Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Hooi Hooi Ng"'
Autor:
Chen Huei Leo, Jamie Li Min Ou, Eng Shi Ong, Cheng Xue Qin, Rebecca H. Ritchie, Laura J. Parry, Hooi Hooi Ng
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 162, Iss , Pp 114578- (2023)
Background: The peptide hormone relaxin has potent anti-fibrotic and anti-inflammatory properties in various organs, including the kidneys. However, the protective effects of relaxin in the context of diabetic kidney complications remain controversia
Externí odkaz:
https://doaj.org/article/f20db91d68974d309d3eb873b03c8659
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2023)
Externí odkaz:
https://doaj.org/article/0669b52ee8fe49c3a2c761c44cae3cf7
Autor:
Valentina Dargam, Hooi Hooi Ng, Sana Nasim, Daniel Chaparro, Camila Iansen Irion, Suhas Rathna Seshadri, Armando Barreto, Zachary C. Danziger, Lina A. Shehadeh, Joshua D. Hutcheson
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundCalcific aortic valve disease (CAVD) is often undiagnosed in asymptomatic patients, especially in underserved populations. Although artificial intelligence has improved murmur detection in auscultation exams, murmur manifestation depends on
Externí odkaz:
https://doaj.org/article/b3a8ac504ace4d16acb35e1c707cd4d2
Autor:
Hooi Hooi Ng, Mariluz Soula, Bryan Rivas, Kenneth J. Wilson, Juan J. Marugan, Alexander I. Agoulnik
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Diseases, such as diabetes and hypertension, often lead to chronic kidney failure. The peptide hormone relaxin has been shown to have therapeutic effects in various organs. In the present study, we tested the hypothesis that ML290, a small molecule a
Externí odkaz:
https://doaj.org/article/586332c3834942cb94cf7cf198c3c572
Autor:
Amirala Bakhshian Nik, Hooi Hooi Ng, Manuel Garcia Russo, Francesco Iacoviello, Paul R. Shearing, Sergio Bertazzo, Joshua D. Hutcheson
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 9, Iss 6, p 168 (2022)
Atherosclerotic plaque calcification directly contributes to the leading cause of morbidity and mortality by affecting plaque vulnerability and rupture risk. Small microcalcifications can increase plaque stress and promote rupture, whereas large calc
Externí odkaz:
https://doaj.org/article/ae70db1f105446bdb394f033bc5ff05d
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Cardiovascular complications are the major cause of mortality in patients with diabetes. This is closely associated with both macrovascular and microvascular complications of diabetes, which lead to organ injuries in diabetic patients. Previous studi
Externí odkaz:
https://doaj.org/article/3735265233434841ac98e0bf770c3acd
Autor:
Amirala Bakhshian Nik, Hooi Hooi Ng, Sophie K. Ashbrook, Patrick Sun, Francesco Iacoviello, Paul R. Shearing, Sergio Bertazzo, Deniel Mero, Bohdan B. Khomtchouk, Joshua D. Hutcheson
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 324:H553-H570
Here, we investigate the potential of epidermal growth factor receptor (EGFR) inhibition to prevent vascular calcification, a leading indicator of and contributor to cardiovascular morbidity and mortality. EGFR interacts and affects the trafficking o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3fe58fa18a5a619a4de03653b7123e3f
https://doi.org/10.1152/ajpheart.00280.2022
https://doi.org/10.1152/ajpheart.00280.2022
Autor:
Amirala Bakhshian Nik, Hooi Hooi Ng, Manuel Garcia Russo, Francesco Iacoviello, Paul R. Shearing, Sergio Bertazzo, Joshua D. Hutcheson
Atherosclerotic plaque calcification directly contributes to the leading cause of morbidity and mortality by affecting the plaque vulnerability and rupture risk. Small microcalcifications can increase plaque stress and promote rupture, whereas large
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79fde19999597e9b9043e72fd60a68ef
https://doi.org/10.1101/2022.02.14.479950
https://doi.org/10.1101/2022.02.14.479950
Autor:
Amirala Bakhshian Nik, Bohdan B. Khomtchouk, Patrick Sun, Hooi Hooi Ng, Francesco Iacoviello, Paul R. Shearing, Sergio Bertazzo, Deniel Mero, Joshua D. Hutcheson
BackgroundChronic kidney disease (CKD) increases the risk of cardiovascular disease, including vascular calcification, leading to higher mortality. Release of calcifying extracellular vesicles (EVs) by vascular smooth muscle cells (VSMCs) promotes th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::849c80861aa0f43c7279acb840a48e24
https://doi.org/10.1101/2021.11.08.467799
https://doi.org/10.1101/2021.11.08.467799
Publikováno v:
Current Opinion in Pharmacology. 45:42-48
Cardiovascular disease is the most common cause of mortality worldwide, accounting for almost 50% of all deaths globally. Vascular endothelial dysfunction and fibrosis are critical in the pathophysiology of cardiovascular disease. Relaxin, an insulin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7203b6a94a2e17f42a7af5aedf46e045
https://doi.org/10.1016/j.coph.2019.04.001
https://doi.org/10.1016/j.coph.2019.04.001