Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Hongying Chao"'
Autor:
Jie Liu, WenMin Han, Xiaohui Cai, Zheng Wang, LiuJun Cao, HaiYing Hua, ZhuXia Jia, HongYing Chao, XuZhang Lu, HongJie Shen
Publikováno v:
Hematology, Vol 27, Iss 1, Pp 565-574 (2022)
Introduction The aim of the study was to determine molecular genetic and clinical characterization of acute myeloid leukemia (AML) with trisomy 8 as the sole chromosome abnormality, a recurrent but rare chromosomal abnormality in AML.Methods Interpha
Externí odkaz:
https://doaj.org/article/c00a530fdb5e4b46a9b10420fb134e27
Autor:
Ting Wang, Haiying Hua, Zheng Wang, Biao Wang, Liujun Cao, Wei Qin, Pin Wu, Xiaohui Cai, Hongying Chao, XuZhang Lu
Publikováno v:
Hematology, Vol 27, Iss 1, Pp 994-1002 (2022)
Introduction Several studies have confirmed that mutations in the Wilms tumor 1 (WT1) gene occur in adult acute myeloid leukemia (AML). However, few data are available regarding the incidence of WT1 mutations in CEBPAmut AML and their impact.Methods
Externí odkaz:
https://doaj.org/article/dc842811e7404d99974cd29b453ebbe8
Publikováno v:
Leukemia Research Reports, Vol 11, Iss , Pp 24-26 (2019)
The natural history of primary hypereosinophilia remains poorly defined, given the underlying disease heterogeneity. Recently, targeted NGS helps to establish clonality in a subset of patients with hypereosinophilia. We first reported the clonal evol
Externí odkaz:
https://doaj.org/article/908af35940b045aa89da52cf925e7e66
Publikováno v:
Chinese Medical Journal, Vol 128, Iss 1, Pp 131-132 (2015)
Externí odkaz:
https://doaj.org/article/d954666fcfb1457aa3a627b414a6c380
Autor:
Zheng Wang, Jiao Li, Weiwei Miao, Hongying Chao, Lijun Wen, Jinlan Pan, Zhao Zeng, Yi Xu, Xiaosen Bian, Jun Zhang, Wenzhong Wu, Suning Chen, Li Yao, Zhen Shen
Publikováno v:
Journal of Leukocyte Biology. 111:981-987
ETO2 is a nuclear co-repressor, which plays a critical role in the regulation of the cell cycle, self-renewal capacity, and differentiation of hematopoietic progenitor cells. We identified novel fusion transcripts involving ETO2 and CTCF by RNA-seq i
Autor:
Xiaohui Cai, Jinfei Wang, Hongying Chao, Jianfang Liu, Jingtao Lu, Zhuxia Jia, Meiyu Chen, Xuzhang Lu
Publikováno v:
Acta Haematologica. 145:144-151
Mixed lineage leukemia (MLL) T10 is a relatively rare partner for the KMT2A lysine (K)-specific methyltransferase 2A gene. The common features and coexisting mutations of acute myeloid leukemia (AML) patients with KMT2A-MLLT10 remain unknown. In this
Autor:
Wenmin Han, Xiaohui Cai, Zheng Wang, Xuzhang Lu, Wei Qin, Hongying Chao, Haiying Hua, Feng Zhou, Zhuxia Jia, Jie Liu, Meiyu Chen
Publikováno v:
International Journal of Hematology. 115:21-32
We evaluated the mutational landscape of chronic myelomonocytic leukemia (CMML) and its potential clinical significance. We analyzed 47 samples with a panel of 112 genes using next-generation sequencing. Forty-five of the 47 patients (95.74%) had at
Autor:
Zonghan Xu, Ling Zhang, Lijun Wen, Hongying Chao, Qinrong Wang, Miao Sun, Hongjie Shen, Suning Chen, Zheng Wang, Jian Lu
Publikováno v:
Ann Transl Med
BACKGROUND: Chordoma is a rare malignant bone tumor with high recurrence and metastasis rates. Little is known about the mutational process of this incurable disease. The aim of our research was to explore the potential driver genes and signal pathwa
Autor:
Pin Wu, Xuzhang Lu, Zhu Xia Jia, Xiaohui Cai, Hongjie Shen, Haiying Hua, Hongying Chao, Wenmin Han, Feng Zhou, Zheng Wang
Publikováno v:
International journal of laboratory hematologyREFERENCES. 44(2)
Background Autosomal trisomy is a relatively rare abnormality observed in AML, occurring singly or as a secondary event in association with other karyotypic changes, and associated with prognosis. The molecular genetic and clinical characterizations
Autor:
JinYuan He, Jie Liu, HongJie Shen, Zheng Wang, LiuJun Cao, Pin Wu, HongYing Chao, XuZhang Lu, ZhuXia Jia, MeiYu Chen, Xiaohui Cai
Publikováno v:
International journal of hematology. 116(1)
We report the co-mutations in AML with CEBPAWe retrospectively sequenced 112 genes in 302 patients with CEBPA① The average number of mutations in CEBPACEBPA