Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Hongshuo, Song"'
Autor:
Manukumar Honnayakanahalli Marichannegowda, Saini Setua, Meera Bose, Eric Sanders-Buell, David King, Michelle Zemil, Lindsay Wieczorek, Felisa Diaz-Mendez, Nicolas Chomont, Rasmi Thomas, Leilani Francisco, Leigh Anne Eller, Victoria R. Polonis, Sodsai Tovanabutra, Alonso Heredia, Yutaka Tagaya, Nelson L. Michael, Merlin L. Robb, Hongshuo Song
Publikováno v:
EBioMedicine, Vol 109, Iss , Pp 105410- (2024)
Summary: Background: Nearly all transmitted/founder (T/F) HIV-1 are CCR5 (R5)-tropic. While previous evidence suggested that CXCR4 (X4)-tropic HIV-1 are transmissible, virus detection and characterization were not at the earliest stages of acute infe
Externí odkaz:
https://doaj.org/article/cb0d23262dfb444090a7d9f07063396f
Autor:
Hélène Le Buanec, Valérie Schiavon, Marine Merandet, Alexandre How-Kit, Hongshuo Song, David Bergerat, Céline Fombellida-Lopez, Armand Bensussan, Jean-David Bouaziz, Arsène Burny, Gilles Darcis, Mohammad M. Sajadi, Shyamasundaran Kottilil, Daniel Zagury, Robert C. Gallo
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-13 (2024)
Abstract Background Among people living with HIV, elite controllers (ECs) maintain an undetectable viral load, even without receiving anti-HIV therapy. In non-EC patients, this therapy leads to marked improvement, including in immune parameters, but
Externí odkaz:
https://doaj.org/article/7a6160af375a4badbc2386bf1f9eaf4f
Autor:
Hélène Le Buanec, Valérie Schiavon, Marine Merandet, Alexandre How-Kit, David Bergerat, Céline Fombellida-Lopez, Armand Bensussan, Jean-David Bouaziz, Arsène Burny, Gilles Darcis, Hongshuo Song, Mohammad M. Sajadi, Shyamasundaran Kottilil, Robert C. Gallo, Daniel Zagury
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-12 (2024)
Abstract Background A complete understanding of the different steps of HIV replication and an effective drug combination have led to modern antiretroviral regimens that block HIV replication for decades, but these therapies are not curative and must
Externí odkaz:
https://doaj.org/article/50dcb996f0ff4a6b933ff6c1463ac569
Autor:
Hongshuo Song, Elena E. Giorgi, Vitaly V. Ganusov, Fangping Cai, Gayathri Athreya, Hyejin Yoon, Oana Carja, Bhavna Hora, Peter Hraber, Ethan Romero-Severson, Chunlai Jiang, Xiaojun Li, Shuyi Wang, Hui Li, Jesus F. Salazar-Gonzalez, Maria G. Salazar, Nilu Goonetilleke, Brandon F. Keele, David C. Montefiori, Myron S. Cohen, George M. Shaw, Beatrice H. Hahn, Andrew J. McMichael, Barton F. Haynes, Bette Korber, Tanmoy Bhattacharya, Feng Gao
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Recombination contributes to HIV evolution in patients, but its identification can be difficult. Here, the authors develop a computational tool called RAPR to track recombination in patients, identify recombination hot spots, and show contribution of
Externí odkaz:
https://doaj.org/article/30d8c57d3c3f40a3b0cc066eb2a1b284
Autor:
Robert Gallo, Hélène Buanec, Valérie Schiavon, Marine Mérandet, Alexandre Howkit, David Bergerat, Fombellida Lopez C, Armand Bensussan, Jean-David Bouaziz, Arsène Burny, Gilles Darcis, HONGSHUO SONG, Mohammad Sajadi, Shyamasundaran Kottilil, Daniel Zagury
Advances in HIV therapy came from understanding its replication. Further progress toward “functional cure” - no therapy needed as found in Elite Controllers (EC) - may come from insights in pathogenesis and avoidance by EC. Here we show that all
