Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Hongwei Dou"'
Autor:
Zezhong Zheng, Lei Xu, Yangbin Gao, Hongwei Dou, Yixuan Zhou, Xu Feng, Xiangjun He, Zhen Tian, Lingling Song, Guolong Mo, Jiapan Hu, Hongye Zhao, Hongjiang Wei, George M. Church, Luhan Yang
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 7 (2024)
ABSTRACT African swine fever (ASF) is a highly fatal viral disease that poses a significant threat to domestic pigs and wild boars globally. In our study, we aimed to explore the potential of a multiplexed CRISPR-Cas system in suppressing ASFV replic
Externí odkaz:
https://doaj.org/article/aa728c5685664910bbb4738257374ead
Autor:
Huan Liu, Yong Li, Qiang Wei, Chunxin Liu, Lars Bolund, Gábor Vajta, Hongwei Dou, Wenxian Yang, Ying Xu, Jing Luan, Jun Wang, Huanming Yang, Nicklas Heine Staunstrup, Yutao Du
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76098 (2013)
Minipigs have become important biomedical models for human ailments due to similarities in organ anatomy, physiology, and circadian rhythms relative to humans. The homeostasis of circadian rhythms in both central and peripheral tissues is pivotal for
Externí odkaz:
https://doaj.org/article/fb16aa19bbcd42aab18cc51ca70f86a8
Autor:
Peng Zhang, Peng Liu, Hongwei Dou, Lei Chen, Longxin Chen, Lin Lin, Pingping Tan, Gabor Vajta, Jianfeng Gao, Yutao Du, Runlin Z Ma
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e55941 (2013)
Technology of somatic cell nuclear transfer (SCNT) has been adapted worldwide to generate transgenic animals, although the traditional procedure relies largely on instrumental micromanipulation. In this study, we used the modified handmade cloning (H
Externí odkaz:
https://doaj.org/article/123eef976a604e398789322777c8db94
Autor:
Zezhong Zheng, Lei Xu, Hongwei Dou, Yixuan Zhou, Xu Feng, Xiangjun He, Zhen Tian, Lingling Song, Yangbin Gao, Guolong Mo, Jiapan Hu, Hongye Zhao, Hongjiang Wei, George M. Church, Luhan Yang
African Swine Fever (ASF) is a viral disease with exceptionally high lethality in domestic pigs and wild boar worldwide1, 2, without any effective vaccine or drug to prevent its spread. In this study, we established a multiplexable CRISPR-Cas-gRNA sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cadfded8da190021e9c1cf299db2d815
https://doi.org/10.1101/2022.06.09.495443
https://doi.org/10.1101/2022.06.09.495443
Autor:
Violette Paragas, Jacob V. Layer, Marc Güell, William F. Westlin, Luhan Yang, Juan Xiong, Weilin Wang, Shengyi Mao, Yinan Kan, Ranjith P. Anand, Deling Jiao, Zhongquan Sun, Mengyuan Xu, George M. Church, Lydia Lamriben, Xiaobin Song, Yu Luo, Lei Le, Hong-Ye Zhao, Hong-Jiang Wei, Michele Youd, Mailin Li, Yangbin Gao, Qi Zhang, Hongwei Dou, Dharmendra Goswami, Haydy George, Meng Yang, Yanan Yue, Yixuan Zhou, Zhuo Li, Shi Yun Wang, Lingling Song, James F. Markmann, Yuan Ding, Wenning Qin, Xueqiong Wang, Jiajia Wu, Tien Dat Nguyen, Xin Fang, Jianxiong Guo, Weihong Xu
Publikováno v:
Nature Biomedical Engineering. 5:134-143
The clinical applicability of porcine xenotransplantation-a long-investigated alternative to the scarce availability of human organs for patients with organ failure-is limited by molecular incompatibilities between the immune systems of pigs and huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a4620e6209389e804949c3e722376a6
https://doi.org/10.1038/s41551-020-00613-9
https://doi.org/10.1038/s41551-020-00613-9
Autor:
Xuechao Tang, Hong Wu, Pan Li, Ni Zhu, Yuan Bai, Xudong Xu, Xianxian Zhao, Wenfeng Xiong, Hongwei Dou, Yong-Wen Qin
Publikováno v:
International Heart Journal. 60:181-184
We present a rare case of thrombus adhering to the puncture site of the atrial septum during left atrial appendage closure. By discussing the case, we suggest that some preventive measurements be taken during left atrial appendage closure and that co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bc69150830afbd5ee684d4dfd7453b1
https://doi.org/10.1536/ihj.17-591
https://doi.org/10.1536/ihj.17-591
Autor:
