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Akademický článek

Fabrication of pH-dependent solid dispersion for oral colon-targeted delivery of notoginsenoside R1 and its protective effects on ulcerative colitis mice

Autor: Hongyun Tie, Yaru Wang, Yunxia Shang, Manlin Li, Xiaohui Wei, Zhengtao Wang

Publikováno v: Heliyon, Vol 9, Iss 9, Pp e20280- (2023)

Notoginsenoside R1 (R1), which originated from the rhizomes and roots of Panax notoginseng, is classified as a Biopharmaceutical Classification System class III drug with good solubility but poor oral absorption. Although R1 can alleviate the inflamm

Externí odkaz: https://doaj.org/article/f1a94835329f49dc92f43d3911c7a8e0

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Identify Key Active Ingredients and Molecular Mechanisms of Jiangzhi Decoction on Non-alcoholic Fatty Liver Disease by Network Pharmacology Analysis

Autor: Lei Wang, Yin Zhi, Ying Ye, Miao Zhang, Xing Ma, Hongyun Tie, Wei Xia, Yanan Song

Background: Jiangzhi Decoction (JZD), a traditional herb mixture, has shown significant clinical efficacy against non-alcoholic fatty liver disease (NAFLD). However, its multicomponent and multitarget characteristics bring difficulty in deciphering i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9920df414c9e1219a4ef58086d5b3eab
https://doi.org/10.21203/rs.3.rs-35476/v1

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