Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Hongzhu Qu"'
Autor:
Yanxia Liu, Jie Liu, Shouwei Zhang, Jinyue Wang, Zhihong Sun, Huaibo Sun, Ying Yang, Guangmin Zheng, Yu Huang, Meng Li, Zhaojun Zhang, Jingfa Xiao, Changqing Zeng, Chengming Sun, Hongzhu Qu, Xiangdong Fang
Publikováno v:
Scientific Data, Vol 11, Iss 1, Pp 1-7 (2024)
Abstract Circulating cell-free DNA (cfDNA) in the peripheral blood is a promising biomarker for cancer diagnosis and prognosis. Somatic mutations identified in cancers have been used to detect therapeutic targets for clinical transformation and indiv
Externí odkaz:
https://doaj.org/article/581c58582de848a69c249dc9519845d6
Autor:
Weilong Zou, Zhanjie Fang, Yu Feng, Shangjin Gong, Ziqiang Li, Meng Li, Yong Sun, Xiuyan Ruan, Xiangdong Fang, Hongzhu Qu, Haiyang Li
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Patients with primary multifocal hepatocellular carcinoma (HCC) have a poor prognosis and often experience a high rate of treatment failure. Multifocal HCC is mainly caused by intrahepatic metastasis (IM), and though portal vein t
Externí odkaz:
https://doaj.org/article/2ab88a413e504fe3ad1f9be2e847df9e
Autor:
Mingshu Sun, Wenyan Sun, Xuetong Zhao, Zhiqiang Li, Nicola Dalbeth, Aichang Ji, Yuwei He, Hongzhu Qu, Guangmin Zheng, Lidan Ma, Jiayi Wang, Yongyong Shi, Xiangdong Fang, Haibing Chen, Tony R. Merriman, Changgui Li
Publikováno v:
Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-9 (2022)
Abstract Objectives The objective of this study was to develop and validate a prediction model for renal urate underexcretion (RUE) in male gout patients. Methods Men with gout enrolled from multicenter cohorts in China were analyzed as the developme
Externí odkaz:
https://doaj.org/article/9fd65e7718da4c6186287e8416586427
Autor:
Yaqiang Hong, Dake Zhang, Xiangtian Zhou, Aili Chen, Amir Abliz, Jian Bai, Liang Wang, Qingtao Hu, Kenan Gong, Xiaonan Guan, Mengfei Liu, Xinchang Zheng, Shujuan Lai, Hongzhu Qu, Fuxin Zhao, Shuang Hao, Zhen Wu, Hong Cai, Shaoyan Hu, Yue Ma, Junting Zhang, Yang Ke, Qian-Fei Wang, Wei Chen, Changqing Zeng
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 20, Iss 1, Pp 177-191 (2022)
Postzygotic mutations are acquired in normal tissues throughout an individual’s lifetime and hold clues for identifying mutagenic factors. Here, we investigated postzygotic mutation spectra of healthy individuals using optimized ultra-deep exome se
Externí odkaz:
https://doaj.org/article/40f7d499a249494bb108fc3b3d79f158
Autor:
Yunlong Cui, Hongfeng Li, Pengfei Liu, Hailong Wang, Zhenzhen Zhang, Hongzhu Qu, Caijuan Tian, Xiangdong Fang
Publikováno v:
Frontiers in Genetics, Vol 13 (2023)
Background: Genetic testing is becoming more and more accepted in the auxiliary diagnosis and treatment of tumors. Due to the different performance of the existing bioinformatics software and the different analysis results, the needs of clinical diag
Externí odkaz:
https://doaj.org/article/78409ca028f74319b4777a7657225067
Autor:
Quanquan Lin, Zhanjie Fang, Jinlong Sun, Fei Chen, Yipeng Ren, Zhenhong Fu, Sefei Yang, Lin Feng, Feng Wang, Zhigang Song, Wei Chen, Wenjun Yu, Chen Wang, Yixin Shi, Yue Liang, Haizhong Zhang, Hongzhu Qu, Xiangdong Fang, Qing Xi
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Adenoid cystic carcinoma (ACC) is a malignant tumor that originates from exocrine gland epithelial cells. We profiled the transcriptomes of 49,948 cells from paracarcinoma and carcinoma tissues of three patients using single-cell RNA sequencing. Thre
Externí odkaz:
https://doaj.org/article/4ff0182e462d40269f8ff11b7c972660
Autor:
Bing Liu, Chen Wang, Zhanjie Fang, Jing Bai, Ying Qian, Yuanyuan Ma, Xiuyan Ruan, Shi Yan, Shaolei Li, Yaqi Wang, Bin Dong, Xin Yang, Meng Li, Xuefeng Xia, Hongzhu Qu, Xiangdong Fang, Nan Wu
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Pure ground glass nodules (GGNs) and solid nodules (SNs) represent early and relatively late stages of lung adenocarcinoma (LUAD) in radiology, respectively. The cellular and molecular characteristics of pure GGNs and SNs have not been comprehensivel
Externí odkaz:
https://doaj.org/article/8f4fe7c587e143f3aa65084fd4ec0c27
Autor:
Junwei Zhu, Yunxiao Ren, Yuanyuan Han, Tingting Jin, Yanming Li, Xiuyan Ruan, Hongzhu Qu, Shengwen Huang, Zhaojun Zhang, Xiangdong Fang
Publikováno v:
Blood Science, Vol 1, Iss 2, Pp 161-167 (2019)
Abstract. Erythropoiesis is a complex and sophisticated multi-stage process regulated by a variety of factors, including the transcription factor GATA1 and non-coding RNA. GATA1 is regarded as an essential transcriptional regulator promoting transcri
Externí odkaz:
https://doaj.org/article/2cf8f8bf58f044c781f85a4e49b3c6d6
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 17, Iss 4, Pp 465-471 (2019)
Gliomas are one of the most common types of brain cancers. Numerous efforts have been devoted to studying the mechanisms of glioma genesis and identifying biomarkers for diagnosis and treatment. To help further investigations, we present a comprehens
Externí odkaz:
https://doaj.org/article/efab379236c74c99ad5e5762df2423e5
Autor:
Zhenglin Du, Liang Ma, Hongzhu Qu, Wei Chen, Bing Zhang, Xi Lu, Weibo Zhai, Xin Sheng, Yongqiao Sun, Wenjie Li, Meng Lei, Qiuhui Qi, Na Yuan, Shuo Shi, Jingyao Zeng, Jinyue Wang, Yadong Yang, Qi Liu, Yaqiang Hong, Lili Dong, Zhewen Zhang, Dong Zou, Yanqing Wang, Shuhui Song, Fan Liu, Xiangdong Fang, Hua Chen, Xin Liu, Jingfa Xiao, Changqing Zeng
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 17, Iss 3, Pp 229-247 (2019)
To unravel the genetic mechanisms of disease and physiological traits, it requires comprehensive sequencing analysis of large sample size in Chinese populations. Here, we report the primary results of the Chinese Academy of Sciences Precision Medicin
Externí odkaz:
https://doaj.org/article/876307fe301c4335b2f7998fad12cc15