Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Hongmao, Sun"'
Autor:
Dorjbal Dorjsuren, Richard T. Eastman, Kathryn J. Wicht, Daniel Jansen, Daniel C. Talley, Benjamin A. Sigmon, Alexey V. Zakharov, Norma Roncal, Andrew T. Girvin, Yevgeniya Antonova-Koch, Paul M. Will, Pranav Shah, Hongmao Sun, Carleen Klumpp-Thomas, Sachel Mok, Tomas Yeo, Stephan Meister, Juan Jose Marugan, Leila S. Ross, Xin Xu, David J. Maloney, Ajit Jadhav, Bryan T. Mott, Richard J. Sciotti, Elizabeth A. Winzeler, Norman C. Waters, Robert F. Campbell, Wenwei Huang, Anton Simeonov, David A. Fidock
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract The spread of Plasmodium falciparum parasites resistant to most first-line antimalarials creates an imperative to enrich the drug discovery pipeline, preferably with curative compounds that can also act prophylactically. We report a phenotyp
Externí odkaz:
https://doaj.org/article/3166e3dd3b5945e88b4f3c4eb22c8065
Autor:
Eric Cheng, Dorjbal Dorjsuren, Stephanie Lehman, Charles L. Larson, Steven A. Titus, Hongmao Sun, Alexey Zakharov, Ganesha Rai, Robert A. Heinzen, Anton Simeonov, Matthias P. Machner
Publikováno v:
mBio, Vol 13, Iss 2 (2022)
ABSTRACT Bacterial type IV secretion systems (T4SSs) are macromolecular machines that translocate effector proteins across multiple membranes into infected host cells. Loss of function mutations in genes encoding protein components of the T4SS render
Externí odkaz:
https://doaj.org/article/17ea4c8ef25440e6a85c917d59465e91
Autor:
Victor Clausse, Yuhong Fang, Dingyin Tao, Harichandra D. Tagad, Hongmao Sun, Yuhong Wang, Surendra Karavadhi, Kelly Lane, Zhen-Dan Shi, Olga Vasalatiy, Christopher A. LeClair, Rebecca Eells, Min Shen, Samarjit Patnaik, Ettore Appella, Nathan P. Coussens, Matthew D. Hall, Daniel H. Appella
Publikováno v:
ACS Pharmacology & Translational Science. 5:993-1006
Wild-type P53-induced phosphatase 1 (WIP1), also known as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a77d015aae85ddd0ddd8d9d272ae29f
https://doi.org/10.1021/acsptsci.2c00147
https://doi.org/10.1021/acsptsci.2c00147
Autor:
Anup P. Challa, Xin Hu, Ya-Qin Zhang, Jeffrey Hymes, Bret D. Wallace, Surendra Karavadhi, Hongmao Sun, Samarjit Patnaik, Matthew D. Hall, Min Shen
Publikováno v:
J Chem Inf Model
Despite the potency of most first-line anti-cancer drugs, non-adherence to these drug regimens remains high and is attributable to the prevalence of “off-target” drug effects that result in serious adverse events (SAEs) like hair loss, nausea, vo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f1eb78c4aab121875378e120b648365
https://doi.org/10.1021/acs.jcim.1c01414
https://doi.org/10.1021/acs.jcim.1c01414
Autor:
Natalia J Martinez, Ganesha Rai, Adam Yasgar, Wendy A Lea, Hongmao Sun, Yuhong Wang, Diane K Luci, Shyh-Ming Yang, Kana Nishihara, Shunichi Takeda, Mohiuddin Sagor, Irina Earnshaw, Tetsuya Okada, Kazutoshi Mori, Kelli Wilson, Gregory J Riggins, Menghang Xia, Maurizio Grimaldi, Ajit Jadhav, David J Maloney, Anton Simeonov
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0161486 (2016)
The endoplasmic reticulum (ER) is involved in Ca2+ signaling and protein folding. ER Ca2+ depletion and accumulation of unfolded proteins activate the molecular chaperone GRP78 (glucose-regulated protein 78) which in turn triggers the ER stress respo
Externí odkaz:
https://doaj.org/article/32648e68d1c64d85b6cf13c0dd1ec1af
Autor:
Natalia J Martinez, Ganesha Rai, Adam Yasgar, Wendy A Lea, Hongmao Sun, Yuhong Wang, Diane K Luci, Shyh-Ming Yang, Kana Nishihara, Shunichi Takeda, Mohiuddin, Irina Earnshaw, Tetsuya Okada, Kazutoshi Mori, Kelli Wilson, Gregory J Riggins, Menghang Xia, Maurizio Grimaldi, Ajit Jadhav, David J Maloney, Anton Simeonov
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0166506 (2016)
[This corrects the article DOI: 10.1371/journal.pone.0161486.].
Externí odkaz:
https://doaj.org/article/e1507d1cbf0448b0bcd91c7fd014f013
Autor:
Hongmao Sun, Nathan P. Coussens, Carina Danchik, Leah M. Wachsmuth, Mark J. Henderson, Samarjit Patnaik, Matthew D. Hall, Ashley L. Molinaro, Dayle A. Daines, Min Shen
Publikováno v:
J Chem Inf Model
Nontypeable Haemophilus influenzae (NTHi) are clinically important Gram-negative bacteria that are responsible for various human mucosal diseases, including otitis media (OM). Recurrent OM caused by NTHi is common and infections which recur less than
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::602865876fdcb82773a26ed04f1aa774
https://europepmc.org/articles/PMC10041999/
https://europepmc.org/articles/PMC10041999/
Autor:
Pietro Mancuso, Rossella Tricarico, Vikram Bhattacharjee, Laura Cosentino, Yuwaraj Kadariya, Jaroslav Jelinek, Emmanuelle Nicolas, Margret Einarson, Neil Beeharry, Karthik Devarajan, Richard A. Katz, Dorjbal G. Dorjsuren, Hongmao Sun, Anton Simeonov, Antonio Giordano, Joseph R. Testa, Guillaume Davidson, Irwin Davidson, Lionel Larue, Robert W. Sobol, Timothy J. Yen, Alfonso Bellacosa
Publikováno v:
Oncogene. 41:3300-3301
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ececb51a9b84fc5b5a3d876aa2ca5688
https://doi.org/10.1038/s41388-022-02335-5
https://doi.org/10.1038/s41388-022-02335-5
Autor:
Sharlyn J. Mazur, Olga Vasalatiy, Dingyin Tao, Daniel H. Appella, Subrata Debnath, Yuhong Wang, Rebecca Eells, Harichandra D. Tagad, Mark J. Henderson, Victor Clausse, Kelly Lane, Nathan P. Coussens, Christopher A. LeClair, Zhen-Dan Shi, Martin R. Webb, Min Shen, Yuhong Fang, Lynn K. Baker, Matthew D. Hall, Hongmao Sun, Ettore Appella
Publikováno v:
The Journal of Biological Chemistry
Wildtype P53-induced phosphatase 1 (WIP1) is a member of the magnesium-dependent serine/threonine protein phosphatase (PPM) family and is induced by P53 in response to DNA damage. In several human cancers, the WIP1 protein is overexpressed, which is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::195e41fcef7b640fd2b44107385f675a
http://europepmc.org/articles/PMC6873202
http://europepmc.org/articles/PMC6873202