Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Hongwon Kim"'
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
Brain organoids have become a valuable tool for studying human brain development, disease modeling, and drug testing. However, generating brain organoids with mature neurons is time-intensive and often incomplete, limiting their utility in studying a
Externí odkaz:
https://doaj.org/article/f8b3b788ac504b06843c46e77f060424
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Brain organoids, which are three-dimensional cell culture models, have the ability to mimic certain structural and functional aspects of the human brain. However, creating these organoids can be a complicated and difficult process due to var
Externí odkaz:
https://doaj.org/article/35c1b4aaa9bc49ffbc93e09ae4cc7a2c
Autor:
Hanseul Park, Byounggook Cho, Hongwon Kim, Takashi Saito, Takaomi C. Saido, Kyoung-Jae Won, Jongpil Kim
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Oligodendrocytes have been increasingly shown to be involved in Alzheimer’s disease (AD). Here, the authors perform single-cell RNA-sequencing on APP NL-G-F mice and describe a disease-associated oligodendrocyte (DAO) population. They find inhibiti
Externí odkaz:
https://doaj.org/article/ddf21b0e2134438cac005033cc9fdd4a
Publikováno v:
Translational Neurodegeneration, Vol 11, Iss 1, Pp 1-14 (2022)
Abstract Background The ε4 allele of apolipoprotein E (APOE ε4) is the strongest known genetic risk factor for late-onset Alzheimer’s disease (AD), associated with amyloid pathogenesis. However, it is not clear how APOE ε4 accelerates amyloid-be
Externí odkaz:
https://doaj.org/article/1a3f8e9ce44a408ba720f6c8ec37cea3
Autor:
Hongwon Kim, Sumin Kim, Sang-jun Park, Gwoncheol Park, Hakdong Shin, Myeong Soo Park, Jongpil Kim
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Recent evidence indicates that gut microbiota could interact with the central nervous system and affect brain function, including cognition and memory. In this study, we investigated whether Bifidobacterium bifidum BGN4 (B. bifidum BGN4) and Bifidoba
Externí odkaz:
https://doaj.org/article/96d2fcd26bf943148450b18eb335e4a1
Autor:
Hongwon Kim, Hyeok Ju Park, Hwan Choi, Yujung Chang, Hanseul Park, Jaein Shin, Junyeop Kim, Christopher J. Lengner, Yong Kyu Lee, Jongpil Kim
Publikováno v:
Stem Cell Reports, Vol 12, Iss 3, Pp 518-531 (2019)
Summary: Recent advances in generating three-dimensional (3D) organoid systems from stem cells offer new possibilities for disease modeling and drug screening because organoids can recapitulate aspects of in vivo architecture and physiology. In this
Externí odkaz:
https://doaj.org/article/3bfa8e2be2c640df9fbbbf4da234bbe2
Publikováno v:
Journal of the Korea Institute of Military Science and Technology. 26:72-82
The EOTS(Electro Optical Tracking System) must have stabilization performance to provide high-quality images under disturbance environment. In this paper, we present a controller that can minimize the LOS error and has a simple structure. Hence, to e
Autor:
Hongwon, Kim, Jaein, Shin, Sumin, Kim, Siyoung, Kim, Byounggook, Cho, Sang-Jun, Park, Gwoncheol, Park, Hakdong, Shin, Myeong Soo, Park, Jongpil, Kim
Publikováno v:
Biochemical and Biophysical Research Communications. 603:41-48
An increasing number of studies have indicated that alterations in gut microbiota affect brain function, including cognition and memory ability, via the gut-brain axis. In this study, we aimed to determine the protective effect of Bifidobacterium bif
Autor:
Pyeong Seob Yang, Hongwon Kim
Publikováno v:
SSRN Electronic Journal.