Zobrazeno 1 - 10
of 149
pro vyhledávání: '"Hongyu Qin"'
Autor:
Ke Lu, Ming Zhang, Hongyu Qin, Siyu Shen, Haiqing Song, Hua Jiang, Chunxiang Zhang, Guozhi Xiao, Liping Tong, Qing Jiang, Di Chen
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 7, Pp 2977-2991 (2024)
Cyclin D1 has been recognized as an oncogene due to its abnormal upregulation in different types of cancers. Here, we demonstrated that cyclin D1 is SUMOylated, and we identified Itch as a specific E3 ligase recognizing SUMOylated cyclin D1 and media
Externí odkaz:
https://doaj.org/article/cbcacfc28a4a4fb8b240e5790891f587
Autor:
Wenbin Cao, Yulin Zhang, Jia Qi, Yanru Zhang, Ruike Ding, Bin Meng, Juan Zhao, Shiwei Luo, Chong Shen, Chenjin Duan, Hongyu Qin, Yun Ye, Enqi Liu, Pengxiang Qu
Publikováno v:
Scientific Data, Vol 11, Iss 1, Pp 1-8 (2024)
Abstract Obesity is accompanied by multiple known health risks and increased morbidity, and obese men display reduced reproductive health. However, the impact of obesity on the testes at the molecular levels remain inadequately explored. This is part
Externí odkaz:
https://doaj.org/article/da6cec7ecaec4931b148f4084384c445
Autor:
Hua Jiang, Hongyu Qin, Qinghua Yang, Longao Huang, Xiao Liang, Congyang Wang, Abu Moro, Sheng Xu, Qingjun Wei
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-22 (2024)
Abstract Background The use of gene therapy to deliver microRNAs (miRNAs) has gradually translated to preclinical application for the treatment of intervertebral disc degeneration (IDD). However, the effects of miRNAs are hindered by the short half-l
Externí odkaz:
https://doaj.org/article/4523faaee55d4c07a5c39b74191dc37a
Publikováno v:
Progress in Fishery Sciences, Vol 45, Iss 2, Pp 220-232 (2024)
The insulin-like growth factor (IGF) system plays a key regulatory role in biological processes, such as growth, reproduction, early development, cell differentiation, and proliferation, in fish and other vertebrates. The IGF family system consists o
Externí odkaz:
https://doaj.org/article/19441de861b649829ac56396081b89f7
Impact of high-fat diet on ovarian epigenetics: Insights from altered intestinal butyric acid levels
Autor:
Jia Qi, Congcong Xia, Yulin Zhang, Ruike Ding, Yanru Zhang, Wenbin Cao, Chenjing Duan, Zijing Yao, Hongyu Qin, Yun Ye, Pengxiang Qu, Yandong Li, Enqi Liu
Publikováno v:
Heliyon, Vol 10, Iss 12, Pp e33170- (2024)
Objective: To investigate the effects of a high-fat diet (HFD) on the gut bacterium Roseburia intestinalis and butyric acid levels, and to assess their impact on ovarian function and epigenetic markers in mice. Methods: A total of 20 female ICR mice
Externí odkaz:
https://doaj.org/article/1ac111ead6d644308eb7624b786cd901
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 19, Iss 1, Pp 1-8 (2024)
Abstract Objective To assess whether there is a difference between measurements of odontoid incidence (OI) and other cervical sagittal parameters by X-ray radiography and those by supine magnetic resonance imaging (MRI). Methods Standing X-ray and su
Externí odkaz:
https://doaj.org/article/78243743b66e447d892068ec6bce99c8
Autor:
Xiao Liang, Xin Qi, Jin Yang, Xiaorui Wang, Hongyu Qin, Fang Hu, Han Bai, Yixin Li, Chengsheng Zhang, Bingyin Shi
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundCOVID-19 is a highly infectious respiratory disease that can manifest in various clinical presentations. Although many studies have reported the lipidomic signature of COVID-19, the molecular changes in asymptomatic severe acute respiratory
Externí odkaz:
https://doaj.org/article/aa55563347a64f19838d09ca35d17373
Autor:
Yuhang Zhou, Guoyu Li, Saifei Feng, Hongyu Qin, Qiancheng Wang, Fang Shen, Penggao Liu, Yanping Huang, Huibing He
Publikováno v:
Advanced Science, Vol 10, Iss 6, Pp n/a-n/a (2023)
Abstract The high Zn ion desolvation energy, sluggish Zn deposition kinetics, and top Zn plating pattern are the key challenges toward practical Zn anodes. Herein, these key issues are addressed by introducing zinc pyrovanadate (ZVO) as a solid zinc
Externí odkaz:
https://doaj.org/article/cbb465d2e6434944821e552709d12438
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2023)
Introduction: Development of Poly (ADP-ribose) polymerase (PARP) inhibitors has been extensively studied in cancer treatment. Olaparib, the first approved PARP inhibitor, showed potency in the inhibition of both BRCA (breast cancer associated)-mutate
Externí odkaz:
https://doaj.org/article/0f74626b446c4f60b8b6cee9c71d304f
Autor:
Jiarong Zhang, Feixia Li, Xiaoyu Zhang, Ting Xie, Hongyu Qin, Junxian Lv, Yunhong Gao, Mingyue Li, Yuntao Gao, Yudong Jia
Publikováno v:
Antioxidants, Vol 12, Iss 7, p 1389 (2023)
High-quality eggs are essential for the sustainability of commercial aquaculture production. Melatonin is a potent candidate for regulating the growth and maturation of oocytes. Therefore, research on the effect of melatonin on marine fish oocytes in
Externí odkaz:
https://doaj.org/article/815dc0cddf9d46999119dee7634ee556