A photoactivable natural product with broad antiviral activity against enveloped viruses including highly pathogenic coronaviruses

Autor: Meunier, Thomas, Desmarets, Lowiese, Bordage, Simon, Bamba, Moussa, Hervouet, Kévin, Rouillé, Yves, François, Nathan, Decossas, Marion, Sencio, Valentin, Trottein, François, Honora Tra Bi, Fézan, Lambert, Olivier, Dubuisson, Jean, Belouzard, Sandrine, Sahpaz, Sevser, Séron, Karin

Publikováno v: Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, In press, ⟨10.1128/AAC.01581-21⟩
Antimicrobial Agents and Chemotherapy, 2022, ⟨10.1128/AAC.01581-21⟩

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak has highlighted the need for broad-spectrum antivirals against coronaviruses (CoVs). Here, pheophorbide a (Pba) was identified as a highly active antiviral molecule against hum

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::7faf48b931971ee0302125f7a0d81873
https://hal.archives-ouvertes.fr/hal-03447751/file/AAC01581-21R1_Merged_PDF.pdf