Zobrazeno 1 - 10
of 206
pro vyhledávání: '"Hongxin Deng"'
Autor:
Wenshuang Wang, Yanhong Ji, Zhexu Dong, Zheran Liu, Shuang Chen, Lei Dai, Xiaolan Su, Qingyuan Jiang, Hongxin Deng
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-24 (2024)
Abstract Background Neural Tube Defects (NTDs) are congenital malformations of the central nervous system resulting from the incomplete closure of the neural tube during early embryonic development. Neuroinflammation refers to the inflammatory respon
Externí odkaz:
https://doaj.org/article/c9fbe556209f490d9b8874959c145d19
Autor:
Lei He, Shilong Li, Yan Huang, Yuxing Zhu, Lingzi Fan, Hongwei Zhang, Xiaofang Hou, Xiaoxin Li, Hongxin Deng, Xueli Guo, Chunxiao Liu, Chen Hu, Bing Cao
Publikováno v:
Frontiers in Psychiatry, Vol 15 (2024)
BackgroundMajor depressive disorder (MDD) pathogenesis may involve metalloids in a significant way. The aim of our study was to identify potential links between MDD and metalloid elements [boron (B), germanium (Ge), arsenic (As), antimony (Sb)].Metho
Externí odkaz:
https://doaj.org/article/fdf02c09fce84511a4fe4b73b0aae62c
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-19 (2023)
Abstract Colorectal cancer (CRC) is the third most common cancer worldwide. One of the main causes of colorectal cancer is inflammatory bowel disease (IBD), which includes ulcerative colitis (UC) and Crohn’s disease (CD). Intestinal epithelial cell
Externí odkaz:
https://doaj.org/article/b2bf52be51af4f85b56c226efed7aa32
Autor:
Yi Liu, Yanhong Ji, Ruiyi Jiang, Chao Fang, Gang Shi, Lin Cheng, Yinan Zuo, Yixin Ye, Xiaolan Su, Junshu Li, Huiling Wang, Yuan Wang, Yi Lin, Lei Dai, Shuang Zhang, Hongxin Deng
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-17 (2023)
Abstract Cancer and impaired tissue wound healing with ageing are closely related to the quality of life of the elderly population. Given the increased incidence of cancer and the population ageing trend globally, it is very important to explore how
Externí odkaz:
https://doaj.org/article/3f9fd583066344808febb66bc0e8aa63
Autor:
Yunqi Yao, Lin Zhang, Fuyi Cheng, Qingyuan Jiang, Yixin Ye, Yushuang Ren, Yuting He, Dongsheng Su, Lin Cheng, Gang Shi, Lei Dai, Hongxin Deng
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Background Decompensated liver cirrhosis (DLC), a terminal-stage complication of liver disease, is a major cause of morbidity and mortality in patients with hepatopathies. Human umbilical cord mesenchymal stem cell (hUCMSC) therapy has emerg
Externí odkaz:
https://doaj.org/article/65e9f66dd39f4bc89026ec3b1e50a1b6
Autor:
Jing Su, Xiu Jin, Kaiqin She, Yi Liu, Li Song, Qinyu Zhao, Jianlu Xiao, Ruiting Li, Hongxin Deng, Fang Lu, Yang Yang
Publikováno v:
Molecular Biomedicine, Vol 4, Iss 1, Pp 1-14 (2023)
Abstract Mucopolysaccharidosis type I (MPS I) is a severe disease caused by loss-of-function mutation variants in the α-L-iduronidase (Idua) gene. In vivo genome editing represents a promising strategy to correct Idua mutations, and has the potentia
Externí odkaz:
https://doaj.org/article/50438126a6464129b2b191933cd50900
Autor:
Yixin Ye, Xiaomei Zhang, Dongsheng Su, Yushuang Ren, Fuyi Cheng, Yunqi Yao, Gang Shi, Yanhong Ji, Shuang Chen, Pengyi Shi, Lei Dai, Xiaolan Su, Hongxin Deng
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-20 (2022)
Abstract Background Inflammatory bowel diseases (IBD) are chronic relapsing–remitting inflammatory diseases of the gastrointestinal tract that are typically categorized into two subtypes: Crohn's disease (CD) and ulcerative colitis (UC). Although M
Externí odkaz:
https://doaj.org/article/bf7abc0cd96149778e9399d0c7cdb654
Autor:
Hongxin Deng, Lei He, Chong Wang, Teng Zhang, Hua Guo, Hongwei Zhang, Yanning Song, Bangtao Chen
Publikováno v:
BMC Psychiatry, Vol 22, Iss 1, Pp 1-12 (2022)
Abstract Background The pathophysiological mechanisms of aggression are manifold and they may closely interconnect. Current study aimed to determine the gut microbiota and its metabolites, and clarify their correlations with inflammation, oxidation,
Externí odkaz:
https://doaj.org/article/b059acd516e447549baaf948537d4ae8
Autor:
Guimin Zhang, Binrui Liu, Yun Yang, Shuo Xie, Lingcheng Chen, Hui Luo, Jian Zhong, Yinhao Wei, Fengzhu Guo, Jia Gan, Fan Zhu, Lin Xu, Qiqi Li, Yuge Shen, Huajin Zhang, Yan Liu, Rong Li, Hongxin Deng, Hanshuo Yang
Publikováno v:
iScience, Vol 26, Iss 8, Pp 107370- (2023)
Summary: Mitochondria play important roles in angiogenesis. However, the mechanisms remain elusive. In this study, we found that mitochondrial ubiquinol-cytochrome c reductase complex assembly factor 3 (UQCC3) is a key regulator of angiogenesis. TALE
Externí odkaz:
https://doaj.org/article/a7b816bafa49449090f9ea17f4f28d9c
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Glioblastoma is a malignant tumor with the highest morbidity and mortality in the central nervous system. Conventional surgical resection combined with radiotherapy or chemotherapy has a high recurrence rate and poor prognosis. The 5-year survival ra
Externí odkaz:
https://doaj.org/article/9a90e28ff85d4cd78ab38ef09ead9154