Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Hongyan Sui"'
Autor:
Tomozumi Imamichi, Qian Chen, Bharatwaj Sowrirajan, Jun Yang, Sylvain Laverdure, Mayra Marquez, Anthony R. Mele, Catherine Watkins, Joseph W. Adelsberger, Jeanette Higgins, Hongyan Sui
Publikováno v:
PLoS ONE, Vol 18, Iss 11 (2023)
Externí odkaz:
https://doaj.org/article/2316374f4b0d42b0b2df35f61396e78e
Publikováno v:
iScience, Vol 25, Iss 11, Pp 105352- (2022)
Summary: Trace metals are essential for various physiological processes, but their roles in innate immunity have not been fully explored. Here, we found that manganese (Mn) significantly enhanced DNA-mediated IFN-α, IFN-β, and IFN-λ1 production. M
Externí odkaz:
https://doaj.org/article/3651dea7653a4b2d8e4574466f60f4fe
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Human Ku70 is a well-known endogenous nuclear protein involved in the non-homologous end joining pathway to repair double-stranded breaks in DNA. However, Ku70 has been studied in multiple contexts and grown into a multifunctional protein. In additio
Externí odkaz:
https://doaj.org/article/4b614317ef3f4197803631383a3269c9
Autor:
Weizhong Chang, Xiaoli Jiao, Hongyan Sui, Suranjana Goswami, Brad T. Sherman, Caroline Fromont, Juan Manuel Caravaca, Bao Tran, Tomozumi Imamichi
Publikováno v:
Viruses, Vol 14, Iss 3, p 536 (2022)
Herpes simplex virus type 2 (HSV-2) is a common causative agent of genital tract infections. Moreover, HSV-2 and HIV infection can mutually increase the risk of acquiring another virus infection. Due to the high GC content and highly repetitive regio
Externí odkaz:
https://doaj.org/article/9323458826054e8b8e135be82855170f
Publikováno v:
MethodsX, Vol 7, Iss , Pp 100890- (2020)
Innate immune response is insisted upon detection of foreign intracellular DNA or RNA derived from viruses and bacteria. This reaction is important to initiate an effective protective response for the host cells. This crucial step is induced by cytos
Externí odkaz:
https://doaj.org/article/1ed93201b70a4182a4572667ee98d8c0
Autor:
Qian Chen, Sanjay Swaminathan, De Yang, Lue Dai, Hongyan Sui, Jun Yang, Ronald L Hornung, Yanmei Wang, Da Wei Huang, Xiaojun Hu, Richard A Lempicki, Tomozumi Imamichi
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59194 (2013)
IL-27, a member of the IL-12 family of cytokines, plays an important and diverse role in the function of the immune system. Whilst generally recognized as an anti-inflammatory cytokine, in addition IL-27 has been found to have broad anti-viral effect
Externí odkaz:
https://doaj.org/article/0241d69ffb844b4a812d70d336232c62
Autor:
Hongyan Sui, Tomozumi Imamichi
Publikováno v:
Methods in Molecular Biology ISBN: 9781071628461
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::495be77da3bcb58d16268ae467b405aa
https://doi.org/10.1007/978-1-0716-2847-8_1
https://doi.org/10.1007/978-1-0716-2847-8_1
Autor:
Hongyan, Sui, Tomozumi, Imamichi
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2599
DNA-protein interactions (DPIs) are critical to all living organisms, particularly in the regulation of gene expression, replication, packing, recombination, and DNA repair, as well as RNA transport and translation. Many laboratory techniques have be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2f0cf7595dce83c95f830f871244ea36
https://pubmed.ncbi.nlm.nih.gov/36427138
https://pubmed.ncbi.nlm.nih.gov/36427138
Publikováno v:
Immunology
Summary We have previously identified that human Ku70, a nuclear protein, serves as a cytosolic DNA sensor. Upon transfection with DNA or infection with DNA virus, Ku70 translocates from the nucleus into the cytoplasm and then predominately induces i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01290cabf18c9852c8222d96d7ecf074
http://europepmc.org/articles/PMC8207419
http://europepmc.org/articles/PMC8207419
Autor:
Sylvain Laverdure, Tomozumi Imamichi, Hongyan Sui, Robin Dewar, Qian Chen, Helene Highbarger, John G. Bernbaum, Ming Hao, Weizhong Chang, H. Clifford Lane, Jun Yang
Publikováno v:
J Virol
Recently, a genome-wide association study using plasma HIV RNA from antiretroviral therapy-naive patients reported that 14 naturally occurring nonsynonymous single-nucleotide polymorphisms (SNPs) in HIV derived from antiretrovirus drug-naive patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cab5ad1fb4146281aa26e5017a95450
https://europepmc.org/articles/PMC8577372/
https://europepmc.org/articles/PMC8577372/