Zobrazeno 1 - 10
of 398
pro vyhledávání: '"Hoogsteen base pair"'
Publikováno v:
The Journal of Physical Chemistry Letters. 12:10255-10261
The incorporation of unnatural bases in DNA programming can break through the limits of Watson-Crick and Hoogsteen base pairing to expand the diversity of DNA structures. Thus, understanding the interaction between DNA and unnatural bases is of great
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfabfda4fab8d5c8152ff8277c867907
https://doi.org/10.1021/acs.jpclett.1c02901
https://doi.org/10.1021/acs.jpclett.1c02901
Publikováno v:
Essays in Biochemistry. 65:731-740
The genomes of complex eukaryotes largely contain non-protein-coding DNA, which is pervasively transcribed into a plethora of non-coding RNAs (ncRNAs). The functional importance of many of these ncRNAs has been investigated in the last two decades, r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09f91796401313fdab9f4af7ae14c951
https://doi.org/10.1042/ebc20200089
https://doi.org/10.1042/ebc20200089
Publikováno v:
JBIC Journal of Biological Inorganic Chemistry. 25:1085-1095
To determine the factors affecting the stabilization of RNA triple-stranded structure by chiral Ru(II) polypyridyl complexes, a new pair of enantiomers, ∆-[Ru(bpy)2(7-CH3-dppz)]2+ (∆-1; bpy = 2,2′-bipyridine, 7-CH3-dppz = 7-methyl-dipyrido[3,2-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e0d6952946edf650156c010f3dbeedf
https://doi.org/10.1007/s00775-020-01825-9
https://doi.org/10.1007/s00775-020-01825-9
Publikováno v:
ACS Omega, Vol 5, Iss 24, Pp 14513-14522 (2020)
ACS Omega
ACS Omega
G-quadruplex (G4) is a noncanonical DNA secondary structure formed by Hoogsteen base pairing. It is recognized by various DNA helicases involved in DNA metabolism processes such as replication and transcription. Human Bloom syndrome protein (BLM), on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17b55a143d0a45f5e83759b17fd10fc3
https://doi.org/10.1021/acsomega.0c01176
https://doi.org/10.1021/acsomega.0c01176
Hoogsteen (HG) base-pairing is characterized by a 180° rotation of the purine base with respect to the Watson-Crick-Franklin (WCF) motif. Recently, it has been found that both conformations coexist in a dynamical equilibrium and that several biologi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15ec0d1cc0942426b4e486d02d4559ee
https://doi.org/10.1101/2021.08.04.454872
https://doi.org/10.1101/2021.08.04.454872
Autor:
Hashim M. Al-Hashimi, Maria A. Schumacher, Allison L. Stelling, Amy Y. Liu, Wenjie Zeng, Raul E. Salinas
Publikováno v:
Angewandte Chemie International Edition. 58:12010-12013
Hoogsteen DNA base pairs (bps) are an alternative base pairing to canonical Watson-Crick bps and are thought to play important biochemical roles. Hoogsteen bps have been reported in a handful of X-ray structures of protein-DNA complexes. However, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::866360c72c6761208a3b7ed1aa9e400f
https://doi.org/10.1002/anie.201902693
https://doi.org/10.1002/anie.201902693
Autor:
Yi Xue, Huiqing Zhou, Phoebe A. Rice, Bharathwaj Sathyamoorthy, Ying Z. Pigli, Hashim M. Al-Hashimi, David A. Case, Allison L. Stelling, Yu Xu
Publikováno v:
Biochemistry. 58:1963-1974
A(syn)-T and G(syn)-C+ Hoogsteen base pairs in protein-bound DNA duplexes can be difficult to resolve by X-ray crystallography due to ambiguous electron density and by nuclear magnetic resonance (NMR) spectroscopy due to poor chemical shift dispersio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d10fc5cc1a426a93c77c18ece5ddbd1e
https://doi.org/10.1021/acs.biochem.9b00027
https://doi.org/10.1021/acs.biochem.9b00027
Publikováno v:
Genes & Development. 33:282-287
Here we show that translesion synthesis (TLS) opposite 1,N6-ethenodeoxyadenosine (εdA), which disrupts Watson–Crick base pairing, occurs via Polι/Polζ-, Rev1-, and Polθ-dependent pathways. The requirement of Polι/Polζ is consistent with the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58f18da7bef206ef817363152c1a38ee
https://doi.org/10.1101/gad.320531.118
https://doi.org/10.1101/gad.320531.118
Publikováno v:
Langmuir
Funding Information: Financial support from EPSRC DTP (grant EP/R513349/1), the Emil Aaltonen Foundation, the Sigrid Jusélius Foundation, the Jane and Aatos Erkko Foundation, and the Vilho, Yrjö and Kalle Väisälä Foundation of the Finnish Academ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e52e1322d2792669b48260feb344676
https://aaltodoc.aalto.fi/handle/123456789/109038
https://aaltodoc.aalto.fi/handle/123456789/109038
Publikováno v:
The Journal of Biological Chemistry
In a previous study we showed that replication through the N1-methyl-deoxyadenosine (1-MeA) adduct in human cells is mediated via three different Polι/Polθ, Polη, and Polζ dependent pathways. Based on biochemical studies with these Pols, in the P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaa872f0f18030e6e2b4323096ff782d
https://pubmed.ncbi.nlm.nih.gov/34119520
https://pubmed.ncbi.nlm.nih.gov/34119520