A whole-mount immunohistochemistry protocol for detection of mouse corneal nerves

Autor: Hongmin Yun, Kira L. Lathrop, Anthony J. St. Leger

Publikováno v: STAR Protocols, Vol 2, Iss 3, Pp 100734- (2021)

Summary: A cornea is innervated by sensory nerves, which branch into thick trunks, subbasal plexuses, and sensory endings. Appropriate assessment of nerve structure in a tissue provides a more complete understanding of the role of nerves in health an

Externí odkaz: https://doaj.org/article/95818de75a4d4cdeb99f0bda74665974

Author Correction: Human stem cells home to and repair laser-damaged trabecular meshwork in a mouse model

Autor: Hongmin Yun, Yiwen Wang, Yi Zhou, Ajay Kumar, Ke Wang, Ming Sun, Donna B. Stolz, Xiaobo Xia, C. Ross Ethier, Yiqin Du

Publikováno v: Communications Biology, Vol 4, Iss 1, Pp 1-1 (2021)

A Correction to this paper has been published: https://doi.org/10.1038/s42003-021-01957-x

Externí odkaz: https://doaj.org/article/3961cb752cb24615861137c1a98e878d

Sensory Nerve Retraction and Sympathetic Nerve Innervation Contribute to Immunopathology of Murine Recurrent Herpes Stromal Keratitis

Autor: Hongmin Yun, Xiao-Tang Yin, Patrick M. Stuart, Anthony J. St. Leger

Publikováno v: Investigative ophthalmologyvisual science. 63(2)

Herpes stromal keratitis (HSK) represents a spectrum of pathologies which is caused by herpes simplex virus type 1 (HSV-1) infection and is considered a leading cause of infectious blindness. HSV-1 infects corneal sensory nerves and establishes laten

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9851bf06433948d0a03b257f3d08f3a
https://pubmed.ncbi.nlm.nih.gov/35103749

Regenerative therapy for the Cornea

Autor: Martha L. Funderburgh, Ajay Kumar, Yiqin Du, Hongmin Yun

Publikováno v: Prog Retin Eye Res

The cornea is the outmost layer of the eye, unique in its transparency and strength. The cornea not only transmits the light essential for vision, also refracts light, giving focus to images. Each of the three layers of the cornea has properties esse

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb00ca7ccf9082e0742668ef85c119b9
https://doi.org/10.1016/j.preteyeres.2021.101011

Consensus Recommendation for Mouse Models of Ocular Hypertension to Study Aqueous Humor Outflow and Its Mechanisms

Autor: Colleen M. McDowell, Krishnakumar Kizhatil, Michael H. Elliott, Darryl R. Overby, Joseph van Batenburg-Sherwood, J. Cameron Millar, Markus H. Kuehn, Gulab Zode, Ted S. Acott, Michael G. Anderson, Sanjoy K. Bhattacharya, Jacques A. Bertrand, Terete Borras, Diane E. Bovenkamp, Lin Cheng, John Danias, Michael Lucio De Ieso, Yiqin Du, Jennifer A. Faralli, Rudolf Fuchshofer, Preethi S. Ganapathy, Haiyan Gong, Samuel Herberg, Humberto Hernandez, Peter Humphries, Simon W. M. John, Paul L. Kaufman, Kate E. Keller, Mary J. Kelley, Ruth A. Kelly, David Krizaj, Ajay Kumar, Brian C. Leonard, Raquel L. Lieberman, Paloma Liton, Yutao Liu, Katy C. Liu, Navita N. Lopez, Weiming Mao, Timur Mavlyutov, Fiona McDonnell, Gillian J. McLellan, Philip Mzyk, Andrews Nartey, Louis R. Pasquale, Gaurang C. Patel, Padmanabhan P. Pattabiraman, Donna M. Peters, Vijaykrishna Raghunathan, Ponugoti Vasantha Rao, Naga Rayana, Urmimala Raychaudhuri, Ester Reina-Torres, Ruiyi Ren, Douglas Rhee, Uttio Roy Chowdhury, John R. Samples, E. Griffen Samples, Najam Sharif, Joel S. Schuman, Val C. Sheffield, Cooper H. Stevenson, Avinash Soundararajan, Preeti Subramanian, Chenna Kesavulu Sugali, Yang Sun, Carol B. Toris, Karen Y. Torrejon, Amir Vahabikashi, Janice A. Vranka, Ting Wang, Colin E. Willoughby, Chen Xin, Hongmin Yun, Hao F. Zhang, Michael P. Fautsch, Ernst R. Tamm, Abbot F. Clark, C. Ross Ethier, W. Daniel Stamer

Publikováno v: Investigative ophthalmology & visual science, vol 63, iss 2

Due to their similarities in anatomy, physiology, and pharmacology to humans, mice are a valuable model system to study the generation and mechanisms modulating conventional outflow resistance and thus intraocular pressure. In addition, mouse models

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc2366dca55a396f9cef10de74cc76d5
https://doi.org/10.1167/iovs.63.2.12