Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Hongna Pan"'
Autor:
Dechun Feng, Xiaogang Xiang, Yukun Guan, Adrien Guillot, Hongkun Lu, Chingwen Chang, Yong He, Hua Wang, Hongna Pan, Cynthia Ju, Sean P. Colgan, Frank Tacke, Xin Wei Wang, George Kunos, Bin Gao
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 15 (2023)
The liver can fully regenerate after partial resection, and its underlying mechanisms have been extensively studied. The liver can also rapidly regenerate after injury, with most studies focusing on hepatocyte proliferation; however, how hepatic necr
Externí odkaz:
https://doaj.org/article/b817fe8712ed41afa48bd7d174477552
Autor:
Yan Guo, Alison.A. Chomiak, Ye Hong, Clara C. Lowe, Caroline A. Kopsidas, Wen-Ching Chan, Jorge Andrade, Hongna Pan, Xiaoming Zhou, Edwin S. Monuki, Yuanyi Feng
Publikováno v:
iScience, Vol 25, Iss 7, Pp 104519- (2022)
Summary: Aging is an intricate process characterized by multiple hallmarks including stem cell exhaustion, genome instability, epigenome alteration, impaired proteostasis, and cellular senescence. Whereas each of these traits is detrimental at the ce
Externí odkaz:
https://doaj.org/article/600df9637a5a4198b6f7f28e33a479b5
Autor:
Alison A. Chomiak, Yan Guo, Caroline A. Kopsidas, Dennis P. McDaniel, Clara C. Lowe, Hongna Pan, Xiaoming Zhou, Qiong Zhou, Martin L. Doughty, Yuanyi Feng
Publikováno v:
iScience, Vol 25, Iss 6, Pp 104354- (2022)
Summary: The NDE1 gene encodes a scaffold protein essential for brain development. Although biallelic NDE1 loss of function (LOF) causes microcephaly with profound mental retardation, NDE1 missense mutations and copy number variations are associated
Externí odkaz:
https://doaj.org/article/241d88fc941543558b66597fdeea1857
Publikováno v:
Molecules, Vol 20, Iss 11, Pp 20355-20380 (2015)
α-Linolenic acid (ALA) is a nutraceutical found in vegetable products such as flax and walnuts. The pleiotropic properties of ALA target endogenous neuroprotective and neurorestorative pathways in brain and involve the transcription factor nuclear f
Externí odkaz:
https://doaj.org/article/046be356651c4e1ab28adcbe046e80c0
Autor:
Jun Chen, Hongna Pan, Cynthia Chen, Wei Wu, Kevin Iskandar, Jeffrey He, Tetsade Piermartiri, David M Jacobowitz, Qian-Sheng Yu, John H McDonough, Nigel H Greig, Ann M Marini
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e99818 (2014)
Organophosphorus (OP) nerve agents are deadly chemical weapons that pose an alarming threat to military and civilian populations. The irreversible inhibition of the critical cholinergic degradative enzyme acetylcholinesterase (AChE) by OP nerve agent
Externí odkaz:
https://doaj.org/article/f1f566335cc54844a09602afaeb064ba
Autor:
Jun Chen, Hongna Pan, Robert H. Lipsky, Anabel Pérez-Gómez, David Cabrera-Garcia, Maria Teresa Fernández-Sánchez, Antonello Novelli, Ann M. Marini
Publikováno v:
Dose-Response, Vol 9 (2011)
Synaptic function is critical for the brain to process experiences dictated by the environment requiring change over the lifetime of the organism. Experience-driven adaptation requires that receptors, signal transduction pathways, transcription and t
Externí odkaz:
https://doaj.org/article/ee5ed92d17104532bf722ad3cc4bad3b
Autor:
Yaojie Fu, Mackowiak, Bryan, Dechun Feng, Hongkun Lu, Yukun Guan, Lehner, Taylor, Hongna Pan, Xin Wei Wang, Yong He, Bin Gao
Publikováno v:
Gut; Oct2023, Vol. 72 Issue 10, p1942-1958, 17p
Publikováno v:
Experimental Biology and Medicine. :153537022311650
Hyperexcitability is a major mechanism implicated in several neuropsychiatric disorders, such as organophosphate-induced status epilepticus (SE), primary epilepsy, stroke, spinal cord injury, traumatic brain injury, schizophrenia, and autism spectrum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4681170a74466fcbc8b8577e0e118d4
https://doi.org/10.1177/15353702231165010
https://doi.org/10.1177/15353702231165010
Autor:
Diego Iacono, Daniel P. Perl, Fabio Leonessa, Steven Parks, Hongna Pan, Erin K Murphy, Jamie B Grimes, Sorana Raiciulescu
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports
Scientific Reports
Traumatic brain injury generated by blast may induce long-term neurological and psychiatric sequelae. We aimed to identify molecular, histopathological, and behavioral changes in rats 2 weeks after explosive-driven double-blast exposure. Rats receive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::186266f162f77ccf64be7b78c59f6c57
http://link.springer.com/article/10.1038/s41598-020-74296-2
http://link.springer.com/article/10.1038/s41598-020-74296-2
Autor:
Shalini Jaiswal, Hongna Pan, Bernard J. Dardzinski, Andrew K. Knutsen, Kimberly R. Byrnes, Nicole Hockenbury
Publikováno v:
NeuroImage. 188:419-426
Traumatic Brain Injury (TBI) affects approximately 2.5 million people in the United States, of which 80% are considered to be mild (mTBI). Previous studies have shown that cerebral glucose uptake and metabolism are altered after brain trauma and func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da913fac03120f32782de526dbb3ef1c
https://doi.org/10.1016/j.neuroimage.2018.12.033
https://doi.org/10.1016/j.neuroimage.2018.12.033