Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Hoogestraat, Paul J."'
Autor:
David L. McKinzie, Bin Liu, Christian C. Felder, G. Stuart Gregory, Marla L. Watt, Robert E. Stratford, Carrie H. Croy, Hoogestraat Paul J, Jennifer R. Allen, James Andrew Jamison, Zhigang Rao, David A. Evans, William W. Turner, Frank P. Bymaster, Stephen Hitchcock, Mark G. Bures, Marvin M. Hansen, Fese M. Okha-Mokube
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 25:4158-4163
The observation that cholinergic deafferentation of circuits projecting from forebrain basal nuclei to frontal and hippocampal circuits occurs in Alzheimer's disease has led to drug-targeting of muscarinic M1 receptors to alleviate cognitive symptoms
Autor:
Liu, Bin, Croy, Carrie H., Hitchcock, Stephen A., Allen, Jennifer R., Rao, Zhigang, Evans, David, Bures, Mark G., McKinzie, David L., Watt, Marla Leigh, Stuart Gregory, G., Hansen, Marvin M., Hoogestraat, Paul J., Jamison, James A., Okha-Mokube, Fese M., Stratford, Robert E., Turner, William, Bymaster, Frank, Felder, Christian C.
Publikováno v:
In Bioorganic & Medicinal Chemistry Letters 1 October 2015 25(19):4158-4163
Publikováno v:
Tetrahedron Letters. 54:6005-6007
Intramolecular click chemistry was utilized to effect synthesis of the benzofused, triazole ring systems. The trimethylsilyl group was found to impede the reaction progress, and therefore, conditions employing in situ removal of the TMS group coupled
Publikováno v:
ChemInform. 45
Intramolecular click chemistry was utilized to effect synthesis of the benzofused, triazole ring systems. The trimethylsilyl group was found to impede the reaction progress, and therefore, conditions employing in situ removal of the TMS group coupled