Zobrazeno 1 - 10
of 256
pro vyhledávání: '"Hongwei Xia"'
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-17 (2024)
Abstract CircRNAs are a type of circular non-coding RNA whose associations with drug sensitivities have been demonstrated in recent studies. Due to the high cost of biomedical experiments for detecting the associations between circRNAs and drug sensi
Externí odkaz:
https://doaj.org/article/8ac5e609ef494abeb8e3dace9e24c526
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
BackgroundPostpartum urinary incontinence (UI) is a serious condition that significantly affects the quality of life. Several studies have demonstrated that it is associated with pelvic floor dysfunction. This study aimed to develop and validate a UI
Externí odkaz:
https://doaj.org/article/1f07d9f270224997a57ea7d49528b408
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 5, Pp 1895-1923 (2024)
RAS mutations occur in approximately 30% of tumors worldwide and have a poor prognosis due to limited therapies. Covalent targeting of KRAS G12C has achieved significant success in recent years, but there is still a lack of efficient therapeutic appr
Externí odkaz:
https://doaj.org/article/0fc4b368cc7a4c6c8fecd29958fa9a02
Publikováno v:
npj Biofilms and Microbiomes, Vol 10, Iss 1, Pp 1-15 (2024)
Abstract A high-fat diet (HFD) may be linked to an increased colorectal cancer (CRC) risk. Stem cell proliferation and adipokine release under inflammatory and obese conditions are the main factors regulating CRC progression. Furthermore, alterations
Externí odkaz:
https://doaj.org/article/46528a726044410baa6eb3420e2f109f
Publikováno v:
IET Control Theory & Applications, Vol 17, Iss 13, Pp 1752-1767 (2023)
Abstract An accurate description of the relative motion of satellites is critical for space missions in the complex geostationary earth orbit space environment. Here, a new relative motion model is established considering major perturbations. To avoi
Externí odkaz:
https://doaj.org/article/949f3cd0f7ec4ffb98076f9998273487
Publikováno v:
Energies, Vol 17, Iss 14, p 3559 (2024)
In recent years, with the increase in environmental awareness, people have become more and more concerned about the effectiveness with which coal burns. Laser-induced breakdown spectroscopy (LIBS) has become an important way of coal elemental analysi
Externí odkaz:
https://doaj.org/article/6784099675fc4e31b9a1a80570d3b33f
Publikováno v:
Applied Sciences, Vol 14, Iss 4, p 1606 (2024)
As an extremely important energy source, improving the efficiency and accuracy of coal classification is important for industrial production and pollution reduction. Laser-induced breakdown spectroscopy (LIBS) is a new technology for coal classificat
Externí odkaz:
https://doaj.org/article/26c51c2cd1d94590801806c55d8f0e75
Publikováno v:
Cell Death and Disease, Vol 13, Iss 7, Pp 1-15 (2022)
Abstract Aggresome formation is a protective cellular response to counteract proteasome dysfunction by sequestering misfolded proteins and reducing proteotoxic stress. Autophagic degradation of the protein aggregates is considered to be a key compens
Externí odkaz:
https://doaj.org/article/8279cea700cb4df680e9e8d4c40c5b7f
Publikováno v:
Molecular Cancer, Vol 20, Iss 1, Pp 1-17 (2021)
Abstract Colorectal cancer (CRC) is a heterogeneous disease at the cellular and molecular levels. Kirsten rat sarcoma (KRAS) is a commonly mutated oncogene in CRC, with mutations in approximately 40% of all CRC cases; its mutations result in constitu
Externí odkaz:
https://doaj.org/article/a5cb9fa2bdcc4009ba782630d37a3d2e
Targeting SERT promotes tryptophan metabolism: mechanisms and implications in colon cancer treatment
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-17 (2021)
Abstract Background Serotonin signaling has been associated with tumorigenesis and tumor progression. Targeting the serotonin transporter to block serotonin cellular uptake confers antineoplastic effects in various tumors, including colon cancer. How
Externí odkaz:
https://doaj.org/article/023109eab6204f13ac94e68db6d7d014