Zobrazeno 1 - 10
of 373
pro vyhledávání: '"Hongzhe Sun"'
Publikováno v:
Chinese Journal of Mechanical Engineering, Vol 36, Iss 1, Pp 1-19 (2023)
Abstract Legged robots use isolated footholds to support, which have the merit of good terrain trafficability but lack speed ability. In contrast, wheeled robots have the advantages of high speed and efficiency but only run on flat roads. To improve
Externí odkaz:
https://doaj.org/article/90c5c6d11da54629ab709c915c397f37
Autor:
Chenyuan Wang, Yushan Xia, Runming Wang, Jingru Li, Chun-Lung Chan, Richard Yi-Tsun Kao, Patrick H. Toy, Pak-Leung Ho, Hongyan Li, Hongzhe Sun
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract The rapid emergence of antimicrobial resistance (AMR) pathogens highlights the urgent need to approach this global burden with alternative strategies. Cefiderocol (Fetroja®) is a clinically-used sideromycin, that is utilized for the treatme
Externí odkaz:
https://doaj.org/article/c1898164917c40cdbcd6259a2256dd7e
Autor:
Yufei Mo, Ming Yue, Lok Yan Yim, Runhong Zhou, Chunhao Yu, Qiaoli Peng, Ying Zhou, Tsz-Yat Luk, Grace Chung-Yan Lui, Huarong Huang, Chun Yu Hubert Lim, Hui Wang, Li Liu, Hongzhe Sun, Jun Wang, Youqiang Song, Zhiwei Chen
Publikováno v:
EBioMedicine, Vol 98, Iss , Pp 104877- (2023)
Summary: Background: HIV-1-associated immune activation drives CD4+ T cell depletion and the development of acquired immunodeficiency syndrome. We aimed to determine the role of nicotinamide mononucleotide (NMN), the direct precursor of nicotinamide
Externí odkaz:
https://doaj.org/article/54e9a91cd4604b2a9a8e451b41efab99
Autor:
Peng Gao, Yuanxin Wei, Suying Hou, Pok-Man Lai, Han Liu, Sherlock Shing Chiu Tai, Victor Yat Man Tang, Pradeep Halebeedu Prakash, Kong-Hung Sze, Jonathan Hon Kwan Chen, Hongzhe Sun, Xuechen Li, Richard Yi-Tsun Kao
Publikováno v:
Emerging Microbes and Infections, Vol 12, Iss 2 (2023)
Staphylococcus aureus is a major human pathogen responsible for a wide range of clinical infections. SaeRS is one of the two-component systems in S. aureus that modulate multiple virulence factors. Although SaeR is required for S. aureus to develop a
Externí odkaz:
https://doaj.org/article/5307efbe8a49412ab673ba50402d56c3
Autor:
Haibo Wang, Ligang Hu, Hongyan Li, Yau-Tsz Lai, Xueying Wei, Xiaohan Xu, Zhenkun Cao, Huiming Cao, Qianya Wan, Yuen-Yan Chang, Aimin Xu, Qunfang Zhou, Guibin Jiang, Ming-Liang He, Hongzhe Sun
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Despite common use as a diabetes mellitus supplement, chromium(III)’s pharmacological effects remain unknown. We identified the Cr(III)-proteome in cells with a metalloproteomic approach and uncovered ATP synthase as a vital target to relieve hyper
Externí odkaz:
https://doaj.org/article/ebb358f635fc490abc88ac9e02242555
Publikováno v:
Case Studies in Thermal Engineering, Vol 45, Iss , Pp 102932- (2023)
To address the challenge of the growing global energy crisis and the greenhouse effect, employing the thermoradiative effect of photodiodes to harvest radiative energy from colder outer space is considered a promising approach for direct nighttime re
Externí odkaz:
https://doaj.org/article/6f687292189f44708e22e38263852482
Autor:
Regina Huang, Zhiwen Zhou, Xinmiao Lan, Fung Kit Tang, Tianfan Cheng, Hongzhe Sun, Ken Cham-Fai Leung, Xuan Li, Lijian Jin
Publikováno v:
Materials Today Bio, Vol 18, Iss , Pp 100507- (2023)
Antibiotic resistance is a global public health threat, and urgent actions should be undertaken for developing alternative antimicrobial strategies and approaches. Notably, bismuth drugs exhibit potent antimicrobial effects on various pathogens and p
Externí odkaz:
https://doaj.org/article/56e395a355c24c0a98cebcf39a5b5277
Autor:
Haibo Wang, Minji Wang, Xiaohan Xu, Peng Gao, Zeling Xu, Qi Zhang, Hongyan Li, Aixin Yan, Richard Yi-Tsun Kao, Hongzhe Sun
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Silver (Ag) has been used as an antimicrobial agent since a long time, but its molecular mechanism of action was not elucidated due to technical challenges. Here, the authors develop a mass spectrometric approach to identify the Ag-proteome in Staphy
Externí odkaz:
https://doaj.org/article/793574555794407d804bad3dd59bbdde
Autor:
Hongzhe Sun, Qi Zhang, Runming Wang, Haibo Wang, Yuen-Ting Wong, Minji Wang, Quan Hao, Aixin Yan, Richard Yi-Tsun Kao, Pak-Leung Ho, Hongyan Li
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Multi-drug resistant pathogens remain a serious public health threat. Here, Sun and colleagues identify a role for auranofin, which is normally used as a drug for rheumatoid arthritis, for reversing antibiotic resistance to carbapenem and colistin.
Externí odkaz:
https://doaj.org/article/f7e57cb418f248e6bdad5f3c045c4159
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Microbial persisters enable the development of certain intrinsic strategies for survival with extreme tolerance to multiple antimicrobials. Porphyromonas gingivalis is considered to be the “keystone” periodontopathogen. Indeed, periodontitis, as
Externí odkaz:
https://doaj.org/article/585cda467f004254b93bdd286d4743ea