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0615e4dcd3418269d93c1a65cd09af33
https://doi.org/10.21203/rs.3.rs-2813601/v1
https://doi.org/10.21203/rs.3.rs-2813601/v1
Autor:
Robert Gallo, Hélène Buanec, Valérie Schiavon, Marine Mérandet, Alexandre Howkit, HONGSHUO SONG, David Bergerat, Fombellida Lopez C, Armand Bensussan, Jean-David Bouaziz, Arsène Burny, Gilles Darcis, Mohammad Sajadi, Shyamasundaran Kottilil, Daniel Zagury
Like EC, we find that ART-treated patients control serum IFNα concentration and show few immune cell alterations enabling a healthy but fragile medical status. However, treatment interruption leads to elevated IFNα reflecting virus production indic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8cc4d0be47db7fabde4d4c8262fe759b
https://doi.org/10.21203/rs.3.rs-2813616/v1
https://doi.org/10.21203/rs.3.rs-2813616/v1
Publikováno v:
Virology
The ability of HIV-1 to evade neutralizing antibodies (NAbs) in vivo is well demonstrated, but the impact of NAb escape mutations on HIV-1 phenotype other than immune escape itself has rarely been studied. Here, we show that immune escape mutations s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f44245ae21b355f4d72dfe2ea6547541
https://doi.org/10.1016/j.virol.2022.01.010
https://doi.org/10.1016/j.virol.2022.01.010
Autor:
Sodsai Tovanabutra, Rujipas Sirijatuphat, Phuc T. Pham, Lydia Bonar, Elizabeth A. Harbolick, Meera Bose, Hongshuo Song, David Chang, Celina Oropeza, Anne Marie O’Sullivan, Joyce Balinang, Eugene Kroon, Donn J. Colby, Carlo Sacdalan, Joanna Hellmuth, Phillip Chan, Peeriya Prueksakaew, Suteeraporn Pinyakorn, Linda L. Jagodzinski, Duanghathai Sutthichom, Suwanna Pattamaswin, Mark de Souza, Robert A. Gramzinski, Jerome H. Kim, Nelson L. Michael, Merlin L. Robb, Nittaya Phanuphak, Jintanat Ananworanich, Victor Valcour, Gustavo H. Kijak, Eric Sanders-Buell, Serena Spudich, The MHRP Viral Sequencing Core, the RV254/SEARCH 010 Study Team
Publikováno v:
Cells, Vol 8, Iss 8, p 902 (2019)
HIV-1 disseminates to a broad range of tissue compartments during acute HIV-1 infection (AHI). The central nervous system (CNS) can serve as an early and persistent site of viral replication, which poses a potential challenge for HIV-1 remission stra
Externí odkaz:
https://doaj.org/article/549d53bc2b784aa48b5bc7932b75bcd8
Autor:
Hung V. Trinh, Neelakshi Gohain, Peter T. Pham, Christopher Hamlin, Hongshuo Song, Eric Sanders-Buell, Meera Bose, Leigh A. Eller, Swati Jain, Gherman Uritskiy, Venigalla B. Rao, Sodsai Tovanabutra, Nelson L. Michael, Merlin L. Robb, M. Gordon Joyce, Mangala Rao
Publikováno v:
Cells, Vol 8, Iss 6, p 554 (2019)
In the original version of our article [...]
Externí odkaz:
https://doaj.org/article/94e3870ab51f4cbc928543227c87f75b
Autor:
Hung V. Trinh, Neelakshi Gohain, Peter T. Pham, Christopher Hamlin, Hongshuo Song, Eric Sanders-Buell, Meera Bose, Leigh A. Eller, Sodsai Tovanabutra, Nelson L. Michael, Merlin L. Robb, M. Gordon Joyce, Mangala Rao
Publikováno v:
Cells, Vol 8, Iss 4, p 365 (2019)
Reduced risk of HIV-1 infection correlated with antibody responses to the envelope variable 1 and 2 regions in the RV144 vaccine trial. To understand the relationship between antibody responses, V2 sequence, and structure, plasma samples (n = 16) fro
Externí odkaz:
https://doaj.org/article/99114c81eb6442ff9fb11fb3161ebb94