Hemolysis in the spleen drives erythrocyte turnover

Autor: Klei, T.R.L ^{1, 1, 2}, Dalimot, J. ¹, Nota, B. ³, Veldthuis, M. ⁴, Mul, F.P.J ³, Rademakers, T. ⁵, Hoogenboezem, M. ³, Nagelkerke, S.Q. ¹, van IJcken, W.F.J ⁶, Oole, E. ⁶, Svendsen, P. ⁷, Moestrup, S.K. ^{7, 8}, van Alphen, F.P.J ³, Meijer, A.B. ^{3, 9, 10}, Kuijpers, T.W. ^{11, 12, 13}, van Zwieten, R. ^{1, 4}, van Bruggen, R. ¹

Publikováno v: In Blood 1 October 2020 136(14):1579-1589

Lack of eosinophil extracellular trap formation due to failure of plasma membrane breakdown in the absence of elastase.

Autor: Sprenkeler EGG; Department of Molecular Hematology, Sanquin Research and Laboratory Services and Landsteiner Laboratory, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, The Netherlands.; Department of Pediatric Immunology, Rheumatology and Infectious Diseases, Emma Children's Hospital, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, The Netherlands., Goetschalckx I; Department of Molecular Hematology, Sanquin Research and Laboratory Services and Landsteiner Laboratory, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, The Netherlands.; Department of Pediatric Immunology, Rheumatology and Infectious Diseases, Emma Children's Hospital, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, The Netherlands., Fernández Hermira S; Department of Molecular Hematology, Sanquin Research and Laboratory Services and Landsteiner Laboratory, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, The Netherlands., Tool ATJ; Department of Molecular Hematology, Sanquin Research and Laboratory Services and Landsteiner Laboratory, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, The Netherlands., Hoogenboezem M; Department of Research Facilities, Sanquin Research and Laboratory Services and Landsteiner Laboratory, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, The Netherlands., van Bruggen R; Department of Molecular Hematology, Sanquin Research and Laboratory Services and Landsteiner Laboratory, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, The Netherlands., Kuijpers TW; Department of Molecular Hematology, Sanquin Research and Laboratory Services and Landsteiner Laboratory, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, The Netherlands.; Department of Pediatric Immunology, Rheumatology and Infectious Diseases, Emma Children's Hospital, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

Publikováno v: Blood advances [Blood Adv] 2023 Oct 10; Vol. 7 (19), pp. 5868-5876.

Efficient complement-mediated clearance of immunosuppressed T cells by macrophages.

Autor: Gankema AAF; Department of Molecular Hematology, Sanquin Research, Amsterdam University Medical Center (AUMC), University of Amsterdam, Amsterdam, Netherlands., Furumaya C; Department of Molecular Hematology, Sanquin Research, Amsterdam University Medical Center (AUMC), University of Amsterdam, Amsterdam, Netherlands., Fernández-Hermira S; Department of Molecular Hematology, Sanquin Research, Amsterdam University Medical Center (AUMC), University of Amsterdam, Amsterdam, Netherlands., Hoogenboezem M; Department of Research Facilities, Sanquin Research, Amsterdam, Netherlands., Matlung HL; Department of Molecular Hematology, Sanquin Research, Amsterdam University Medical Center (AUMC), University of Amsterdam, Amsterdam, Netherlands., van Bruggen R; Department of Molecular Hematology, Sanquin Research, Amsterdam University Medical Center (AUMC), University of Amsterdam, Amsterdam, Netherlands., Kuijpers TW; Department of Molecular Hematology, Sanquin Research, Amsterdam University Medical Center (AUMC), University of Amsterdam, Amsterdam, Netherlands.; Department of Pediatric Immunology, Rheumatology and Infectious Diseases, Emma Children's Hospital, Amsterdam University Medical Center (AUMC), University of Amsterdam, Amsterdam, Netherlands.

