] 2021 Dec; Vol. 1 (12), pp. e332.
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7
Akademický článek
Immunogenicity and protective efficacy of a recombinant lactococcus lactis vaccine against HSV-1 infection.
Autor: Qian, Shaoju1,2,3 (AUTHOR), Li, Ruixue4 (AUTHOR), He, Yeqing1 (AUTHOR), Wang, Hexi1 (AUTHOR), Zhang, Danqiong1 (AUTHOR), Sun, Aiping1,2 (AUTHOR), Yu, Lili1,2,3 (AUTHOR), Song, Xiangfeng1,2,3 (AUTHOR), Zhao, Tiesuo1,2,3 (AUTHOR), Chen, Zhiguo1,2,3 (AUTHOR), Yang, Zishan1,2,3 (AUTHOR) yangzishan@xxmu.edu.cn
Publikováno v: Microbial Cell Factories. 9/9/2024, Vol. 23 Issue 1, p1-14. 14p.
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8
Akademický článek
A nonhuman primate model for genital herpes simplex virus 2 infection that results in vaginal vesicular lesions, virus shedding, and seroconversion.
Autor: Wang, Kening1 (AUTHOR) kwang@niaid.nih.gov, Jordan, Tristan1 (AUTHOR), Dowdell, Kennichi1 (AUTHOR), Herbert, Richard2 (AUTHOR), Moore, Ian N.3 (AUTHOR), Koelle, David M.4,5,6,7,8 (AUTHOR), Cohen, Jeffrey I.1 (AUTHOR) kwang@niaid.nih.gov
Publikováno v: PLoS Pathogens. 9/3/2024, Vol. 20 Issue 9, p1-25. 25p.
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9
Akademický článek
Herpes simplex virus type 2 trivalent protein vaccine containing glycoproteins C, D and E protects guinea pigs against HSV-1 genital infection.
Autor: Egan K; Infectious Disease Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA, USA., Hook LM; Infectious Disease Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA, USA., Naughton A; Infectious Disease Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA, USA., Friedman HM; Infectious Disease Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA, USA., Awasthi S; Infectious Disease Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA, USA.
Publikováno v: Human vaccines & immunotherapeutics [Hum Vaccin Immunother] 2020 Sep 01; Vol. 16 (9), pp. 2109-2113. Date of Electronic Publication: 2020 Apr 29.
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10
Akademický článek
An HSV-2 nucleoside-modified mRNA genital herpes vaccine containing glycoproteins gC, gD, and gE protects mice against HSV-1 genital lesions and latent infection.
Autor: Egan KP; Infectious Disease Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Hook LM; Infectious Disease Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Naughton A; Infectious Disease Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Pardi N; Infectious Disease Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Awasthi S; Infectious Disease Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Cohen GH; Department of Basic and Translational Sciences, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Weissman D; Infectious Disease Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Friedman HM; Infectious Disease Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
Publikováno v: PLoS pathogens [PLoS Pathog] 2020 Jul 27; Vol. 16 (7), pp. e1008795. Date of Electronic Publication: 2020 Jul 27 (Print Publication: 2020).
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