Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Hongkuan Wang"'
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-13 (2021)
Abstract Background Meiosis is a specialized cell division that underpins sexual reproduction in most eukaryotes. During meiosis, interhomolog meiotic recombination facilitates accurate chromosome segregation and generates genetic diversity by shuffl
Externí odkaz:
https://doaj.org/article/fadb2e6495cf4b07aabdd4cf876931ea
Autor:
Chengpeng He, Zhiyu Chen, Yiyong Zhao, Yue Yu, Hongkuan Wang, Cong Wang, Gregory P Copenhaver, Ji Qi, Yingxiang Wang
Publikováno v:
PLoS Genetics, Vol 18, Iss 2, p e1010041 (2022)
Histone methylation and demethylation play important roles in plant growth and development, but the involvement of histone demethylation during meiosis is poorly understood. Here we show that disruption of Arabidopsis thaliana INCREASE IN BONSAI METH
Externí odkaz:
https://doaj.org/article/fce679ee2a0c41bfb8efc670b52fb6ba
Autor:
Hongkuan Wang, Wanyue Xu, Yujin Sun, Qichao Lian, Cong Wang, Chaoyi Yu, Chengpeng He, Jun Wang, Hong Ma, Gregory P Copenhaver, Yingxiang Wang
Publikováno v:
PLoS Genetics, Vol 16, Iss 6, p e1008849 (2020)
Cohesin, a multisubunit protein complex, is required for holding sister chromatids together during mitosis and meiosis. The recruitment of cohesin by the sister chromatid cohesion 2/4 (SCC2/4) complex has been extensively studied in Saccharomyces cer
Externí odkaz:
https://doaj.org/article/b28161f46ab24523a32e1ced5c7d7e5e
Autor:
Jennifer L Modliszewski, Hongkuan Wang, Ashley R Albright, Scott M Lewis, Alexander R Bennett, Jiyue Huang, Hong Ma, Yingxiang Wang, Gregory P Copenhaver
Publikováno v:
PLoS Genetics, Vol 14, Iss 5, p e1007384 (2018)
For most eukaryotes, sexual reproduction is a fundamental process that requires meiosis. In turn, meiosis typically depends on a reciprocal exchange of DNA between each pair of homologous chromosomes, known as a crossover (CO), to ensure proper chrom
Externí odkaz:
https://doaj.org/article/fe71de6b59264d75bf65ed8ea1477a3d
Autor:
Tianyi Wang, Hongkuan Wang, Qichao Lian, Qian Jia, Chenjiang You, Copenhaver, Gregory P., Cong Wang, Yingxiang Wang
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 12/26/2023, Vol. 120 Issue 52, p1-10, 21p
Autor:
Hongkuan Wang, William J. Tucker, Jitendra Jonnagaddala, Aletta E. Schutte, Bin Jalaludin, Siaw-Teng Liaw, Kerry-Anne Rye, Raymond K. Wong, Kwok Leung Ong
Publikováno v:
International Journal of Cardiology.
Publikováno v:
2022 IEEE 9th International Conference on Data Science and Advanced Analytics (DSAA).
Autor:
Ying Qu, Hongkuan Wang
Publikováno v:
2022 International Conference on Computation, Big-Data and Engineering (ICCBE).
Autor:
Yue-zhong Li, Biao Tang, Guoping Zhao, Yucong Yu, Lin Zhang, Hongkuan Wang, Xiaoming Ding, Huimin Wang, Junheng Liang, Xiaoying Bian, Youming Zhang
Publikováno v:
ACS Synthetic Biology. 9:2009-2022
Epothilones, as a new class of microtubule-stabilizing anticancer drugs, exhibit strong bioactivity against taxane-resistant cells and show clinical activity for the treatment of advanced breast cancer. Additionally, they also show great potential fo
Autor:
Hongkuan Wang, Longxia Xu, Kuai Li, Xiaobing Shi, Xinyu R Ma, Sukant K. Das, Hong Wen, Brianna J. Klein, Kai S Yang, Andrew Chapman, Sana Sohail, Wenshe R. Liu, Tatiana G. Kutateladze, Shiqing Xu
Publikováno v:
J Med Chem
Eleven-nineteen leukemia (ENL) protein is a histone acetylation reader essential for disease maintenance in acute leukemias, in particular, the mixed-lineage leukemia (MLL)-rearranged leukemia. In this study, we carried out high-throughput screening