Publikováno v: Frontiers in immunology [Front Immunol] 2023 May 16; Vol. 14, pp. 1183180. Date of Electronic Publication: 2023 May 16 (Print Publication: 2023).

Labeling and tracking of immune cells in ex vivo human skin.

Autor: Dijkgraaf FE; Division of Molecular Oncology and Immunology, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Toebes M; Division of Molecular Oncology and Immunology, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Hoogenboezem M; Research Facility, Sanquin Amsterdam, Amsterdam, the Netherlands., Mertz M; BioImaging Facility, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Vredevoogd DW; Division of Molecular Oncology and Immunology, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, the Netherlands., Matos TR; Department of Dermatology and Netherlands Institute for Pigment Disorders, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands., Teunissen MBM; Department of Dermatology and Netherlands Institute for Pigment Disorders, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands., Luiten RM; Department of Dermatology and Netherlands Institute for Pigment Disorders, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands., Schumacher TN; Division of Molecular Oncology and Immunology, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, the Netherlands. t.schumacher@nki.nl.

Publikováno v: Nature protocols [Nat Protoc] 2021 Feb; Vol. 16 (2), pp. 791-811. Date of Electronic Publication: 2020 Dec 21.

SIRPα on Mouse B1 Cells Restricts Lymphoid Tissue Migration and Natural Antibody Production.

Autor: Franke K; Sanquin Research and Landsteiner Laboratory, Department of Blood Cell Research, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands., Pillai SY; Department of Pulmonary Medicine, Erasmus MC, Rotterdam, Netherlands., Hoogenboezem M; Sanquin Research and Landsteiner Laboratory, Department of Plasma Protein, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands., Gijbels MJJ; Department of Medical Biochemistry, Experimental Vascular Biology, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.; Department of Pathology, CARIM, Cardiovascular Research Institute Maastricht, GROW-School for Oncology and Developmental Biology, Maastricht University, Maastricht, Netherlands., Matlung HL; Sanquin Research and Landsteiner Laboratory, Department of Blood Cell Research, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands., Geissler J; Sanquin Research and Landsteiner Laboratory, Department of Blood Cell Research, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands., Olsman H; Sanquin Research and Landsteiner Laboratory, Department of Blood Cell Research, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands., Pottgens C; Department of Medical Biochemistry, Experimental Vascular Biology, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands., van Gorp PJ; Department of Medical Biochemistry, Experimental Vascular Biology, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands., Ozsvar-Kozma M; Department of Laboratory Diagnostics, Medical University of Vienna, Vienna, Austria., Saito Y; Division of Molecular and Cellular Signaling, Department of Biochemistry and Molecular Biology, Kobe University Graduate School of Medicine, Kobe, Japan., Matozaki T; Division of Molecular and Cellular Signaling, Department of Biochemistry and Molecular Biology, Kobe University Graduate School of Medicine, Kobe, Japan., Kuijpers TW; Sanquin Research and Landsteiner Laboratory, Department of Blood Cell Research, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.; Department of Pediatric Hematology, Immunology and Infectious Disease, Emma Children's Hospital, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands., Hendriks RW; Department of Pulmonary Medicine, Erasmus MC, Rotterdam, Netherlands., Kraal G; Department of Molecular Cell Biology and Immunology, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Infection and Immunity Institute, Amsterdam, Netherlands., Binder CJ; Department of Laboratory Diagnostics, Medical University of Vienna, Vienna, Austria., de Winther MPJ; Department of Medical Biochemistry, Experimental Vascular Biology, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.; Institute for Cardiovascular Prevention (IPEK), Munich, Germany., van den Berg TK; Sanquin Research and Landsteiner Laboratory, Department of Blood Cell Research, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.; Department of Molecular Cell Biology and Immunology, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Infection and Immunity Institute, Amsterdam, Netherlands.

Publikováno v: Frontiers in immunology [Front Immunol] 2020 Oct 09; Vol. 11, pp. 570963. Date of Electronic Publication: 2020 Oct 09 (Print Publication: 2020).