Výsledky vyhledávání - "Hongmi Huang"

Akademický článek

Neuroplastin exerts antiepileptic effects through binding to the α1 subunit of GABA type A receptors to inhibit the internalization of the receptors

Autor: Sijun Li, Xing Wei, Hongmi Huang, Lin Ye, Meigang Ma, Lanfeng Sun, Yuling Lu, Yuan Wu

Publikováno v: Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-16 (2023)

Abstract Background Seizures are associated with a decrease in γ-aminobutyric type A acid receptors (GABAaRs) on the neuronal surface, which may be regulated by enhanced internalization of GABAaRs. When interactions between GABAaR subunit α-1 (GABR

Externí odkaz: https://doaj.org/article/8b55ba7abecc47e2b1425f981fb53c18

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The recycling of AMPA receptors/GABAa receptors is related to neuronal excitation/inhibition imbalance and may be regulated by KIF5A

Autor: Sijun Li, Hongmi Huang, Xin Wei, Lin Ye, Meigang Ma, Min Ling, Yuan Wu

Publikováno v: Annals of translational medicine. 10(20)

Excitation/inhibition imbalance (E/I imbalance), which involves an increase of alpha-amino-3-hydroxy-5-methyl-4-isoxazole (AMPA) receptors (AMPARs) and decrease of gamma-aminobutyric acid type A (GABA) type A receptors (GABAaRs) on the neuron surface

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0458a82f8c4aa6279e2ae1bd5535783
https://pubmed.ncbi.nlm.nih.gov/36388788

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Neuroplastin Exerts Antiepileptic Effects Through Binding to the α 1 Subunit of GABA Type A Receptors to Inhibit the Internalization of the Receptors

Autor: Sijun Li, Xing Wei, Hongmi Huang, Lin Ye, Meigang Ma, Lanfeng Sun, Yuling Lu, Yuan Wu

Publikováno v: SSRN Electronic Journal.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::23b334cfe3d766c621b661aa5d296c67
https://doi.org/10.2139/ssrn.4304745

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Klotho alleviates NLRP3 inflammasome-mediated neuroinflammation in a temporal lobe epilepsy rat model by activating the Nrf2 signaling pathway

Autor: Tao Xiang, Xiaodan Luo, Lin Ye, Hongmi Huang, Yuan Wu

Publikováno v: Epilepsybehavior : EB. 128

Neuroinflammation not only contributes to epileptogenesis and neurodegeneration, but is also associated with cognitive impairment. Nod-like receptor family pyrin domain containing 3 (NLRP3) inflammasome-mediated neuroinflammation is positively correl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::822aad0514b12e2c383056f5d6a6c40a
https://pubmed.ncbi.nlm.nih.gov/35104732

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Identification of significant immune-related genes for epilepsy via bioinformatics analysis

Autor: Yuan Wu, Lin Ye, Yifei Huang, Tao Xiang, Xiaodan Luo, Hongmi Huang

Publikováno v: Ann Transl Med

Background Epilepsy is one of the most common neurological disorders, but its underlying mechanism has remained obscure, and the role of immune-related genes (IRGs) in epilepsy have not yet been investigated. Therefore, in this study, we explored the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b99c2f984d2940a294d8faf145ff440
https://pubmed.ncbi.nlm.nih.gov/34430602

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