Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Hongshi Cai"'
Autor:
Hongshi Cai, Jianfeng Liang, Yaoqi Jiang, Ziyi Wang, Hongyu Li, Wenjin Wang, Cheng Wang, Jinsong Hou
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-22 (2024)
Abstract Background Head and neck squamous carcinoma (HNSCC) is known for its high aggressiveness and susceptibility to cervical lymph node metastasis, which greatly contributes to its poor prognosis. During tumorigenesis, many types of cancer cells
Externí odkaz:
https://doaj.org/article/6c814693c3774616b4bf6c8602b58ec5
Autor:
Yue Zhu, Yadong Zhang, Yaoqi Jiang, Hongshi Cai, Jianfeng Liang, Hongyu Li, Cheng Wang, Jinsong Hou
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 8, p 4538 (2024)
Cleft palate only (CPO) is one of the most common craniofacial birth defects. Environmental factors can induce cleft palate by affecting epigenetic modifications such as DNA methylation, histone acetylation, and non-coding RNA. However, there are few
Externí odkaz:
https://doaj.org/article/0ecdbb92592047c09a0f7ed5d3037287
Autor:
Ziyi Wang, Hongyu Li, Hongshi Cai, Jianfeng Liang, Yaoqi Jiang, Fan Song, Chen Hou, Jinsong Hou
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 22, p 16339 (2023)
Ferroptosis is a newly established form of regulated cell death characterized by intracellular lipid peroxidation and iron accumulation that may be a promising cancer treatment strategy. However, the function and therapeutic value of ferroptosis in o
Externí odkaz:
https://doaj.org/article/029cb9f2c8a14845a8e1283f00d557f1
Publikováno v:
Cancer Cell International, Vol 21, Iss 1, Pp 1-19 (2021)
Abstract Background Serine hydroxymethyltransferase 2 (SHMT2) is a vital metabolic enzyme in one carbon metabolism catalyzing the conversion of serine to glycine, which has been reported to play a crucial role in the progression of tumors. However, i
Externí odkaz:
https://doaj.org/article/760263bfd63b47aaa5bfefe17d2e2117
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
The strong invasive and metastatic abilities of oral squamous cell carcinoma (OSCC) cells in the early stage are the main reason for its poor prognosis. The early diagnosis and treatment of OSCC may reduce the metastasis rate and improve the survival
Externí odkaz:
https://doaj.org/article/a2b47b3cc6cf415e99e780991ce363ef
Autor:
Fang Wang, Yue Zhu, Hongshi Cai, Jianfeng Liang, Wenjin Wang, Yan Liao, Yadong Zhang, Cheng Wang, Jinsong Hou
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
N6-methyladenosine (m6A) is the most abundant internal mRNA modification in eukaryotes and is related to stability, localization, or translation efficiency in tumorigenesis. Autophagy plays an important role in the occurrence and development of tumou
Externí odkaz:
https://doaj.org/article/d7c55bd7205047558cec9685e836ad39
Publikováno v:
Cancers, Vol 14, Iss 19, p 4657 (2022)
At present, the prognostic value of N6-methyladenosine (m6A)-related enhancer RNAs (eRNAs) for head and neck squamous cell carcinoma (HNSCC) still remains unclear. Our study aims to explore the prognostic value of m6A-related eRNAs in HNSCC patients
Externí odkaz:
https://doaj.org/article/4fa5ff455fff4ff5b37f4a7236649c03
Autor:
Yuehan Wan, Rosalie G. Hoyle, Nan Xie, Wenjin Wang, Hongshi Cai, Ming Zhang, Zhikun Ma, Gan Xiong, Xiuyun Xu, Zhengxian Huang, Xiqiang Liu, Jiong Li, Cheng Wang
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
MiR-21-5p is one of the most common oncogenic miRNAs that is upregulated in many solid cancers by inhibiting its target genes at the posttranscriptional level. However, the upstream regulatory mechanisms of miR-21-5p are still not well documented in
Externí odkaz:
https://doaj.org/article/8a6d4bebf8634fe6be97e03106f362c0
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
BackgroundAutophagy, a highly conserved self-digesting process, has been deeply involved in the development and progression of oral squamous cell carcinoma (OSCC). However, the prognostic value of autophagy-related genes (ARGs) for OSCC still remains
Externí odkaz:
https://doaj.org/article/db828c11db1f4a718e137ea44bec860f
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Aerobic glycolysis is the main pathway for energy metabolism in cancer cells. It provides energy and biosynthetic substances for tumor progression and metastasis by increasing lactate production. Lactate dehydrogenase A (LDHA) promotes glycolysis pro
Externí odkaz:
https://doaj.org/article/8a6a6a4851bd4ed0b6ebb74d48b234c5