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pro vyhledávání: '"Honguang Zhu"'
Autor:
Mengtao Xiao, Shimin Zhao, Hui Yang, Dan Ye, Wei Xu, Lixia Liu, Huaipeng Lin, Ying Liu, Honguang Zhu, Kun-Liang Guan, Chen Yang, Shenghong Ma, Yue Xiong, Yanhui Xu
Publikováno v:
Genes & Development. 26:1326-1338
Two Krebs cycle genes, fumarate hydratase (FH) and succinate dehydrogenase (SDH), are mutated in a subset of human cancers, leading to accumulation of their substrates, fumarate and succinate, respectively. Here we demonstrate that fumarate and succi