Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Hongke Luo"'
Publikováno v:
International Journal of Oral Science, Vol 15, Iss 1, Pp 1-13 (2023)
Abstract Peri-implantitis is one of the most important biological complications in the field of oral implantology. Identifying the causative factors of peri-implant inflammation and osteolysis is crucial for the disease’s prevention and treatment.
Externí odkaz:
https://doaj.org/article/8731002c1dc04ba3af1cd8d899227742
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Mitophagy is an intracellular mechanism to maintain mitochondrial health by removing dysfunctional mitochondria. The E3 ligase Parkin ubiquitinates the membrane proteins on targeted mitochondria to initiate mitophagy, whereas USP30 antagonizes Parkin
Externí odkaz:
https://doaj.org/article/1dca9c2b1937460eb043572851950f61
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Mitochondrial dysfunction is a hallmark of aging and is a major contributor to neurodegenerative diseases and various cardiovascular disorders. Mitophagy, a specialized autophagic pathway to remove damaged mitochondria, provides a critical mechanism
Externí odkaz:
https://doaj.org/article/e8d4e0f213554416a89458fb00fe3b6d
Autor:
Hongke Luo1,2, Krigman, Judith1,2, Ruohan Zhang1,2,3, Mingchong Yang1,2, Nuo Sun1,2 nuo.sun@osumc.edu
Publikováno v:
Acta Physiologica. Jul2021, Vol. 232 Issue 3, p1-11. 11p.
Publikováno v:
Acta Physiol (Oxf)
Aim Mitophagy is the regulated process that targets damaged or dysfunctional mitochondria for lysosomal-mediated removal. This process is an essential element of mitochondrial quality control, and dysregulation of mitophagy may contribute to a host o
Autor:
Yuchen Guo, Yuting Liu, Yuan Wang, Weiqing Liu, Rixin Zheng, Liang Xie, Quan Yuan, Ning Kang, Hongke Luo, Yunshu Wu
Publikováno v:
Annals of the New York Academy of Sciences. 1440:54-66
Growth differentiation factor 11 (GDF11), a secreted member of the transforming growth factor-β (TGF-β) superfamily, has been reported to have the capacity to reverse age-related pathologic changes and regulate organ regeneration after injury; howe
Autor:
Yu Ban, Lin Peng, Yuchen Guo, Yuan Wang, Rixin Zheng, Yuting Liu, Hongke Luo, Quan Yuan, Weiqing Liu
Publikováno v:
Cell Proliferation
Objectives Growth differentiation factor 11 (GDF11), an emerging secreted member of the TGF‐beta superfamily, plays essential roles in development, physiology and multiple diseases; however, its role during adipogenic differentiation and the underl
Autor:
Hongke Luo, Jin Yang, Xuedong Zhou, Yujie Zhou, Hong Yang, Biao Ren, Gil Alterovitz, Lei Cheng, Fan Tang
Publikováno v:
Applied microbiology and biotechnology. 102(12)
The increase of fungal infectious diseases and lack of safe and efficacious antifungal drugs result in the urgent need of new therapeutic strategies. Here, we repurposed the lovastatin (LOV) as a synergistic antifungal potentiator to itraconazole (IT