Zobrazeno 1 - 10
of 1 155
pro vyhledávání: '"Hongtao, Yu"'
Autor:
Hongtao Yu, Sebastian Ueckert, Lina Zhou, Jenny Cheng, Darren Robertson, Lars Hansen, Armando Flor, Victoria Parker, Bengt Hamrén, Anis A. Khan
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 13, Iss 9, Pp 1582-1594 (2024)
Abstract Cotadutide is a dual glucagon‐like peptide‐1 (GLP‐1)/glucagon receptor agonist. Gastrointestinal adverse effects are known to be associated with GLP‐1 receptor agonism and can be mitigated through tolerance development via a gradual
Externí odkaz:
https://doaj.org/article/46ab7d9753df4ffa8185e2c0d7b25270
Autor:
Ruyu Yan, Dan Liu, Hongjuan Guo, Minxia Liu, Dongjin Lv, Benny Björkblom, Mingsong Wu, Hongtao Yu, Hao Leng, Bingxiao Lu, Yuxiang Li, Miaomiao Gao, Tomas Blom, Kecheng Zhou
Publikováno v:
Cell Death and Disease, Vol 15, Iss 6, Pp 1-18 (2024)
Abstract Non-small cell lung cancer (NSCLC) is a leading cause of cancer-related deaths worldwide, necessitating the identification of novel therapeutic targets. Lysosome Associated Protein Transmembrane 4B (LAPTM4B) is involved in biological process
Externí odkaz:
https://doaj.org/article/3b6fe8b59b944394b039984218dd365c
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
IntroductionEndothelin-1 (ET-1) regulates renal and vascular function, but the clinical utility of selective ETA receptor antagonists has been limited due to associated fluid retention. The mechanisms underlying fluid retention remain poorly understo
Externí odkaz:
https://doaj.org/article/35527bed2919432ba86cbe10281ef248
Autor:
Haoruo Jia, Ziyuan Zheng, Jining Qu, Hongtao Yu, Zhoujun Zhu, Qingda Lu, Fei Su, Yating Yang, Tongtong Feng, Qiang Jie
Publikováno v:
Heliyon, Vol 10, Iss 18, Pp e38057- (2024)
Although Zeolitic Imidazolate Framework-8 (ZIF-8) shows significant promise in chemodynamic therapy of bacterial infections due to its large specific surface area and enzyme-like activity, it still faces a considerable gap compared to natural enzymes
Externí odkaz:
https://doaj.org/article/8f851757a57d4adbbfa9aa2f4f2dd8a0
Publikováno v:
Journal of Materials Research and Technology, Vol 30, Iss , Pp 2968-2976 (2024)
Carbon fibre dispersion exerts a critical influence on the characteristics of carbon fibre-reinforced cement mortars (CFRCMs). This study accordingly investigated the dispersion of chopped carbon fibres (CCFs) in mortar using physical experiments wit
Externí odkaz:
https://doaj.org/article/2d4f7921370c41a983cf9369626f35a0
Autor:
Lijing Zhang, Xuping Xie, Hannan Luo, Runtong Qian, Yang Yang, Hongtao Yu, Jing Huang, Pei-Yong Shi, Qi Hu
Publikováno v:
Cell Discovery, Vol 10, Iss 1, Pp 1-14 (2024)
Abstract Drug resistance poses a significant challenge in the development of effective therapies against SARS-CoV-2. Here, we identified two double mutations, M49K/M165V and M49K/S301P, in the 3C-like protease (3CLpro) that confer resistance to a nov
Externí odkaz:
https://doaj.org/article/b44f440683454d9aba992e81fbac8de0
Publikováno v:
Advances in Mechanical Engineering, Vol 16 (2024)
Contactors are extensively utilized in the control field. Enhancing the response speed and reducing mechanical tremors during switching-in hold great significance in improving contactor’s reliability. A novel A.C. contactor suitable for low-voltage
Externí odkaz:
https://doaj.org/article/6b5edd31bb61410fa5f4a5156b4bffe9
Publikováno v:
IEEE Photonics Journal, Vol 16, Iss 2, Pp 1-6 (2024)
Satellite optical communication networks have become a promising core network structure, surpassing 5G and 6G, and are expected to realize seamless connections between terrestrial and non-terrestrial networks. Constructing an optical satellite networ
Externí odkaz:
https://doaj.org/article/e57b213fa903478c898cc775ed31c743
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/7021361a35584d03ac426bffb6e53f3d
Publikováno v:
Advanced Intelligent Systems, Vol 6, Iss 5, Pp n/a-n/a (2024)
Vulnerability to adversarial examples poses a significant challenge to the secure application of deep neural networks. Adversarial training and its variants have shown great potential in addressing this problem. However, such approaches, which direct
Externí odkaz:
https://doaj.org/article/34294be038aa4bdda93778626eadcbff