Zobrazeno 1 - 10
of 370
pro vyhledávání: '"Hongming Chen"'
Autor:
Jianle Lao, Yanmin Pang, Hongming Chen, Xiqiang Tang, Rizhu Li, Danlei Tong, Ping Qiu, Qianli Tang
Publikováno v:
The Turkish Journal of Gastroenterology, Vol 35, Iss 9, Pp 699-708 (2024)
Background/Aims: Esophageal cancer (ESCA) is a high-incidence disease worldwide, of which the 5-year survival rate remains dismal since the cellular basis of ESCA remains largely unclear. Herein, we attempted to examine the manifestation of fucosyltr
Externí odkaz:
https://doaj.org/article/795a1ccc0fe2401183b91defdecc7136
Autor:
Zhangming Niu, Xianglu Xiao, Wenfan Wu, Qiwei Cai, Yinghui Jiang, Wangzhen Jin, Minhao Wang, Guojian Yang, Lingkang Kong, Xurui Jin, Guang Yang, Hongming Chen
Publikováno v:
Scientific Data, Vol 11, Iss 1, Pp 1-15 (2024)
Abstract Accurately predicting ADMET (Absorption, Distribution, Metabolism, Excretion, and Toxicity) properties early in drug development is essential for selecting compounds with optimal pharmacokinetics and minimal toxicity. Existing ADMET-related
Externí odkaz:
https://doaj.org/article/4e067a8038d445578f77cf5d1cdc40e2
Publikováno v:
Journal of Cheminformatics, Vol 16, Iss 1, Pp 1-15 (2024)
Abstract Despite recent advancement in 3D molecule conformation generation driven by diffusion models, its high computational cost in iterative diffusion/denoising process limits its application. Here, an equivariant consistency model (EC-Conf) was p
Externí odkaz:
https://doaj.org/article/57bbd00555b9414d9b1a942e5d7a9036
Publikováno v:
BMC Pediatrics, Vol 24, Iss 1, Pp 1-7 (2024)
Abstract Background Retinopathy of prematurity (ROP) is a common disease in premature infants. In recent years, most researchers have used lactic acid as poor prognosis marker in premature infants. This study aims to explore investigate the impact of
Externí odkaz:
https://doaj.org/article/4fbdce3634014f5a8ea8b7d0a33275d0
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
IntroductionIn recent years, the use of EEG signals for seizure detection has gained widespread academic attention. Aiming at the problem of overfitting deep learning models due to the small number of EEG signal data during epilepsy detection, this p
Externí odkaz:
https://doaj.org/article/8f86d2a70ca84bddb1b63f5c6e017667
Autor:
Baiqing Li, Shimin Su, Chan Zhu, Jie Lin, Xinyue Hu, Lebin Su, Zhunzhun Yu, Kuangbiao Liao, Hongming Chen
Publikováno v:
Journal of Cheminformatics, Vol 15, Iss 1, Pp 1-12 (2023)
Abstract In recent years, it has been seen that artificial intelligence (AI) starts to bring revolutionary changes to chemical synthesis. However, the lack of suitable ways of representing chemical reactions and the scarceness of reaction data has li
Externí odkaz:
https://doaj.org/article/c17156337f624270b7ae21f9d05248bd
Autor:
Xiaodan Yin, Chang-Yu Hsieh, Xiaorui Wang, Zhenxing Wu, Qing Ye, Honglei Bao, Yafeng Deng, Hongming Chen, Pei Luo, Huanxiang Liu, Tingjun Hou, Xiaojun Yao
Publikováno v:
Research, Vol 7 (2024)
Deep learning (DL)-driven efficient synthesis planning may profoundly transform the paradigm for designing novel pharmaceuticals and materials. However, the progress of many DL-assisted synthesis planning (DASP) algorithms has suffered from the lack
Externí odkaz:
https://doaj.org/article/48a7714075234799af6f43cd8b3ba619
Publikováno v:
Artificial Intelligence in the Life Sciences, Vol 3, Iss , Pp 100065- (2023)
Ligand-based virtual screening plays an important role for cases in which protein structures are not available. Among ligand-based methods, accurate and fast prediction of protein-ligand binding affinity is crucial for reducing computational cost and
Externí odkaz:
https://doaj.org/article/1a0027bfba174703be2c1d963e38ae66
Publikováno v:
Artificial Intelligence in the Life Sciences, Vol 3, Iss , Pp 100058- (2023)
The A2A adenosine receptor (A2AR) is emerging as a promising drug target for cancer immunotherapy. Novel A2AR antagonists are highly demanded due to few candidates entering clinic trials specific for cancer treatment. Structure-based virtual screenin
Externí odkaz:
https://doaj.org/article/831093c9171d4b5ead261f3587cbbf56
Publikováno v:
Metals, Vol 14, Iss 3, p 351 (2024)
As an important component that affects the storage performance of sodium-ion batteries (SIBs), novel anode materials still need to be well explored. Herein, CoS1.097@C core–shell fibers as anode material were designed via coaxial electrospinning, s
Externí odkaz:
https://doaj.org/article/92efefc1b8a14027bbfa89a9811939b8