Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Hongshuang Qin"'
Autor:
Hongshuang Qin, Yanxiang Guo
Publikováno v:
ACS omega. 7(34)
Salinomycin exhibits significant systemic adverse reactions such as tachycardia and myoglobinuria in mammals, which hinders its application as a drug for human cancers. Although many strategies aimed at increasing salinomycin's toxicity to cancer cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::776dad88eee290a9c21d984765a83107
https://pubmed.ncbi.nlm.nih.gov/36061682
https://pubmed.ncbi.nlm.nih.gov/36061682
Autor:
Xiaogang Qu, Yuhuan Sun, Hongshuang Qin, Jinsong Ren, Chuanqi Zhao, Jingsheng Niu, Tingting Cui
Publikováno v:
Nucleic Acids Research
Telomeric DNA, whose length homeostasis is closely correlated with immortality of cancer cells, is regarded as a molecular clock for cellular lifespan. Regarding the capacity in forming G-quadruplex, G-rich 3′-overhang (G-overhang) has been conside
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08d99c0745a19f6e0e3c6c3dfbedd1c9
https://doi.org/10.1093/nar/gkaa693
https://doi.org/10.1093/nar/gkaa693
Publikováno v:
Angewandte Chemie International Edition. 61
Even a well-designed system can only control stem cell adhesion, release, and differentiation, while other cell manipulations such as in situ labeling and retention in target tissues, are difficult to achieve in the same system. Herein, native ligand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::296bff87dace4013c073bc31c0975600
https://doi.org/10.1002/anie.202113103
https://doi.org/10.1002/anie.202113103
Publikováno v:
Nano letters. 21(17)
Cancer stem cells (CSCs) play crucial roles in tumor initiation. Amyloid β (Aβ), which is associated with Alzheimer's disease (AD), has been identified to induce cytotoxicity in tumor cells besides brain cells. Herein, we find that oligomeric Aβ1-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a376044a67d46fdbead1964bad3743d6
https://pubmed.ncbi.nlm.nih.gov/34436904
https://pubmed.ncbi.nlm.nih.gov/34436904
Autor:
Chaoqun Liu, Huan Wang, Jinsong Ren, Lihua Kang, Hao Qiu, Xiaogang Qu, Zhaowei Chen, Hongshuang Qin
Publikováno v:
Journal of materials chemistry. B. 6(47)
Photodynamic therapy (PDT) has been widely used as a noninvasive and moderate technique in precision cancer therapy by destroying cancer cells via light-induced reactive oxygen species (ROS). However, the overproduction of heat shock protein 70 (HSP7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66a592349bc75a2d8066c09da297354a
https://pubmed.ncbi.nlm.nih.gov/32255036
https://pubmed.ncbi.nlm.nih.gov/32255036
Publikováno v:
Angewandte Chemie. 130:11352-11357
The effective guidance of mesenchymal stem cell (MSC) differentiation on a substrate by near-infrared (NIR) light is particularly attractive for tissue engineering and regenerative medicine. However, most of current substrates cannot control multidir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::305129860fcefd7569e1f076a3f7e54e
https://doi.org/10.1002/ange.201803939
https://doi.org/10.1002/ange.201803939
Publikováno v:
Chemistry - A European Journal. 23:11226-11229
Telomerase is a key regulator in cell metabolism, tissue renewal, and organismal lifespan. Here we develop a simple strategy to modulate cellular telomerase activity, and further control cell fate based on Mg2+ - and Zn2+ -activated DNAzymes in livin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f324b1f8b27f202786f1876b5602006
https://doi.org/10.1002/chem.201702236
https://doi.org/10.1002/chem.201702236
Publikováno v:
Small (Weinheim an der Bergstrasse, Germany). 15(42)
Nanodrug-based cancer therapy is impeded by poor penetration into deep tumor tissues mainly due to the overexpression of hyaluronic acid (HA) in the tumor extracellular matrix (ECM). Although modification of nanoparticles (NPs) with hyaluronidase (HA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad76a90d9b0078935a5234c32086fc1a
https://pubmed.ncbi.nlm.nih.gov/31468717
https://pubmed.ncbi.nlm.nih.gov/31468717
Autor:
Zhenbo Song, Yongli Bao, Yuxin Li, Jiawei Li, Lihua Zheng, Luguo Sun, Chunxue Niu, Huihan Ai, Hongshuang Qin
Publikováno v:
Biochemical Pharmacology. 177:113984
Pluripotent stem cells are have therapeutic applications in regenerative medicine and drug discovery. However, the differentiation of stem cells in vitro hinders their large-scale production and clinical applications. The maintenance of cell pluripot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73f34b15ec2cdf41fd0c6e6224a0e41c
https://doi.org/10.1016/j.bcp.2020.113984
https://doi.org/10.1016/j.bcp.2020.113984
Publikováno v:
Advanced Therapeutics. 3:1900203
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34360e6e4250465d56551827030301c6
https://doi.org/10.1002/adtp.201900203
https://doi.org/10.1002/adtp.201900203