Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Hongxiao Jiao"'
Autor:
Jinjin Li, Qun Ye, Hongxiao Jiao, Wanyao Wang, Kai Zhang, Chen Chen, Yuan Zhang, Shuzhi Feng, Ximo Wang, Yubao Chen, Huailin Gao, Fengjiang Wei, Wei-Dong Li
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
AimsWe aimed to construct a prediction model of type 2 diabetes mellitus (T2DM) in a Han Chinese cohort using a genetic risk score (GRS) and a nongenetic risk score (NGRS).MethodsA total of 297 Han Chinese subjects who were free from type 2 diabetes
Externí odkaz:
https://doaj.org/article/c7b3681a2e55412d8a280b3fd4d80cf2
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
As a marker for glomerular filtration, plasma cystatin C level is used to evaluate kidney function. To decipher genetic factors that control the plasma cystatin C level, we performed genome-wide association and pathway association studies using Unite
Externí odkaz:
https://doaj.org/article/ba9ad880ad904e5596550f2024377d96
Autor:
Hongxiao Jiao, Yong Zang, Miaomiao Zhang, Yuan Zhang, Yaogang Wang, Kai Wang, R. Arlen Price, Wei-Dong Li
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Objective: We investigated gene interactions (epistasis) for body mass index (BMI) in a European-American adult female cohort via genome-wide interaction analyses (GWIA) and pathway association analyses.Methods: Genome-wide pairwise interaction analy
Externí odkaz:
https://doaj.org/article/66cfa913fa194f86b6ae8562907eb536
Autor:
Hongxiao Jiao, Kai Wang, Fuhua Yang, Struan F A Grant, Hakon Hakonarson, R Arlen Price, Wei-Dong Li
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0134923 (2015)
Pathway-based analysis as an alternative approach can provide complementary information to single-marker genome-wide association studies (GWASs), which always ignore the epistasis and does not have sufficient power to find rare variants. In this stud
Externí odkaz:
https://doaj.org/article/fdf02782896c4d32a52660c91ac21648
Autor:
Hongxi Yang, Chenjie Xu, Yangyang Cheng, Li Sun, Hongxiao Jiao, Shu Li, Zhi Cao, Yaogang Wang, Weidong Li, Yuan Zhang, Ju Wang
Publikováno v:
Reviews in endocrinemetabolic disorders. 22(2)
Both genetic and nongenetic factors have been found to be associated with type 2 diabetes, however, the correlation between them is still unclear. In the present study, we aimed to fully decipher the nongenetic and genetic factor association network
Autor:
Clarence K. Zhang, R. Arlen Price, Hakon Hakonarson, Hongyu Zhao, Kai Wang, Hongxiao Jiao, Struan F.A. Grant, Weidong Li, Joseph T. Glessner
Publikováno v:
Obesity. 21:E490-E494
Objective To identify plasma uric acid-related genes in extremely obese and normal weight individuals using genome-wide association studies (GWASs). Design and Methods Using genotypes from a GWAS focusing on obesity and thinness, quantitative trait a
Autor:
Ruili Dang, Pengfei Xu, Xueyuan Zhou, Hongxiao Jiao, Xiaoxue Gong, Mimi Tang, Yuanyuan Liu, Pei Jiang
Publikováno v:
European journal of nutrition. 57(3)
Depression is frequently associated with inflammation, whereas omega-3 polyunsaturated fatty acids (PUFAs) primarily found in fish oil possess anti-inflammatory properties. Although converging studies suggest an antidepressant effect of PUFAs, there
Autor:
Kai Wang, Hongxiao Jiao, Struan F.A. Grant, Hakon Hakonarson, R. Arlen Price, Rexford S. Ahima, Fuhua Yang, Weidong Li
Publikováno v:
Scientific Reports
Pathway-based analysis as an alternative and effective approach to identify disease-related genes or loci has been verified. To decipher the genetic background of plasma adiponectin levels, we performed genome wide pathway-based association studies i
Autor:
Baocheng Chang, Mingqin Chang, Huina Qiu, Yuhua Wang, Jingbo Li, Weidong Li, Yongjun Chen, Long Su, Ping Yu, Jia Yu Lv, Wentao Shi, Fengjiang Wei, Hongxiao Jiao, Fuhua Yang, Hongling Han, Ran Li, Jing-na Lin, Jianli Tian, Shen Li, Chunyou Cai, Lei Zou, Jingmin Shi, Mingshan Li, Hong Zhang, Shuzhi Feng, Ning Sun, Liming Chen, C. Ling, Shiying Liu
Publikováno v:
Scientific Reports
To study associations between type 2 diabetes (T2DM) candidate genes and microvascular complications of diabetes (MVCDs), we performed case-control association studies for both T2DM and MVCDs in Han Chinese subjects. We recruited 1,939 unrelated Han
Autor:
Struan F.A. Grant, Weidong Li, Hakon Hakonarson, Fuhua Yang, Kai Wang, R. Arlen Price, Hongxiao Jiao
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 8, p e0134923 (2015)
PLoS ONE, Vol 10, Iss 8, p e0134923 (2015)
Pathway-based analysis as an alternative approach can provide complementary information to single-marker genome-wide association studies (GWASs), which always ignore the epistasis and does not have sufficient power to find rare variants. In this stud