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Akademický článek

Lysosomal Ca2+ release-facilitated TFEB nuclear translocation alleviates ischemic brain injury by attenuating autophagic/lysosomal dysfunction in neurons

Autor: Qian Lei, Xuemei Chen, Yajie Xiong, Shangdan Li, Jiaqian Wang, Hongyun He, Yihao Deng

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)

Abstract Neuronal death was frequently driven by autophagic/lysosomal dysfunction after ischemic stroke, whereas how to restore the impaired autophagic flux remained elusive. Autophagic/lysosomal signaling could be augmented after transcription facto

Externí odkaz: https://doaj.org/article/ed1f662750754d7a851db6903e979242

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Akademický článek

N-ethylmaleimide-sensitive factor elicits a neuroprotection against ischemic neuronal injury by restoring autophagic/lysosomal dysfunction

Autor: Miaomiao Qiu, Xiaoming Zhao, Tao Guo, Hongyun He, Yihao Deng

Publikováno v: Cell Death Discovery, Vol 10, Iss 1, Pp 1-11 (2024)

Abstract Autophagosome-lysosome fusion defects play a critical role in driving autolysosomal dysfunction, leading to autophagic/lysosomal impairment in neurons following ischemic stroke. However, the mechanisms hindering autophagosome-lysosome fusion

Externí odkaz: https://doaj.org/article/8306f94785f6473683a4d6ff8cb56e96

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Akademický článek

Psychophysiological restorative potential in cancer patients by virtual reality (VR)-based perception of natural environment

Autor: Rui Song, Qujing Chen, Ying Zhang, Qing'an Jia, Hongyun He, Tian Gao, Ling Qiu

Publikováno v: Frontiers in Psychology, Vol 13 (2022)

The positive significance of nature to human’ self-reported well-being has been widely confirmed, but less attention has been paid to the study of cancer patients, as well as the role of time on the restorative effects. Therefore, using virtual rea

Externí odkaz: https://doaj.org/article/eec680e2944f4e9f863dc96c5a99d08d

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Akademický článek

Calculation and Analysis of Electromagnetic Characteristics of Double-Fed Linear Motor

Autor: Ying Wang, Hongyun He, Weiguo Lu, Xiaofen Geng, Yang Xu, Zongjian Li

Publikováno v: IEEE Access, Vol 7, Pp 12291-12296 (2019)

This paper presents the calculation analysis of the electromagnetic characteristics in double-fed linear motor (DFLM). First, the one-dimensional electromagnetic field model of DFLM is established. In addition, the analytical formulas of airgap magne

Externí odkaz: https://doaj.org/article/ca06b47235c843d8bd794321d4aeb94b

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Akademický článek

Breviscapine confers a neuroprotective efficacy against transient focal cerebral ischemia by attenuating neuronal and astrocytic autophagy in the penumbra

Autor: Pengyue, Zhang, Tao, Guo, Hongyun, He, Liqiang, Yang, Yihao, Deng

Publikováno v: In Biomedicine & Pharmacotherapy June 2017 90:69-76

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Akademický článek

Puerarin provides a neuroprotection against transient cerebral ischemia by attenuating autophagy at the ischemic penumbra in neurons but not in astrocytes

Autor: Hongyun, He, Tao, Guo, Pengyue, Zhang, Liqiang, Yang, Yihao, Deng

Publikováno v: In Neuroscience Letters 16 March 2017 643:45-51

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Akademický článek

EVALUATION OF LEFT VENTRICULAR FUNCTION IN HYPERTENSIVE ATHLETIC PATIENTS WITH DIFFERENT CIRCADIAN RHYTHMS USING STRATIFIED STRAIN TECHNIQUE.

Autor: Hongyun He, Guangjun Zhang, Yunzhao Hu

Publikováno v: International Journal of Medicine & Science of Physical Activity & Sport / Revista Internacional de Medicina y Ciencias de la Actividad Física y del Deporte; mar2024, Vol. 24 Issue 95, p290-304, 15p

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Akademický článek

Melibiose Confers a Neuroprotection against Cerebral Ischemia/Reperfusion Injury by Ameliorating Autophagy Flux via Facilitation of TFEB Nuclear Translocation in Neurons

Autor: Zhiyuan Wu, Yongjie Zhang, Yuyuan Liu, Xuemei Chen, Zhiwen Huang, Xiaoming Zhao, Hongyun He, Yihao Deng

Publikováno v: Life, Vol 11, Iss 9, p 948 (2021)

Autophagic/lysosomal dysfunction is a critical pathogenesis of neuronal injury after ischemic stroke. Trehalose has been validated to restore the impaired autophagy flux by boosting transcription factor EB (TFEB) nuclear translocation, but orally adm

Externí odkaz: https://doaj.org/article/44332d8c54fa48bb807fc13356109fc4

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[Activation of JNK induces apoptosis to autophagy conversion and enhances the survival of oxygen-glycogen deprived rat neurons]

Autor: Zhiwen, Huang, Lu, Ren, Yihao, Deng, Hongyun, He

Publikováno v: Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. 38(5)

Objective To investigate the efficacy and mechanism of c-Jun N-terminal kinase (JNK) in boosting survival of oxygen glucose deprivation (OGD) rat neurons. Methods The cortex neurons from fetal rats were primarily cultured to prepare a model of OGD ne

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::06176010bc2a431364e871476db84527
https://pubmed.ncbi.nlm.nih.gov/35603649

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