Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Hongmei Piao"'
Autor:
Qiaoyun Bai, Ruobai Liu, Changlin Quan, Xue Han, Dandan Wang, Chongyang Wang, Zhiguang Wang, Li Li, Liangchang Li, Hongmei Piao, Yilan Song, Guanghai Yan
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
DEK protein is highly expressed in asthma. However, the mechanism of DEK on mitophagy in asthma has not been fully understood. This study aims to investigate the role and mechanism of DEK in asthmatic airway inflammation and in regulating PINK1-Parki
Externí odkaz:
https://doaj.org/article/ff88ba0ae92144079483dc3b6b9436b7
Autor:
Yilan Song, Jingzhi Jiang, Qiaoyun Bai, Siqi Liu, Yalin Zhang, Chang Xu, Hongmei Piao, Liangchang Li, Guanghai Yan
Publikováno v:
BMC Pulmonary Medicine, Vol 23, Iss 1, Pp 1-13 (2023)
Abstract Background Asthma is characterized by chronic inflammation and airway remodeling. However, limited study is conducted on the gene expression profiles of ovalbumin (OVA) induced asthma in mice. Here, we explored the gene expression profiles i
Externí odkaz:
https://doaj.org/article/fdf02e15961347b694c40da73be0b560
Autor:
Chisato Kamimaki, Nobuaki Kobayashi, Momo Hirata, Kohei Somekawa, Nobuhiko Fukuda, Sousuke Kubo, Seigo Katakura, Shuhei Teranishi, Keisuke Watanabe, Nobuyuki Horita, Yu Hara, Masaki Yamamoto, Makoto Kudo, Hongmei Piao, Takeshi Kaneko
Publikováno v:
Thoracic Cancer, Vol 12, Iss 11, Pp 1726-1734 (2021)
Abstract Background Immune checkpoint inhibitors are a standard treatment for advanced lung cancer, although it remains important to identify biomarkers that can accurately predict treatment response. Immune checkpoint inhibitors enhance the antitumo
Externí odkaz:
https://doaj.org/article/d84a8207a6c34ec28c0240f6c21be844
Autor:
Nobuaki Kobayashi, Seigo Katakura, Chisato Kamimaki, Kohei Somekawa, Nobuhiko Fukuda, Katsushi Tanaka, Keisuke Watanabe, Nobuyuki Horita, Yu Hara, Hongmei Piao, Takeshi Kaneko
Publikováno v:
Thoracic Cancer, Vol 12, Iss 7, Pp 1096-1105 (2021)
Abstract Background Differences in the resistance mechanisms of epidermal growth factor receptor tyrosine kinase inhibitors in patients with non‐small cell lung cancer (NSCLC) harboring epidermal growth factor receptor mutations are unknown. This m
Externí odkaz:
https://doaj.org/article/e7d7e3b79e634efbba3ba1366ad38f0a
Autor:
Zhiguang Wang, Yilan Song, Jingzhi Jiang, Yihua Piao, Li Li, Qiaoyun Bai, Chang Xu, Hanye Liu, Liangchang Li, Hongmei Piao, Guanghai Yan
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Bronchial asthma is characterized by chronic airway inflammation, airway hyperresponsiveness, and airway remodeling. MicroRNA (miRNA) has recently been implicated in the pathogenesis of asthma. However, the mechanisms of different miRNAs in asthma ar
Externí odkaz:
https://doaj.org/article/fd17ea0bcbbb4a1ba221df52928b27d1
Autor:
Seigo Katakura, Nobuaki Kobayashi, Hisashi Hashimoto, Chisato Kamimaki, Katsushi Tanaka, Sousuke Kubo, Kentaro Nakashima, Shuhei Teranishi, Saki Manabe, Keisuke Watanabe, Nobuyuki Horita, Yu Hara, Masaki Yamamoto, Makoto Kudo, Hongmei Piao, Takeshi Kaneko
Publikováno v:
Thoracic Cancer, Vol 11, Iss 10, Pp 2975-2982 (2020)
Background Advanced non‐small cell lung cancer (NSCLC) has a high mortality rate and poor prognosis. However, outcomes have gradually improved after the introduction of novel immunotherapies, including immune checkpoint inhibitors (ICIs). Although
Externí odkaz:
https://doaj.org/article/16617066622c41d597b7c6fc08914603
Autor:
Nobuaki Kobayashi, Hisashi Hashimoto, Chisato Kamimaki, Ryo Nagasawa, Katsushi Tanaka, Sousuke Kubo, Seigo Katakura, Hao Chen, Nobuyuki Hirama, Ryota Ushio, Ayako Aoki, Kentaro Nakashima, Shuhei Teranishi, Saki Manabe, Hiroki Watanabe, Nobuyuki Horita, Keisuke Watanabe, Yu Hara, Masaki Yamamoto, Makoto Kudo, Hongmei Piao, Takeshi Kaneko
Publikováno v:
Thoracic Cancer, Vol 11, Iss 8, Pp 2125-2129 (2020)
Introduction As most patients with epidermal growth factor receptor (EGFR)‐mutant non‐small cell lung cancer (NSCLC) develop progressive disease after treatment with osimertinib, it is important to develop more effective treatment options. Afatin
Externí odkaz:
https://doaj.org/article/087b6fea136f41399c90d1366b3a7289
Autor:
Shuhei Teranishi, Nobuaki Kobayashi, Seigo Katakura, Chisato Kamimaki, Sousuke Kubo, Yuji Shibata, Masaki Yamamoto, Makoto Kudo, Hongmei Piao, Takeshi Kaneko
Publikováno v:
Thoracic Cancer, Vol 11, Iss 4, Pp 983-992 (2020)
Abstract Background Currently, anticancer immunotherapy based on PD‐1/PD‐L1 blockade with immune checkpoint inhibitors (ICIs) is being used as a standard therapy for non‐small cell lung cancer (NSCLC). However, more effective treatments are req
Externí odkaz:
https://doaj.org/article/1185b879a4494c47b0ae9cf2c5d739ab
Autor:
Zhiguang Wang, Liangchang Li, Chongyang Wang, Yihua Piao, Jingzhi Jiang, Li Li, Guanghai Yan, Hongmei Piao
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
This article aims to investigate the effects of recombinant pyrin domain (RPYD) on airway inflammation and remodeling in mice with chronic asthma. The chronic asthma BALB/c mouse model was first sensitized by ovalbumin (OVA) and then challenged by OV
Externí odkaz:
https://doaj.org/article/412f34852d634f9da8fbcb2af33b6f77
Autor:
Chongyang Wang, Mingyu Zheng, Yunho Choi, Jingzhi Jiang, Li Li, Junfeng Li, Chang Xu, Zhemin Xian, Yan Li, Hongmei Piao, Liangchang Li, Guanghai Yan
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
The study is to investigate the effect of cryptotanshinone (CTS) on airway remodeling and the possible mechanism. Male BALB/c mice were pretreated with CTS or dexamethasone 30 min before nebulized inhalation of ovalbumin (OVA). CTS significantly inhi
Externí odkaz:
https://doaj.org/article/cae7a8f4717646e18acac41304b78513