Prenatal treatment for serious neurological sequelae of congenital toxoplasmosis: an observational prospective cohort study.

Autor: Mario Cortina-Borja, Hooi Kuan Tan, Martine Wallon, Malgorzata Paul, Andrea Prusa, Wilma Buffolano, Gunilla Malm, Alison Salt, Katherine Freeman, Eskild Petersen, Ruth E Gilbert, European Multicentre Study on Congenital Toxoplasmosis (EMSCOT)

Publikováno v: PLoS Medicine, Vol 7, Iss 10 (2010)

BACKGROUND:The effectiveness of prenatal treatment to prevent serious neurological sequelae (SNSD) of congenital toxoplasmosis is not known. METHODS AND FINDINGS:Congenital toxoplasmosis was prospectively identified by universal prenatal or neonatal

Externí odkaz: https://doaj.org/article/dcbd8c2e359249bfa0f53766514da268

Genetic and epigenetic factors at COL2A1 and ABCA4 influence clinical outcome in congenital toxoplasmosis.

Autor: Sarra E Jamieson, Lee-Anne de Roubaix, Mario Cortina-Borja, Hooi Kuan Tan, Ernest J Mui, Heather J Cordell, Michael J Kirisits, E Nancy Miller, Christopher S Peacock, Aubrey C Hargrave, Jessica J Coyne, Kenneth Boyer, Marie-Hélène Bessieres, Wilma Buffolano, Nicole Ferret, Jacqueline Franck, François Kieffer, Paul Meier, Dorota E Nowakowska, Malgorzata Paul, François Peyron, Babill Stray-Pedersen, Andrea-Romana Prusa, Philippe Thulliez, Martine Wallon, Eskild Petersen, Rima McLeod, Ruth E Gilbert, Jenefer M Blackwell

Publikováno v: PLoS ONE, Vol 3, Iss 6, p e2285 (2008)

Primary Toxoplasma gondii infection during pregnancy can be transmitted to the fetus. At birth, infected infants may have intracranial calcification, hydrocephalus, and retinochoroiditis, and new ocular lesions can occur at any age after birth. Not a

Externí odkaz: https://doaj.org/article/56af2f999596451881ac80907f801640

Screening for congenital toxoplasmosis: accuracy of immunoglobulin M and immunoglobulin A tests after birth

Autor: Eskild Petersen, Hooi Kuan Tan, Martine Wallon, Ruth Gilbert, Margaret Paul, Lukman Thalib

Publikováno v: Gilbert, R E, Thalib, L, Tan, H K, Paul, M, Wallon, M, Petersen, E & European Multicentre Study on Congenital Toxoplasmosis 2007, ' Screening for congenital toxoplasmosis: accuracy of immunoglobulin M and immunoglobulin A tests after birth. ', Journal of Medical Screening, vol. 14, no. 1, pp. 8-13 . https://doi.org/10.1258/096914107780154440

Objectives: To determine the accuracy of postnatal screening for toxoplasma-specific immunoglobulin (Ig) M and IgA. Setting: Ten centres in three European countries. Methods: We compared results of the first postnatal IgM or IgA test in infants with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a60225e69a5fe27892620ed644ef1600
https://doi.org/10.1258/096914107780154440

Genetic and epigenetic factors at COL2A1 and ABCA4 influence clinical outcome in congenital toxoplasmosis

Autor: Ruth Gilbert, Aubrey Hargrave, Christopher S. Peacock, Rima McLeod, Jenefer M. Blackwell, Ernest Mui, E. Nancy Miller, Michael J. Kirisits, Hooi Kuan Tan, Marie-Hélène Bessières, Lee-Anne de Roubaix, Paul Meier, Jacqueline Franck, Heather J. Cordell, Dorota Nowakowska, Eskild Petersen, Sarra E. Jamieson, François Peyron, Andrea-Romana Prusa, Philippe Thulliez, Kenneth M. Boyer, Jessica J. Coyne, Mario Cortina-Borja, Babill Stray-Pedersen, François Kieffer, Martine Wallon, Nicole Ferret, Wilma Buffolano, Małgorzata Paul

Publikováno v: PLoS ONE, Vol 3, Iss 6, p e2285 (2008)
Jamieson, S E, de Roubaix, L-A, Cortina-Borja, M, Tan, H K, Mui, E J, Cordell, H J, Kirisits, M J, Miller, E N, Peacock, C S, Hargrave, A C, Coyne, J J, Boyer, K, Bessieres, M-H, Buffolano, W, Ferret, N, Franck, J, Kieffer, F, Meier, P, Nowakowska, D E, Paul, M, Peyron, F, Stray-Pedersen, B, Prusa, A-R, Thulliez, P, Wallon, M, Petersen, E, McLeod, R, Gilbert, R E & Blackwell, J M 2008, ' Genetic and epigenetic factors at COL2A1 and ABCA4 influence clinical outcome in congenital toxoplasmosis. ', P L o S One, vol. 3, no. 6, pp. e2285 . https://doi.org/10.1371/journal.pone.0002285
PLoS ONE

Udgivelsesdato: 2008-null BACKGROUND: Primary Toxoplasma gondii infection during pregnancy can be transmitted to the fetus. At birth, infected infants may have intracranial calcification, hydrocephalus, and retinochoroiditis, and new ocular lesions c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::100ce541b1b6d4e762032ccf7d3d624e
http://europepmc.org/articles/PMC2390765?pdf=render

Supplementation with antioxidants and folinic acid for children with Down's syndrome: randomised controlled trial

Autor: Alison Salt, Rachel Pumphrey, Hooi Kuan Tan, William Henley, David P R Muller, Stuart Logan, Vanessa Edwards, Ruth Gilbert, Heather Green, Robert Moy, Sarah Davies, Cornelius Ani, Jill M Ellis

Publikováno v: BMJ (Clinical research ed.). 336(7644)

Objectives To assess whether supplementation with antioxidants, folinic acid, or both improves the psychomotor and language development of children with Down’s syndrome. Design Randomised controlled trial with two by two factorial design. Setting C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::507ca1d358814591fb696ecf5809c3f3
https://pubmed.ncbi.nlm.nih.gov/18718269