Zobrazeno 1 - 10
of 132
pro vyhledávání: '"Hongqiang Cheng"'
Autor:
Mingjing Yan, Junpeng Gao, Ming Lan, Que Wang, Yuan Cao, Yuxuan Zheng, Yao Yang, Wenlin Li, Xiaoxue Yu, Xiuqing Huang, Lin Dou, Bing Liu, Junmeng Liu, Hongqiang Cheng, Kunfu Ouyang, Kun Xu, Shenghui Sun, Jin Liu, Weiqing Tang, Xiyue Zhang, Yong Man, Liang Sun, Jianping Cai, Qing He, Fuchou Tang, Jian Li, Tao Shen
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-17 (2024)
Abstract DEAD-box helicase 17 (DDX17) is a typical member of the DEAD-box family with transcriptional cofactor activity. Although DDX17 is abundantly expressed in the myocardium, its role in heart is not fully understood. We generated cardiomyocyte-s
Externí odkaz:
https://doaj.org/article/6208415d74f94ce6af017835ee972be3
Autor:
Kejing Ying, Wanghao Xin, Yiming Xu, Dandan Lv, Huiqi Zhu, Yeping Li, Wangting Xu, Chao Yan, Yiqing Li, Hongqiang Cheng, Enguo Chen, Guofeng Ma, Xue Zhang, Yuehai Ke
Publikováno v:
Advanced Science, Vol 11, Iss 13, Pp n/a-n/a (2024)
Abstract Tumor‐associated thrombus (TAT) accounts for a high proportion of venous thromboembolism. Traditional thrombolysis and anticoagulation methods are not effective due to various complications and contraindications, which can easily lead to p
Externí odkaz:
https://doaj.org/article/39481c5176ef457f82c637c70fe40dd2
Autor:
Jiaqi Xu, Shihao Li, Wei Jin, Hui Zhou, Tingting Zhong, Xiaoqing Cheng, Yujuan Fu, Peng Xiao, Hongqiang Cheng, Di Wang, Yuehai Ke, Zhinong Jiang, Xue Zhang
Publikováno v:
JCI Insight, Vol 8, Iss 6 (2023)
As a hallmark of inflammatory bowel disease (IBD), elevated intestinal epithelial cell (IEC) death compromises the gut barrier, activating the inflammatory response and triggering more IEC death. However, the precise intracellular machinery that prev
Externí odkaz:
https://doaj.org/article/908195bca16c4603b86d53b06acc34bd
Autor:
Yiqing Li, Hui Zhou, Pan Liu, Dandan Lv, Yichun Shi, Bufu Tang, Jiaqi Xu, Tingting Zhong, Wangting Xu, Jie Zhang, Jianying Zhou, Kejing Ying, Yongchao Zhao, Yi Sun, Zhinong Jiang, Hongqiang Cheng, Xue Zhang, Yuehai Ke
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 4 (2023)
SIPRα on macrophages binds with CD47 to resist proengulfment signals, but how the downstream signal of SIPRα controls tumor-infiltrating macrophages (TIMs) is still poorly clarified. Here, we report that the CD47/signal regulatory protein α (SIRP
Externí odkaz:
https://doaj.org/article/f08a8fef6ecb46ba8d8c45c6d96c3893
Autor:
Yuxian Guo, Yaru Liu, Shihao Zhao, Wangting Xu, Yiqing Li, Pengwei Zhao, Di Wang, Hongqiang Cheng, Yuehai Ke, Xue Zhang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Redox-dependent regulation plays a key role in the pathogenesis of acute lung injury, but its mechanism is unclear. Here the authors show Grx1-regulated S-glutathionylation of FABP5 controls macrophage inflammation and alleviates acute lung injury.
Externí odkaz:
https://doaj.org/article/ebbe3abc049942979ec819a2aab48259
Autor:
Zhiyong Xu, Chunyi Guo, Qiaoli Ye, Yueli Shi, Yihui Sun, Jie Zhang, Jiaqi Huang, Yizhou Huang, Chunlai Zeng, Xue Zhang, Yuehai Ke, Hongqiang Cheng
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
SHP2 regulates pro-angiogenic VEGF-VEGFR signalling, but its role in tumour angiogenesis is unclear. Here the authors show that endothelial cell-specific deletion of SHP2 impairs tumour growth and angiogenesis in syngeneic mouse models through ASK1-c
Externí odkaz:
https://doaj.org/article/3b558ae5e336405a9be16f4647d6437b
Autor:
Yiqin Cui, Yijie Feng, Yu Xia, Xingpeng Fu, Ming Gong, Jingjing Qian, Jin Yu, Jingjing Ye, Feng Gao, Hongqiang Cheng, Shanshan Mao
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Externí odkaz:
https://doaj.org/article/6187b90f97d9489aa5b9a876cd457b7b
Autor:
Yiqin Cui, Yijie Feng, Yu Xia, Xingpeng Fu, Ming Gong, Jingjing Qian, Jin Yu, Jingjing Ye, Feng Gao, Hongqiang Cheng, Shanshan Mao
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
BackgroundPatients with spinal muscular atrophy (SMA) may suffer from multisystem injury, including an impaired cardiovascular system. However, M-mode echocardiography, the current dominant echocardiographic modality, is limited in the detection of m
Externí odkaz:
https://doaj.org/article/3bf49a039257405b855403ddde82e8e1
Autor:
Pan Liu, Yiqing Li, Mengyao Li, Hui Zhou, Huilun Zhang, Yuefei Zhang, Jiaqi Xu, Yun Xu, Jie Zhang, Bing Xia, Hongqiang Cheng, Yuehai Ke, Xue Zhang
Publikováno v:
iScience, Vol 25, Iss 3, Pp 103867- (2022)
Summary: Radiation-induced lung injury is a common late side effect of thoracic radiotherapy. Endothelial dysfunction following leukocytes infiltration is a prominent feature in this process. Here, we established a clinical-mimicking mouse model of r
Externí odkaz:
https://doaj.org/article/2575cd9c02b74941ad4e162a9d1c65fa
Autor:
Jialan Lv, Zhicheng Pan, Jian Chen, Rui Xu, Dongfei Wang, Jiaqi Huang, Yang Dong, Jing Jiang, Xiang Yin, Hongqiang Cheng, Xiaogang Guo
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Background: Dilated cardiomyopathy (DCM) is a major cause of heart failure worldwide. The Z-line protein Cypher/Z-band alternatively spliced PDZ-motif protein (ZASP) is closely associated with DCM, both clinically and in animal models. Our earlier wo
Externí odkaz:
https://doaj.org/article/c607ad3774cd41b2bad3f2073af6a543