Jing Li, Xuyi Lin, Wenbin Chen, Xing-Ju Zhang, Ting-Ting Zhang, Jie Li, Lin Lin, Tianbin Liu, Xi Xiang, Hongwei Dou, Ying Gu, Xuan Dong, Lin Li, Hai-Xi Sun, Lei Chen
Publikováno v:
Liu, T, Li, J, Dou, H, Xiang, X, Chen, W, Zhang, T, Li, L, Zhang, X, Dong, X, Chen, L, Lin, X, Li, J, Sun, H-X, Gu, Y & Lin, L 2020, ' Low-Concentration Essential Amino Acids in PZM-3 Improve the Developmental Competence of Porcine Embryos Produced by Handmade Cloning ', Cellular reprogramming, vol. 22, no. 6, pp. 282-290 . https://doi.org/10.1089/cell.2020.0036
Essential amino acids (EAA) of inappropriate concentration have been reported to compromise the development of embryo. This study aimed to investigate the effect of EAA on the developmental competence of porcine embryos produced by either handmade cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::870bd2f45aa380de921da60961a9451d
https://pure.au.dk/portal/da/publications/lowconcentration-essential-amino-acids-in-pzm3-improve-the-developmental-competence-of-porcine-embryos-produced-by-handmade-cloning(1431ff24-6688-49bf-b4df-fb284e9f60c7).html
https://pure.au.dk/portal/da/publications/lowconcentration-essential-amino-acids-in-pzm3-improve-the-developmental-competence-of-porcine-embryos-produced-by-handmade-cloning(1431ff24-6688-49bf-b4df-fb284e9f60c7).html
Autor:
Ranjith P. Anand, Yu Luo, Shi Yun Wang, Hong-Jiang Wei, Juan Xiong, Deling Jiao, Violette Paragas, Yinan Kan, Yangbin Gao, Wenning Qin, Tien Dat Nguyen, George M. Church, Hongwei Dou, Jianxiong Guo, Yixuan Zhou, Shengyi Mao, Weihong Xu, Marc Güell, Jacob V. Layer, Hong-Ye Zhao, Mailin Li, Xin Fang, Xiaobin Song, Qi Zhang, Lei Le, William F. Westlin, Luhan Yang, Zhuo Li, Lingling Song, Xueqiong Wang, Jiajia Wu, Yuan Ding, James F. Markmann, Lydia Lamriben, Michele Youd, Weilin Wang, Zhongquan Sun, Mengyuan Xu, Meng Yang, Dharmendra Goswami, Yanan Yue, Haydy George
Xenotransplantation, specifically the use of porcine organs for human transplantation, has long been sought after as an alternative for patients suffering from organ failure. However, clinical application of this approach has been impeded by two main
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45a3dbf2be5e71b1ce5cbdd292ed0d75
https://doi.org/10.1101/2019.12.17.876862
https://doi.org/10.1101/2019.12.17.876862
Autor:
Lingxiao Wang, Xian Guo, Xudong Xu, Yong-Wen Qin, Tong Kan, Xianxian Zhao, Pan Li, Hongwei Dou, Jian Na
Publikováno v:
Pediatric cardiology. 41(4)
Transcatheter closure of large atrial septal defects (ASDs) remains controversial. The aim of this study was to evaluate the feasibility and safety of transthoracic echocardiography (TTE)-guided transcatheter closure of large ASDs. Patients with larg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aad7edfd966b655f45bcd4845b4c5b0a
https://pubmed.ncbi.nlm.nih.gov/32006083
https://pubmed.ncbi.nlm.nih.gov/32006083
Autor:
Ling Yang, Yonglun Luo, Xiaoguang Pan, Conghui Li, Michał Nodzyński, Xue Liang, Peng Han, Guangdong Tong, Yufeng Xing, Xiuqing Zhang, Lin Lin, Xin Liu, Hongwei Dou, Lars Bolund, Yonghui Dang, Trine Skov Petersen, Kunli Qu, Xi Xiang, Lidan Luo
Publikováno v:
Xiang, X, Luo, L, Nodzyński, M, Li, C, Han, P, Dou, H, Petersen, T S, Liang, X, Pan, X, Qu, K, Yang, L, Dang, Y, Liu, X, Bolund, L, Zhang, X, Tong, G, Xing, Y, Luo, Y & Lin, L 2019, ' LION : a simple and rapid method to achieve CRISPR gene editing ', Cellular and Molecular Life Sciences, vol. 76, no. 13, pp. 2633-2645 . https://doi.org/10.1007/s00018-019-03064-x
The RNA-guided CRISPR-Cas9 technology has paved the way for rapid and cost-effective gene editing. However, there is still a great need for effective methods for rapid generation and validation of CRISPR/Cas9 gRNAs. Previously, we have demonstrated t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a417e83f489a9358f572042196b4a4ce
https://pure.au.dk/portal/da/publications/lion(89e0b841-d85f-4f2f-b1b4-bf2386e53040).html
https://pure.au.dk/portal/da/publications/lion(89e0b841-d85f-4f2f-b1b4-bf2386e53040).html