Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Hongkun Bao"'
Autor:
Xingzong Sun, Menghan Qian, Hongliang Li, Lei Wang, Yunjie Zhao, Min Yin, Lili Dai, Hongkun Bao
Publikováno v:
Cell Death and Disease, Vol 14, Iss 11, Pp 1-20 (2023)
Abstract Multiple sclerosis (MS) is an autoimmune and neurodegenerative disease of the central nervous system (CNS) that is characterized by myelin damage, followed by axonal and ultimately neuronal loss, which has been found to be associated with mi
Externí odkaz:
https://doaj.org/article/b9f0fdef47164bafa6f100f98cea6255
Autor:
Dandan Zhang, Yue Jia, Xingzong Sun, Haoran Li, Min Yin, Hongliang Li, Lili Dai, Li Han, Lei Wang, Menghan Qian, Jing Du, Keming Zhu, Hongkun Bao
Publikováno v:
Journal of Immunology Research, Vol 2022 (2022)
Demyelinating diseases such as multiple sclerosis (MS) are chronic inflammatory autoimmune diseases and involve demyelination and axonal degeneration. Microglia rapidly respond to changes in the environment by altering morphotype and function during
Externí odkaz:
https://doaj.org/article/041cfc7144364316b212ee1411258ddd
Autor:
Yangyang Hou, Shaolei Luo, Yaping Zhang, Yue Jia, Haoran Li, Chunjie Xiao, Hongkun Bao, Jing Du
Publikováno v:
Journal of Integrative Neuroscience, Vol 18, Iss 4, Pp 393-400 (2019)
Regulation of neuroinflammation is critical to control the detrimental impact of chronic stress in the central nervous system. Neuroinflammation occurs in response to chronic stress, leading to enhanced neuronal damage in the brain. We investigated t
Externí odkaz:
https://doaj.org/article/e374b9db51e7494c8191aff4fc99b41d
Autor:
Hongkun Bao, Pengzhan Ran, Lijuan Sun, Weihong Hu, Hongliang Li, Chunjie Xiao, Keming Zhu, Jing Du
Publikováno v:
Pharmaceutical Biology, Vol 55, Iss 1, Pp 299-305 (2017)
Context: Griflola frondosa (Fr) S.F. Gray (Meripilaceae) (GF) is a medical mushroom, and its regulation of the immune system is of interest for the treatment of mood disorders. α-Amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) receptors a
Externí odkaz:
https://doaj.org/article/abfc86dc4396424cb388467c5d89180b
Autor:
Haoran Li, Xuequan Zhu, Jinjie Xu, Lei Li, Weijing Kan, Hongkun Bao, Jiyi Xu, Weiwei Wang, Yang Yang, Pei Chen, Yuchuan Zou, Yuan Feng, Jian Yang, Jing Du, Gang Wang
Publikováno v:
International immunopharmacology. 115
Emerging evidence from animal and human studies has suggested that small microbial metabolites generated in the gut influence host mood and behavior. Our previous study reported that patients with major depressive disorder (MDD) reduced the abundance
Publikováno v:
Neurochemical Research
Neuroinflammation plays an important role in the onset and progression of neurodegenerative diseases. Microglia-mediated neuroinflammation have been proved to be the main reason for causing the neurodegenerative diseases. Ganoderic acid A (GAA), isol
Autor:
Shaolei Luo, Bruce S. McEwen, Yangyang Hou, Peixiong Yuan, Yue Jia, Husseini K. Manji, Lei Feng, Yaping Zhang, Richard G. Hunter, Haoran Li, Chunjie Xiao, Hongkun Bao, Gang Wang, Jing Du
Publikováno v:
Journal of Neurochemistry. 158:358-372
Molecular abnormalities within the Glucocorticoid Receptor (GR) stress signaling pathway involved in dysfunction of mitochondria and confer vulnerability to stress related psychiatric disorders. Bcl-2 associated athanogene (Bag-1) is a target for the
Autor:
Yuan Feng, Dandan Zhang, Shaolei Luo, Li Han, Yuhuan Xiao, Chunjie Xiao, Jing Du, Han Wang, Haoran Li, Yue Jia, Yang Yang, Lili Dai, Lei Feng, Gang Wang, Hongkun Bao
Publikováno v:
Biochemical pharmacology. 188
Major depressive disorder (MDD) is a common, chronic, recurrent disease. The existing drugs are ineffective for approximately half of patients, so the development of antidepressant drugs with novel mechanisms is urgent. Cumulative evidence has shown
Publikováno v:
Journal of Biotechnology and Biomedicine.
At present, the novel Covid-19 pneumonia is prevalent, affecting millions of people. Here, we summarized the pharmacological basis of adenosine, adenosine receptors, adenosine agonist cordycepin (3'-deoxyadenosine), and Cordyceps product in the brain
Autor:
Dandan Zhang, Li Han, Yue Jia, Jing Du, Peng Wu, Fu-Chun Zhou, Gang Wang, Chunjie Xiao, Lei Feng, Chuanyue Wang, Yuhuan Xiao, Haoran Li, Hongkun Bao, Haijing Yu, Shaolei Luo
Publikováno v:
Biochemical pharmacology. 185
Multiple sclerosis (MS), as an inflammatory demyelinating disorder of central nervous system, is the leading cause of non-traumatic neurologic disability in young adults. The pathogenesis of MS remains unknown, however, a dysregulation of glia-neuroi