Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Honoré Monti"'
Publikováno v:
Synthesis. 2009:290-296
Starting from ethyl (1 S,4 R)-4-hydroxy-2-methylcyclopent-2-ene-1-carboxylate,as a common enantiopure building block readily obtained by enzymatickinetic resolution of the corresponding racemic derivative, 3′-methylcarbovir,3′-methylabacavir, and
Publikováno v:
Synthesis. 2008:3253-3260
A series of 3'-methyl-branched and purine-modified analogues of aristeromycin were synthesized via the SN 2 displacement of a key triflate, which was prepared from a readily available enantiopure building block in eight steps. The synthesized compoun
Publikováno v:
The Journal of Organic Chemistry. 73:6033-6036
Danishefsky's taxol CD ring key intermediate is synthesized in 15 steps and 11.4% overall yield from a readily available starting material. Absolute stereochemistry of the starting material and stereocontrolled steps determine the absolute configurat
Publikováno v:
European Journal of Organic Chemistry. 2007:2802-2807
The first enantioselective synthesis of two new monoterpene aldehyde-esters from Bupleurum gibraltaricum, starting from an enantiopure building block, is described. The key step is a strictly controlled esterification to afford the somewhat unstable
Publikováno v:
Tetrahedron. 63:5050-5055
Starting from a readily available enantiopure building block, a straightforward enantioselective approach to 3′-methyl-2′,3′-β-oxirane-fused carbanucleosides bearing adenosine analogues is detailed. The key steps in the syntheses involved a li
Publikováno v:
Synlett. 2006:2215-2218
This paper describes the racemic and stereoselective synthesis of novel conformationally locked 3'-methyl-2',3'-oxiranefused carbocyclic nucleosides (nucleosides numbering). The key step is the direct coupling of an alcohol bearing the 1-methyl-6-oxa
Publikováno v:
Synlett. 2006:0403-0406
A convenient chemoenzymatic enantioconvergent access to enantiomerically pure (+)- or (-)-4-hydroxy-3-methyl-2-cyclohexenone is described using a one-pot two-step kinetic resolution-stereoinversion protocol followed by hydrolysis. The key step of the
Publikováno v:
Tetrahedron. 61:9545-9549
This paper reports the straightforward enantioselective synthesis of (+)-ancistrofuran starting from a readily available enantiopure building block. A stereofacial directed diastereoselective addition of an organocerate for the installation of the re
Publikováno v:
European Journal of Organic Chemistry. 2004:5092-5099
An enantioselective synthesis of (+)-1,14-herbertenediol, and a formal enantioselective synthesis of (−)-α-herbertenol and (−)-herbertenediol, employing a lipase-promoted and a key stereoselective alkylation of a cyclopentane unit based methodol
Publikováno v:
Tetrahedron. 60:5907-5912
The first enantioselective synthesis of tochuinyl acetate and dihydrotochuinyl acetate, two natural marine products isolated from Tochuina tetraquetra and Gersemia rubiformis, has been achieved starting from an enantiopure building block. The key fea