Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Hongyao She"'
Autor:
Jeffrey W. Johannes, Fiona Pachl, Amber Balazs, Tieguang Yao, C. Larner, Lisa McWilliams, Marianne Schimpl, Scott W. Martin, Kevin J. Embrey, Tom D. Heightman, Paul Hemsley, Jonathan P. Orme, Derek Barratt, Giuditta Illuzzi, Andrew Madin, Paolo Di Fruscia, Avipsa Ghosh, Martin J. Packer, Scott D. Edmondson, Elisabetta Leo, Xiaolan Zheng, Matthew D. Chuba, Xiaohui Pei, Mark J. O'Connor, Verity Talbot, Ke Zhang, Stephen Fawell, Elizabeth Underwood, Anna Staniszewska, Lina Liu, Lin Xue, Sonja J. Gill, Anders Gunnarsson, Andrew Pike, Susan E. Critchlow, Jeffrey G. Varnes, Andrew X. Zhang, Sébastien L. Degorce, J. Lane, Sudhir M. Hande, Hongyao She, Sabina Cosulich, Michal Bista
Publikováno v:
Journal of Medicinal Chemistry. 64:14498-14512
Poly-ADP-ribose-polymerase (PARP) inhibitors have achieved regulatory approval in oncology for homologous recombination repair deficient tumors including BRCA mutation. However, some have failed in combination with first-line chemotherapies, usually
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)
Abstract The railway rivet is one of the most important and easily damaged parts of the connection. If rivets develop cracks during the production process, their load-bearing capacity will be reduced, thereby increasing the risk of failure. Fluoresce
Externí odkaz:
https://doaj.org/article/cb3049eb08ee4416bfd057e66d642368
Autor:
Jing Tian, Enyu Shi, Chengzhi Fang, Yushen Chen, Xiaoliang Lin, Xiaolei Deng, Xinhua Yao, Hongyao Shen
Publikováno v:
IEEE Access, Vol 12, Pp 49904-49915 (2024)
The feed system is an important part of CNC machine tools, and its condition monitoring is mostly based on vibration signals measured by sensors. To remove the noise mixed in the signal, a joint denoising method based on variational mode decompositio
Externí odkaz:
https://doaj.org/article/7632adc8d8f44bba85633054a75d4d74
Publikováno v:
Virtual and Physical Prototyping, Vol 17, Iss 1, Pp 105-124 (2022)
Continuous tool-path is often chose to improve the deposition efficiency and surface accuracy of metal additive manufacturing, while it also causes large residual thermal stress, which will result in part deformation and performance degradation. This
Externí odkaz:
https://doaj.org/article/4bb6a9e157a34403a22c7148d1358a51
Publikováno v:
Materials & Design, Vol 206, Iss , Pp 109787- (2021)
Laser Powder-Bed Fusion (LPBF) of Mg-Al alloys is a promising way to additively manufacture Mg-Al alloy components. However, the grains of the LPBF-processed AZ91D Mg-Al alloys could be coarse. The grains might undergo columnar growth, which is less
Externí odkaz:
https://doaj.org/article/9834d5fcbe1742a5ad9e3c3d9271adc7
Publikováno v:
Advances in Polymer Technology, Vol 2020 (2020)
Injection molding is widely used in industries to produce polymeric products. At present, compound NURBS surfaces are commonly used to represent freeform surfaces in mold models. This work uses T-spline surface with extraordinary control points inste
Externí odkaz:
https://doaj.org/article/ccf4b5f5340e4740b7a5d98b981234b4
Publikováno v:
Materials, Vol 13, Iss 18, p 4157 (2020)
A three dimensional finite element model (FEM) was established to simulate the temperature distribution, flow activity, and deformation of the melt pool of selective laser melting (SLM) AZ91D magnesium alloy powder. The latent heat in phase transitio
Externí odkaz:
https://doaj.org/article/dc1f968723134581afdc2a7381dec75b
Publikováno v:
Applied Sciences, Vol 10, Iss 12, p 4322 (2020)
Gas metal arc welding (GMAW)-based additive manufacturing has the advantages of a high deposition rate, low cost, the production of a compact and dense microstructure in the cladding layer, and good mechanical properties, but the forming process is u
Externí odkaz:
https://doaj.org/article/6817a92a9aee4585bcb5dcee57a0702e
Publikováno v:
Applied Sciences, Vol 10, Iss 5, p 1716 (2020)
Great progress has been made in 2D color printing with inkjet technology, and mature related products have come out, but there still exists great developmental space in 3D color printing. Therefore, a new path planning method based on the offset curv
Externí odkaz:
https://doaj.org/article/6cace207e25e467eb972aa67ce3e4096
Publikováno v:
Applied Sciences, Vol 10, Iss 1, p 235 (2019)
Fused Deposition Modeling (FDM) additive manufacturing technology is widely applied in recent years. However, there are many defects that may affect the surface quality, accuracy, or even cause the collapse of the parts in the printing process. In th
Externí odkaz:
https://doaj.org/article/63b2e76b82dd4fd2960e78a59b6d7e80